Or sometimes more generally, 'experimentally naive' meaning not having 
previously experienced the experimental conditions, be they drugs or 
experimental manupulations.

On Jun 29, 2013, at 1:10 PM, Mike Palij wrote:

> Just to add to Miguel's points below, in drug studies and drug
> treatment/intervention studies, one is likely to come across the
> phrase "drug naive" meaning that (a) they have not experienced
> a drug, like caffeine though today it is hard to know whether
> certain drugs like caffeine have never been taken because they
> are being included in more products all the time, and (b) a
> person with a specific condition, say AIDS or depression,
> have not been treated with a particular class of drugs.  On
> the latter point, SSRIs are the first line of drugs used for
> treatment of depression (along with newer drugs like
> Norepinephrine Reuptake Inhibitors or NERI and drugs
> that have both SSRI and NERI effects) but if these drugs
> don't work, a physician might try one of the older tricyclic drugs
> like imipramine and say that they are naive to this class of
> drugs.  Though not a definitive reference, Wikipedia has an
> entry on this point; see:
> http://en.wikipedia.org/wiki/Drug-na%C3%AFve
> 
> It should be clear that, as in the case with animals that have
> previously undergone conditioning, previous experience with
> drugs even if ineffective, might influence current behavior.
> In conditioning studies, previous schedules of reinforcement
> might interaction with current schedules while with drugs expectations
> (both positive and negative) might affect how a person responds
> or interprets their experience of a drug.
> 
> -Mike Palij
> New York University
> [email protected]
> 
> 
> On Sat, 29 Jun 2013 04:20:31 -0700, Miguel Roig wrote:
>> My recollection of the use of the word 'naive' is usually in a phrase, such 
>> as
>> 'naive subjects' or perhaps 'naive rats' and was usually used in connection
>> with conditioning studies of the 1970s and earlier to describe animals that 
>> had
>> not been previously used in behavioral experiments. When used in the context 
>> of
>> human subjects research, my sense is that the term is usually used in a 
>> manner
>> consistent with Allen's post and it is typically expressed as something like
>> 'naive as to the purpose of the experiment' or 'naive as to experimental
>> hypothesis'. Actually, when reviewing certain studies with small 'n', I 
>> usually
>> look for this expression because I suspect that the expected assumption of
>> subjects' naivete as to the nature of the hypothesis/study may not be met.
> 
> ----- Original Message -----
> On  Saturday, June 29, 2013 4:33:18 AM, Allen Esterson wrote:
>> In the context of an Oxford University psychology team's research report Rick
>> Froman wondered if the term " naïve participant" was specifically British
>> usage. A Google search shows it occurs in A Dictionary of Psychology , Oxford
>> University Press, 2008 and in The SAGE Handbook of Social Psychology: Concise
>> Student Edition in line with what Rick suggested, namely, a participant who 
>> is
>> unaware of the purpose of the research or the hypothesis being tested. But it
>> also comes up in American publications, so it is not exclusively British 
>> usage:
>> http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1320&context=ijes

Paul Brandon
Emeritus Professor of Psychology
Minnesota State University, Mankato
[email protected]




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