Jeanie,
Increasing the dosage of Gleevec will often suppress the counts of the
granulocyte cell lines (neutrophils, eosinophils, basophils), but will
not normally affect the lymphocyte cells (T-cells, B-cells, etc) by
creating either smudge cells (fragile lymphocyte cells that break open
easily) or atypical lymphocyte cells (odd sizes, shapes, or nucleus),
neither of which are normally associated with CML.  I would ask the
doc about the smudge cells and atypical lymphocytes.
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[CMLHope]
A support group of http://cmlhope.com
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