I'm going with Jurgen on this one. 

http://img27.imageshack.us/img27/3232/pastedgraphic1.png


Sad was the day when I mounted this puppy and it shot to 8-10A. Room 
temperature. And messing around with cryos didn't help either. 


Can't remember the size, but I think I had scooped it with a 0.8 mm loop.  

I should've mounted it on a ring and given it to my wife. And that's not 
chromatic artifact, the ligand was red. 

On a side note, I had a very small crystal embedded in a chunk of ice at the 
end of a 0.025 mm loop.  Couldn't even see it on the very nice on-axis cameras 
at the ALS. I shot blindly into the ice.. .it diffracted to about 1.8A (and the 
ice wasn't bad at all)


F


On Feb 7, 2012, at 9:52 AM, Bosch, Juergen wrote:

> Hi Enrico,
> 
> I was just looking at non-optimal cryo-conditions and the original posters 
> starting point.
> Of course if you have a good cryo bigger is better for the reasons you write 
> but if you have no clue how your crystals will perform then I'd rather go for 
> small to be cautious and also have those around and not only the big ones 
> which everybody mounts because they looks so nice. To be disappointed by big 
> crystals is often not a surprise to me and if you have not tried small 
> crystals from the same batch well then you missed 50% of your chances to 
> solve s structure with the first light the crystals saw.
> 
> Jürgen
> 
> 

---------------------------------------------
Francis E. Reyes M.Sc.
215 UCB
University of Colorado at Boulder

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