Hi all I really enjoyed this article as it has a lot if info on cml and tkis even if it is out if date still good info. Blessings Jeanue🐟
Sent from my iPhone > On Jan 4, 2015, at 7:26 AM, Giora <[email protected]> wrote: > > Hi > This good article is 3 years old from ASH 2011. The new data about stopping > treatment presented last month at ASH 2014, is not included there and some of > the data in the article is outdates. (for example there is already trials on > stopping after 2 ed generation TKIs. > If you want to read summaries of the latest data from ASH 2014, including > stopping treatment, data on Ponatinib and more, you can go to our website and > read our summaries from ASH. > www.cmladvocates.net > there are already 3 reports published and the last one on CML in children > will be published soon. > Happy new year to all > Giora > > From: [email protected] [mailto:[email protected]] > Sent: Sunday, January 04, 2015 1:59 PM > To: [email protected] > Subject: [CMLHope] Good article on stopping tki > > http://asheducationbook.hematologylibrary.org/content/2011/1/136.full > > Sent from my iPhone > > On Jan 3, 2015, at 11:28 AM, "'Icandoallttc' via CMLHope" > <[email protected]> wrote: > > Hi all > > From my experience gleevec quit working for me after 5 years--it probably was > a mutation but was never told. I started on full dose tasigna but it quit > working after only a few months. > I then was placed on 150 Mgs sprycel. It worked great with no PE. However > some people do get PE from sprycel. > I am now on 100 Mgs daily sprycel. > Work with the doctor and keep good checks on the blood. > Blessings > Jeanie🐟 > > > > Sent from my iPhone > > On Jan 2, 2015, at 6:39 AM, Choi <[email protected]> wrote: > > Dear group, > > Hi, This is Choi from South Korea. I just wonder if anyone here has E355G > mutation? > One of my friends diagnosed with CML Chronic phase in 2012, started Gleevec > for about 16 months. > He developed mutation; E355G, so switched to Sprycel. After 1 years on > Sprycel, E355G mutation disappered but He is suffering from severe pulmonary > hypertension. > PCR level is hovering 0.37 ~ 0.45 for 1 year. It doesn't drop under 0.1 > > He wants to escape from pulmonary hypertension and also hopes to drop PCR > level under 0.1. > To drop PCR level is increasing Sprycel but it will accelerate side effects. > to decreas side effects will be stoping Sprycel but worry about E355G > mutation recurring. > He is just wondering if he could switch to Tasigna safely without E355G > recurring. > > Can anyone advise? > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
