I would like to compare several very similar structures (more than 10) to get 
the rms deviation over all. Is this possible with any program?
Thanks
Katie Carr
University of Nottingham

-----Original Message-----
From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of Eleanor 
Dodson
Sent: 14 April 2011 11:51
To: [email protected]
Subject: Re: [ccp4bb] Comparing two proteins

On 04/13/2011 09:18 PM, REX PALMER wrote:
> Dear All
> What is the best program to use for comparing two protein structures which 
> are very similar both structurally and wrt aa sequence? ie to get the rms 
> deviations both generally and in selected regions.
>
> Rex Palmer
> Birkbeck College


Using CCP4 go to the coordinate utility

Superpose molecules

You can either compare things using secondary structure or by specifying 
residue spans

Underlying programs are PISA (also available at the BI msd server) and 
LSQKAB

Eleanor
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