There is NO way that his weakness is the direct result of his leukemia virus, because all the leukemia virus does is weaken the immune system to other diseases.  So if it is the result of a disease, it is some other disease-- which he may have gotten due to having a compromised immune system from the FeLV.  Or an injury. There are long-term effects of depo, including muscle wasting. When did the depo end? If it is from the depo I would have expected it to start while he was still on the depo, as that is when his muscles would have been wasting. Our dog who was on steroids long-term developed weakness in her hind end also, but she developed it while on the steroids.
Michelle

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