Thanks for your reply but in my case it did not solve the problem...
has anyone else good ideas to speed up galaxy?

Cheers Jochen

On 09.12.2016 17:07, Hendrickson, Curtis (Campus) wrote:
> Jochen
> We once had a similar, sudden performance problem, and found that the setting
>       Galaxy.ini: debug = False
> Had accidentally been re-set to "True". Having "debug" turned on really, 
> really slows down the galaxy app process....
> So, check that debug = False. 
> Regards
> Curtis
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