Nicklas Nordborg writes:
 > Bob MacCallum wrote:
 > > For two colour designs, we usually only inherit from the "experimental"
 > > biosource. (Explanation: an experimental samples might be annotated as
 > > "Infected with E. coli", "Infected with S. aureus" and so on, and the 
 > > control
 > > samples would be annotated as "Mock infected with PBS".)
 > > 
 > > It looks like the automatic inheritance will also inherit from the the
 > > "control" biosource.
 > 
 > Yes, it will inherit all annotations that it can find, because it can't 
 > tell which ones are "important" and which ones are not.
 > 
 > But... would it help to be able to mark some items (eg. the control sample)
 > as "Not suitable for inheriting annotations"? It could be a boolean flag
 > that causes the automatic function to ignore annotations on it. Comments?

Yes, that would be a nice simple solution, especially if this flag can be set
by the bulk item importers.

 > 
 > > We have to inherit from just one of the two biosources because BASE
 > > doesn't know which is experimental (ch1) and which is control (ch2).
 > > BASE will later choose one arbitrarily (in Experiment Explorer for
 > > example).
 > 
 > No, this was a bug that was fixed in BASE 2.5. Since then, all inherited 
 > annotations are displayed and can be used in the analysis.

Oops, sorry for spreading misinformation.  We've only inherited from one
biosource for a long time now, so never experienced that fix.  We'll continue
to inherit from just the experimental biosource because we use that
inheritance to flag the ch1 sample (detected by our code which we run on top
of BASE).

cheers,
Bob.

-- 
Bob MacCallum | VectorBase Developer | Kafatos/Christophides Groups |
Division of Cell and Molecular Biology | Imperial College London |
Phone +442075941945 | Email [EMAIL PROTECTED]

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