Dear Colleagues,
Scaleit is a terrific program. 
Amongst its strengths already listed I would also mention its breakdown table 
with F so that in the strongest F reflections bin any systematic errors between 
the two data sets can show up if the Rfactor is greater than about 1%. 
Greetings,
John 
Emeritus Professor John R Helliwell DSc




> On 26 Jul 2022, at 11:40, Eleanor Dodson 
> <[email protected]> wrote:
> 
> 
> Not only does SCALEIT do the job - it presented useful plots and an 
> informative log file..
> Eleanor
> (You need to run CAD hklin1 Xtal1.mtz hklin2 Xtal2.mtz ...and obviously the 
> columns from each Xtal will need different labels..)
> 
>> On Tue, 26 Jul 2022 at 09:45, Phil Evans <[email protected]> wrote:
>> If you give Pointless Fs, it squares them to Is (not correct if the Fs have 
>> been derived from the truncate procedure, but not too bad). It will then 
>> give you a comparison. If you give the two datasets to Pointless, labelling 
>> them as different datasets, you can use Aimless to compare them
>> 
>> But as Andrew said, the appropriate CCP4 program is Scaleit: it’s old but 
>> still works and gives lots of statistics 
>> 
>> Phil
>> 
>> Sent from my iPhone
>> 
>>>> On 26 Jul 2022, at 09:37, Andrew Leslie - MRC LMB 
>>>> <[email protected]> wrote:
>>>> 
>>> I think that POINTLESS works with intensities rather than structure 
>>> factors (I’m not sure if this can be changed). Also, SCALEIT gives a much 
>>> more detailed breakdown (R factors as a function of resolution and 
>>> differences in terms of sigmas etc) than POINTLESS WILL.
>>> 
>>> Cheers,
>>> 
>>> Andrew
>>> 
>>>> On 26 Jul 2022, at 09:24, LEGRAND Pierre 
>>>> <[email protected]> wrote:
>>>> 
>>>> Hello Mirek,
>>>> 
>>>> A very quick approach for that is offered by pointless:
>>>> 
>>>> pointless HKLREF 1_1_aimless.mtz  HKLIN 2_1_aimless.mtz
>>>> or
>>>> pointless HKLREF 1_1_aimless.mtz  XDSIN XDS_ASCII.HK
>>>> 
>>>> You will obtain a table looking like that, taking into account to possible 
>>>> reindexing:
>>>> 
>>>> Alternative indexing scores relative to reference
>>>>        Alternative reindexing        Lklhd      CC     R(E^2)    Number 
>>>> Cell_deviation
>>>>  1              [h,k,l]              0.993    0.962    0.118     19150     
>>>>  0.08
>>>>  2              [-k,h,l]             0.007    0.078    0.512     19150     
>>>>  0.87
>>>> 
>>>> 
>>>> Best wishes,
>>>> 
>>>> Pierre Legrand
>>>> PROXIMA-1 Beamline
>>>> Synchrotron SOLEIL
>>>> 
>>>> De: "Nicolas Foos" <[email protected]>
>>>> À: [email protected]
>>>> Envoyé: Mardi 26 Juillet 2022 08:36:35
>>>> Objet: Re: [ccp4bb] Comparing two datasets
>>>> 
>>>> Hi Mirek, 
>>>> 
>>>> I am pretty sure XSCALE will do that for you : 
>>>> https://xds.mr.mpg.de/html_doc/xscale_program.html
>>>> 
>>>> If not, maybe have a look on SHELXC in SIR mode. 
>>>> 
>>>> Hope this help. 
>>>> 
>>>> Nicolas
>>>> 
>>>> On 25/07/2022 21:52, Cygler, Miroslaw wrote:
>>>> Hi,
>>>> I would like to calculate the R-merge for Fs from two datasets processed 
>>>> from two different crystals. Tried to use Blend but got the message that 
>>>> Blend requires R. Downloaded R but do not know how to tell CCP4 where it 
>>>> is located on my Mac. Is there another program that would take two mtg 
>>>> files and merge the Fs?
>>>> Any help would be greatly appreciated. 
>>>> 
>>>> 
>>>> Mirek
>>>> 
>>>> 
>>>> 
>>>> 
>>>> 
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>>>> -- 
>>>> Nicolas Foos PhD - ARISE fellow
>>>> https://orcid.org/0000-0003-2331-8399
>>>>    
>>>> EMBL Grenoble, McCarthy Team
>>>> 71 av. des Martyrs, 
>>>> 38000 Grenoble FRANCE
>>>>    
>>>> +33 4 57 42 84 67
>>>> 
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