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Hi,

I'm trying to get a crystal for one protein and so far i can only get
some small ones.However the crystals were grown from the
perticipate.After I set up the trays, the first several days i only
saw perticipitate, and then after 10 days, lots of tiny crystals show
up.I tried to use the additive screen, but still didn't change much.In
order to get a bigger crystal, what can I do the next step?

I was thinking about seeding, is there any protocol for doing this?I'm
a little confused about one thing is that after I crushed the
crystals, I need to add to the pre-equilibrium solution, does this
mean, in my case, I should put the tiny crystals into the trays that I
already set up for 10 days?I'm using haning drop right now.Is it
easier to use sitting drop instead to do seeding?Any suggestions would
be appreciated.

Thanks.

Jenny

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