--- In [email protected], "hey00nanc" <[EMAIL PROTECTED]> wrote: > > --- In [email protected], "sshine2412" <[EMAIL PROTECTED]> wrote: > > > > Does anybody know how long Gleevec lasts? It looks like most people > > are still in remission 4 or 5 years after taking this medicine, but > > I'm wondering if anyone knows about long term benefits (5-10+ > > years). > > _______________ > > Hi sshine, > > Gleevec has only been taken now for about 6 years by those in the > earliest trials....I have been on Gleevec for 5 years (and still > kicking!) > > Part of the answer depends on the level of response that you get from > Gleevec....ie, whether you have a cytogenetic response, get to CCR or > PCRU. There are different relapse rate %s depending on your response > to the drug. At CCR, the relaspse rate is 2% a year. > > Recently, Dr. Druker told me that he can now confidently tell a newly > diagnosed patient that their CML will be a chronic disease, managed by > drugs. If someone goes on Gleevec now and eventually relapses, there > will be the other 2nd generation drugs available (probably BMS and > AMN, now in trials). So, no long history with Gleevec but a good > outlook. > > Nancy C.
Nancy,and friends who have been following our stories..... I just got the word from Dr. Talpaz and I must admit that I'm a bit disappointed. After visiting him, I felt so good. Now, I feel like a just got a kick in the butt! Only 5 of the 20 cells analyzed were negative which means resistance to Gleevec is definately a possibility. My molecular studies show a high level of disease, also. He has suggested trying to take 800 mg. to see if it's a real issue of resistance. I will return in July. I guess I must seriously start considering other options - BMS being 1st on my list. I would love to hear from others who have been down this road. I'm a bit shaken. Dianne ------------------------ Yahoo! Groups Sponsor --------------------~--> Help save the life of a child. Support St. Jude Children's Research Hospital's 'Thanks & Giving.' http://us.click.yahoo.com/0iazvD/5WnJAA/xGEGAA/8zSolB/TM --------------------------------------------------------------------~-> New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/CML/ <*> To unsubscribe from this group, send an email to: [EMAIL PROTECTED] <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
