Hi all >From my experience gleevec quit working for me after 5 years--it probably was >a mutation but was never told. I started on full dose tasigna but it quit >working after only a few months. I then was placed on 150 Mgs sprycel. It worked great with no PE. However some people do get PE from sprycel. I am now on 100 Mgs daily sprycel. Work with the doctor and keep good checks on the blood. Blessings Jeanie🐟
Sent from my iPhone > On Jan 2, 2015, at 6:39 AM, Choi <[email protected]> wrote: > > Dear group, > > Hi, This is Choi from South Korea. I just wonder if anyone here has E355G > mutation? > One of my friends diagnosed with CML Chronic phase in 2012, started Gleevec > for about 16 months. > He developed mutation; E355G, so switched to Sprycel. After 1 years on > Sprycel, E355G mutation disappered but He is suffering from severe pulmonary > hypertension. > PCR level is hovering 0.37 ~ 0.45 for 1 year. It doesn't drop under 0.1 > > He wants to escape from pulmonary hypertension and also hopes to drop PCR > level under 0.1. > To drop PCR level is increasing Sprycel but it will accelerate side effects. > to decreas side effects will be stoping Sprycel but worry about E355G > mutation recurring. > He is just wondering if he could switch to Tasigna safely without E355G > recurring. > > Can anyone advise? > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
