From the Wikipedia article on Delrin:

Delrin has also recently found use in the manufacturing of Irish  
flutes (traditionally made of wood), tin whistles (traditionally made  
of metal), and bagpipes (traditionally made of wood). Delrin flutes  
sound similar or identical to wooden flutes, but have none of the  
shrinkage or cracking issues usually associated with wooden  
instruments in hot, cold, or dry environments. Builders such as Des  
Seery, Michael Cronnolly of M&E Flutes, Tony Dixon, and Rob Forbes all  
build Delrin flutes.
Delrin has become an increasingly popular material in the fabrication  
of guitar picks. It has excellent durability; it is much more  
resistant to wear than nylon at the point of string contact,  
especially on round-wound strings. Delrin does not crack or break like  
celluloid or polyvinyl chloride (PVC), provides a solid, slip-free  
grip, and develops a "memory" over time; that is, it gradually  
develops a slight curvature that conforms to the user's grip.
Delrin is also much treasured by many makers and players of  
harpsichords, being used for the plectra, which pluck the strings when  
a key is pressed. Delrin has been found to provide a tonal quality  
very similar to that of the bird-quill used in the heyday of the  
instrument, while being far more durable and consistent.


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