Yes ther eis no titration of dose. Therefore if there is an effect that is irrespective of the magnitude of the dosage, I start suspecting a placebo or Hawthorne effect. A plain google search turns up far too much uncontrolled garbage.
On 12/4/05, Dana <[EMAIL PROTECTED]> wrote: > ok I went and looked anyway. It does say that there is a benefit if the > doses are pooled. Not quite sure what that means, but it does tend to > indicate that the issue is a little more complex than you portray it to be. > Again. > > Dana > > > On 12/4/05, Dana <[EMAIL PROTECTED]> wrote: > > > > tsk as usually you are poo pooing without reading. You'd be funny if you > > weren't so condescending. The attitude of real science indeed. > > > > Hello, I am talking about anticoagulation, as Sam has already realized. > > Remember that the next time you call him a Neanderthal. > > > > As for your study, don't have time. It may say this but given your track > > record I am willing to bet it says more than that too. In any event there > > are other studies, peer-reviewed, my friend. See the archives; posted them > > this summer. Ther aren't a lot -- there are problems with establishing a > > standard does as I have already mentioned. > > > > Dana > > > > > > > > On 12/4/05, Larry C. Lyons <[EMAIL PROTECTED]> wrote: > > > > > > I think that this Cocheran based meta analysis summarizes the attitude > > > of real science, there is no real effect for ginko beyond a placebo. > > > > > > http://www.antiwrap.com/?789 > > > > > > Ginkgo biloba Compared with Cholinesterase Inhibitors in the Treatment > > > of Dementia: A Review Based on Meta-Analyses by the Cochrane > > > Collaboration > > > A. Kurza, B. Van Baelenb > > > > > > aDepartment of Psychiatry and Psychotherapy, Technical University > > > Munich, Munich, Germany; > > > bMedisearch International, Mechelen, Belgium > > > > > > Dementia and Geriatric Cognitive Disorders 2004;18:217-226 (DOI: > > > 10.1159/000079388) > > > > > > Abstract > > > > > > Data were derived from the Cochrane Collaboration meta-analyses of the > > > efficacies of ginkgo, donepezil, rivastigmine and galantamine on > > > changes in cognitive function in patients with dementia and, where > > > necessary, were transformed to standardized mean differences. The > > > proportion of patients discontinuing trials was used as a proxy > > > measure of tolerability. Outcomes were assessed after 6 months of > > > treatment. Trial data for cholinesterase inhibitors were more > > > consistent than those for ginkgo, particularly regarding patient > > > populations and outcome measures. Significant benefits on cognition > > > vs. placebo were seen with donepezil, 5 and 10 mg, rivastigmine, 6-12 > > > mg, and galantamine, 16 and 24 mg. Significant benefit vs. placebo > > > with ginkgo was seen only when all doses were pooled. Similar > > > proportions of patients discontinued treatment with ginkgo and > > > placebo. Cholinesterase inhibitors were also well tolerated, although > > > a significantly greater proportion of patients receiving active > > > treatment discontinued vs. placebo with some doses. An evidence-based > > > medicine approach, taking into account the quality of clinical trials, > > > is essential when assessing the safety and efficacy of medications. > > > -- > > > > > > > > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~| Discover CFTicket - The leading ColdFusion Help Desk and Trouble Ticket application http://www.houseoffusion.com/banners/view.cfm?bannerid=48 Message: http://www.houseoffusion.com/lists.cfm/link=i:5:185707 Archives: http://www.houseoffusion.com/cf_lists/threads.cfm/5 Subscription: http://www.houseoffusion.com/lists.cfm/link=s:5 Unsubscribe: http://www.houseoffusion.com/cf_lists/unsubscribe.cfm?user=11502.10531.5 Donations & Support: http://www.houseoffusion.com/tiny.cfm/54
