Well said, Scott.  A very balanced viewpoint, supported by many of us.
 
Dap Louw
 
 
 
********************************************************************
Dap Louw, Ph.D.(Psych.), Ph.D. (Crim.)
Head: Centre for Psychology and the Law
Senior Professor: Department of Psychology
University of the Free State
P.O. Box 339 
Bloemfontein 
9300 South Africa 
Tel: (051) 401-2444 (work)
(051) 436-3423 (home)
Fax to pc: 088 051 436 3423 
Email: [email protected]
Cell: 083-391-8331

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>>> "Lilienfeld, Scott O" <[email protected]> 9/20/2011 1:20 PM >>>
Mike Williams wrote that "The other medications, including all the 
antidepressants, have no
treatment effect."  Mike later says, when describing the effecs of such 
medicatiions, that "there is nothing there."

    Mike, I had thought your very point was because most studies of 
antidepressants aren't conducted in a strictly double-blind fashion (because of 
medication side effects...although you didn't address active placebo studies), 
we cannot draw clear-cut conclusions from them.

    But Mike, you are now saying that we can conclude with confidence that 
antidepressants have no treatment effect.  One can't have things both ways - if 
the studies are categorically "invalid" (not merely imperfect) as you asserted 
in previous messages, then one can't draw conclusions from them one way or the 
other.  Mike, I don't follow your logic here.

      Mike, you also never responded to my points or Jim Clark's questions 
regarding your earlier claims that "all" of the dependent measures in 
antidepressant studies come from either clients or therapists themselves.  When 
I pointed out (with references to meta-analyses) that this assertion was false, 
you merely continued to reiterate your previous points without acknowledgng our 
criticisms.

    I have to confess that I'm finding this TIPS discussion regarding 
antidepressant and therapeutic efficacy increasingly troubling.  It seems to be 
more of a discussion of ideology than science.  It also seems to be marked by 
the kind of dichotomous, categorical claims (e.g., studies of therapeutic 
efficacy are "invalid", antidepressants "have no treatment effect," "there is 
nothing there," "ECT is pure behavior therapy," "ECT is a punishment 
condition," "the Beck Depression Inventory..is not a measure of mood") that we 
would rightly criticize in our students.

     Again, I am somewhat skeptical of many claims of strong antidepressant 
efficacy myself, so have no particular agenda in this debate.  But shouldn't we 
be refraining from drawing extremely strong conclusions from large, extreme 
complex bodies of literature that we all agree are challenging to interpret 
given various methodological limitations?

      I also worry that this discussion is mixing up epistemic with ontological 
assertions. It's one thing to say "I think that studies of antidepressant 
medication are inconclusive because of methodological flaws (and that many 
people have overstated the strength of evidence for their efficacy)" but 
another to say "It's clear that antidepressant medications don't work." One is 
an assertion about the evidence for claim X, the other is an assertion about 
the verimissilude of claim X.  These are two entirely different assertions, and 
Mike wants to be able to make both of them.  I don't think he can.

....Scott
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