References for Analgesia for Infants

Sucrose as a Pain Reliever for Newborn Procedures http://www.midwifeinfo.com/feature-sucrose.php

Sucrose for analgesia in newborn infants undergoing painful procedures (Cochrane Review)  http://www.cochrane.org/cochrane/revabstr/AB001069.htm

Allen, K.D., White, D.D., Walburn, J.D.: Sucrose as an analgesic agent for infants during immunization injections, Arch Pediatr Adolesc Med 150:270-274, 1996.
Barr, RG and others: "Sucrose analgesia" and diphtheria-tetanus-pertussis immunizations at 2 and 4 months, J Dev Behav Pediatr 16(4):220-225, 1995.
Blass, E.M., Hoffmeyer, L.B.: Sucrose as an analgesic for newborn infants, Pediatrics 88(3):655, 1991.
Bucher, H.U. and others: Sucrose reduces pain reaction to heel lancing in preterm infants: a placebo-controlled, randomized and masked study, Pediatr Res 38(3):332-335, 1995.
Gibbins S, Stevens B: Mechanisms of sucrose and non-nutritive sucking in procedural pain management in infants, Pain Res Manag 6(1):21-28, 2001.
Greenberg, CS: A sugar-coated pacifier reduces procedural pain in newborns, Pediatr Nurs 28(3):271-277, 2001.
Haouari, N. and others: The analgesic effect of sucrose in full term infants: a randomised controlled trial, Brit Med J 310(6993):1498-1500, 1995.
Johnston, C.C. and others: Effectiveness of oral sucrose and simulated rocking on pain response in preterm neonates, Pain 72:193-199, 1997.
Kauffman G and others: An evaluation of the effects of sucrose on neonatal pain with two commonly used circumcision methods, Am J Obstetr Gynecolo 186(3):564-568, 2002.
Miller, A., Barr, R.G., Young, S.N.: The cold pressor test in children: methodological aspects and the analgesic effect of intraoral sucrose, Pain 56(2):175-183, 1994.
Rushforth, J.A. and Levene, M.I.: The effect of sucrose on crying in response to heel stab, Arch Dis Child 69(3):388-389, 1993.
Stevens, B. and others: The efficacy of developmentally sensitive interventions and sucrose for relieving procedural pain in very low birth weight neonates, Nurs Res 48(1):35-43, 1999.
Stevens, B. and others: The efficacy of sucrose for relieving pain in neonates: a systematic review and meta-analysis, Acta Paediatr 86:837-842, 1997.
Stevens, B.J., Ohlsson A: Sucrose for analgesia in newborn infants undergoing painful procedures, Cochrane Database of Systematic Reviews 4:CD001069, 2001.
NOTES:

To make an approximate 24% sucrose solution, add 1 teaspoon of table sugar to 4 teaspoons of sterile water. Use this solution to coat the pacifier or administer 2 ml to the tongue 2 minutes before the procedure.

Sarah Kuykendall wrote:

Last night I started a 6-week-old in ER.  They'd given her sucrosewhich they claim calms babies (children?) and reduces pain.  She was calm,but also sick so we weren't sure which was the reason.  The MD claimedthis is a fairly common thing now. Any of you using this?  Thanks! Sarah Kuykendall
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