Hi Rajnandani,

 

The cheaper DIY protocol that Herman referred to, is actually still in use by 
us. Use a siliconizing solution (e.g. Serva 35130.02 silicone solution in 
isopropanol). Put about 20-30 microliters on the coverslips, preferrably with a 
repeating pipette and in a fumehood. Then put the coverslips in an oven at 
110*C for about 75 minutes.

 

Best,

Tjaard

 

Dr. Ing. Tjaard Pijning

 

Structural Biology Group

Faculty of Science and Engineering, University of Groningen

9747 AG Groningen, The Netherlands

+31(0)50 363 4385  |  [email protected]

 

From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of 
[email protected]
Sent: 31 januari 2019 10:17
To: [email protected]
Subject: [ccp4bb] AW: [EXTERNAL] [ccp4bb] Is there any alternative to 
siliconized glass coverslips for crystallization?

 

A long time ago, before siliconized coverslips became commercially available, 
we used to siliconize coverslips ourselves. It is not really that much work and 
unsiliconized cover slips should be very cheap. If you wish, I could try to 
find back the protocol.

Best,

Herman

 

Von: CCP4 bulletin board [mailto:[email protected]] Im Auftrag von 
Rajnandani Kashyap
Gesendet: Donnerstag, 31. Januar 2019 09:17
An: [email protected]
Betreff: [EXTERNAL] [ccp4bb] Is there any alternative to siliconized glass 
coverslips for crystallization?

 

Dear All

I am a PhD student who requires lots of coverslips (!!) for setting up hanging 
drop crystallization. The company sells it for a huge amount. Also there is a 
wide monetary difference between a normal siliconized coverslip and a 22mm 
siliconized circle coverslips. We tried to search for an alternative companies 
but couldn't get any one who sells coverslips with the same dimensions 
(0.19-0.22mm glass thickness and 22 mm glass diameter). Is there any 
alternative company (distribution in India) from where we can buy them for a 
reasonable price?

Thanks in advance for sparing your valuable time and efforts.

 

Regards

Rajnandani Kashyap

India

 

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