Hi Daniel: I am on Gleevec since diagnosis in March '09 and hit a MHR and CCR early but I still have a trace in molecular testing. I also have lots of fatigue with Gleevec and I need Aranesp to stimulate red cell growth every other month or so. Hopefully the fluctuation you are experiencing is temporary but please keep the group updated. It is very helpful for the rest of us, especially those of us who are newer to this illness, to know what is going on with our CML friends. Best wishes to you for a great year.
Marcie Baltimore -----Original Message----- From: daniel <[email protected]> To: CMLHope <[email protected]> Sent: Thu, Feb 10, 2011 8:19 pm Subject: [CMLHope] Re: pcr count increased last visit btw, i am different daniel from the one making political comments and agree it is best to keep such thing to oneself in this forum. On Feb 10, 8:18 pm, daniel <[email protected]> wrote: hi all, i have had cml for about 3.5 years, and was originally on gleevec, but transferred to tasigna about a year ago due to fatigue issues with gleevec. i obtained ccr in the first year and since then my pcr has been stable, between a 2 and 3 log reduction. in the my previous quarterly visit my pcr had dropped to 3 log reduction for the first time (good news). but at my most recent visit it is back up to around the level it has been around for the past 2 years (bad news). my dr and i are concerned to see such an increase and i have a follow-up pcr in 5 weeks to see if it is still rising. my question is have other experienced similar increases? is it common to experience temporary fluctuation or does such a change usually indicate loss of response? obviously, i am very concerned and going to follow up regardless, but would be good to get a sense of others' experiences. thanks, daniel -- CMLHope] support group of http://cmlhope.com ------------------------------------------------ You received this message because you are subscribed to the Google Groups CMLHope" group. o post to this group, send email to [email protected] o unsubscribe from this group, send email to [email protected] or more options, visit this group at http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope
