According to an analysis of the COOL clinical trial data, there was a 91% success rate when Cathflo was instilled in catheters with thrombotic occlusions < 24 hours old. For clots formed within 24 hours up to 2 weeks, the rate of success was still good but a bit lower at 87% (I think that is the right %). It drops a bit more after 2 weeks.

The take-home message is to still always try Cathflo no matter how old the occlusion, but that the sooner it is used the greater the chance of success.

Nadine Nakazawa



From: "Fritz, Donna" <[EMAIL PROTECTED]>
To: [EMAIL PROTECTED]
Subject: Tpa and old clots
Date: Mon, 9 Oct 2006 16:59:39 -0600

How long after clot formation can tpa be used with reasonable success?
I had a case today where 2 lumens of a triple arrow had been clotted for
about 5 days.




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