Hi Astrid

You can load in the sequences from the command line:

act   refH10407.fasta   6732_2#8_refH10407.crunch   6732_2#8_refH10407.fasta

i.e. act subject_sequence comparison_file query_sequence
 
Then (as per the documentation
http://abacas.sourceforge.net/documentation.html) load in the tab file from
the File menu.

To compare another sequence against your reference you would need to use
formatdb with the reference sequence, e.g.

formatdb -p F -i refH10407.fasta

Then using blastall:

blastall  -p blastn  -m 8  -d  refH10407.fasta  -i   other_sequence.fa  -o
comparison.blast

Where Œother_sequence.fa¹ is the FASTA sequence of the other geneome. Œ-m 8¹
generates the correct output format for ACT.
Alternatively have a look at WebACT or Double ACT to generate the comparison
for you:

http://www.webact.org/WebACT/home
http://www.hpa-bioinfotools.org.uk/pise/double_act.html

Regards
Tim


On 2/23/12 9:06 AM, "Astrid von Mentzer" <[email protected]> wrote:

> I have run ABACAS on my sequences and the following output files was the
> result:
> 
> 6732_2#8_refH10407.bin
> 6732_2#8_refH10407.crunch
> 6732_2#8_refH10407.fasta
> 6732_2#8_refH10407.gaps
> 6732_2#8_refH10407.gaps.stats
> 6732_2#8_refH10407.gaps.tab
> 6732_2#8_refH10407.tab
> 
> I want to compare the sequence to my reference.
> 
> In what place would I put which files? See below:
> 
> ACT:
> 
> Sequence 1:
> Comparison file:
> Sequence 2:
> 
> I also want to view my sequence against another gene sequence. Correct me if I
> am wrong, I would need to run a blast and then use the output comparison file
> in ACT? Which blast script would one prefer? I have hear of blastall, blast by
> MLST but I don't know why to choose either of them.
> 
> Thanks in advance!
> 
> Regards, 
> Astrid
> ---
> Astrid von Mentzer, PhD-student
> University of Gothenburg
> Institute of Biomedicine
> Department of Microbiology and Immunology
> Box 435
> 405 30 Göteborg
> Sweden
> 
> Phone: +46 31 786 62 21
> Fax: +46 31 786 62 05
> 
> 
> 
> 
> 
> 
> 
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