I would like to make pairwise comparisons of topological similarity between
all possible combinations of 518 gene trees.

The expected output would be a matrix of topological distances for each
gene tree to each other tree.

Any suggestions?

Also as an aside, is there a way to mechanize the estimation of 100s of
gene trees from alignments, such that the best model models of nucleotide
substitution is chosen objectively and then a tree is generated using
likelihood or Bayesian methods. Ideally I give the program the folder of
100s of alignments and tell it to go and wait for the gene trees.

Best
Chris Buddenhagen
Florida State University
[email protected]

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