To re-order your scaffolds based on synteny, try running ABACAS which is
available from:

 http://www.sanger.ac.uk/resources/software/pagit/

-Matt Berriman


On 05/01/2012 11:01 am, "Tim Carver" <[email protected]> wrote:

> Hi Astrid
> 
> When you do the blast between the assembled sequence and reference sequence
> both sequences need to be in single fasta format (i.e. not multiple fasta).
> The assembled sequence is likely to be in a multiple fasta format, so you
> will need to load that into Artemis first and save it out as a single fasta
> (from the menu: File->Write->All Bases->FASTA format). Then repeat the blast
> comparison using this and the coordinates for the blast hits will appear
> correctly in ACT along all scaffolds.
> 
> I am not sure why your scaffolds are ordered by size and how likely that is
> for your assembled sequence.
> 
> Regards
> Tim
> 
> On 1/5/12 9:36 AM, "Astrid von Mentzer" <[email protected]> wrote:
> 
>> Hi, 
>> 
>> I have an assembled sequence (Velvet) which I have compared to a reference
>> sequence in ACT. I have run a blastall between the sequences. When I view the
>> comparison in ACT, the scaffolds are ordered in size with the biggest first
>> and only the biggest scaffold is compared to the reference sequence.
>> 
>> What I wonder first is: Why are the scaffolds ordered according to size? How
>> do I make a comparison between all scaffolds (the whole sequence) to the
>> reference strain and not just one scaffold?
>> 
>> I am new to this so please describe in detail so I understand.
>> 
>> Cheers, 
>> Astrid
>> 
>> 
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> 
> 
> 
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