It makes sense. The phosphorylation of a protein changes its shape. We can 
think of these different conformal shapes as different logical conditions 
or states.

LC

On Sunday, October 4, 2020 at 7:07:49 AM UTC-5 [email protected] wrote:

> In the September 25 2020 issue of the journal Science researchers report 
> on the invention of a sequence of switches made entirely of protein that 
> can perform AND OR and NOT Boolean logical operations, and thus is Turing 
> Complete, they call it Co-LOCKR.  And they were able to put this simple 
> computer into a T-Cell antibody, and so they could activate the T-Cell 
> only when specific conditions are met.  
>
> Designed protein logic to target cells with precise combinations of 
> surface antigens <https://science.sciencemag.org/content/369/6511/1637>
>
> By examining the antigens on the surface of a specific type of cancer 
> cell you can distinguish cancer cells from healthy normal cells, but it's 
> more complex than just looking for one specific antigen. However with 
> Co-LOCKR a T-Cell could be programmed for example, to only attack cells 
> that have antigens W OR X  AND NOT both on their surface, AND antigen Y, 
> AND NOT antigen Z. That way the T cell would attack cancerous cells but 
> leave normal healthy cells alone. This is almost starting to sound a little 
> like a simplified version of one of Drexler's Nanomachines. 
>
>  John K Clark
>

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