First Y A H O O O !!! Y II P P E E !!!
Number 1378 in the Zero Club Zavie I assign a Zero Club number once you reach CCR. I don't recall assigning you one in the past, so enjoy it. PCR values tend to fluctuate. It takes 3 consecutive results to establish a trend. I would only worry if there as a 1 log or greater change and then ask to be retested. It looks like your doctor is right on top of it. I can say don't worry, but if I had a 1 log increase I would ask to be retested. Zavie Zavie Miller (age 72) Ottawa, Canada, K2G 3X3 dxd AUG/99 INF OCT/99 to FEB/00, CHF No meds FEB/00 to JAN/01 Gleevec since MAR/27/01 (400 mg) CCR SEP/01. #102 in Zero Club 2.8 log reduction Sep/05 3.0 log reduction Jan/06 2.9 log reduction Feb/07 3.6 log reduction Apr/08 3.6 log reduction Sep/08 3.7 log reduction Jan/09 3.8 log reduction May/09 3.8 log reduction Aug/09 4.0 log reduction Dec/09 4.4 log reduction e-mail: [email protected] On Thu, Feb 10, 2011 at 8:18 PM, daniel <[email protected]> wrote: > hi all, > i have had cml for about 3.5 years, and was originally on gleevec, but > transferred to tasigna about a year ago due to fatigue issues with > gleevec. i obtained ccr in the first year and since then my pcr has > been stable, between a 2 and 3 log reduction. in the my previous > quarterly visit my pcr had dropped to 3 log reduction for the first > time (good news). but at my most recent visit it is back up to around > the level it has been around for the past 2 years (bad news). my dr > and i are concerned to see such an increase and i have a follow-up pcr > in 5 weeks to see if it is still rising. > > my question is have other experienced similar increases? is it common > to experience temporary fluctuation or does such a change usually > indicate loss of response? obviously, i am very concerned and going to > follow up regardless, but would be good to get a sense of others' > experiences. > > thanks, > daniel > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at > http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope

