[ccp4bb] Vacancy for a Scientific Programmer at EMDB (EMBL-EBI, Cambridge, UK)

2022-09-14 Thread Gerard Kleywegt

Dear colleagues,

EMBL-EBI is looking to recruit a Scientific Programmer to work on the Electron
Microscopy Data Bank (EMDB; emdb-empiar.org), one of the three core archives of
the Worldwide Protein Data Bank organisation (wwPDB; wwpdb.org).

The Scientific Programmer will work in a small but tight international team
focusing on managing the flow of data into the archive (data-in; deposition,
validation and curation) and the public release of the data (production). In the
past two years, EMDB has doubled in size to over 20,000 entries and the archive
is set to continue to grow very rapidly in the years to come, so this is a very
exciting time to join the effort.

More information can be found in the vacancy notice at
https://www.embl.org/jobs/position/EBI02066

A detailed description of the role and its requirements is available from
https://oc.ebi.ac.uk/s/j1g7grHEJoeO9BJ

The application period for this post will close on 23 October 2022 and (virtual)
interviews will take place on 17 or 18 November.

Please feel free to bring this position to the attention of anyone with the
right skillset who might be interested.

Best wishes,

Gerard Kleywegt

---
Gerard J. Kleywegt, EMBL-EBI, Hinxton, UK
Head of Molecular and  Cellular Structure
ger...@ebi.ac.uk pdbe.org emdb-empiar.org
PA: Roisin Dunloppdbe_ad...@ebi.ac.uk



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[ccp4bb] Vacancy for EMDB Team Leader (EMBL Faculty position)

2022-07-18 Thread Gerard Kleywegt

Dear colleagues,

EMBL-EBI is looking to recruit a new Team Leader (EMBL Faculty position) to 
take charge of the Electron Microscopy Data Bank (EMDB; emdb-empiar.org), one 
of the three core archives of the Worldwide Protein Data Bank organisation 
(wwPDB; wwpdb.org).


In the past two years, EMDB has doubled in size to over 20,000 entries and the 
archive is set to continue to grow very rapidly in the years to come. We are 
therefore looking for an ambitious, mid-career scientist who has the skills, 
drive and vision to manage this expansion, with the help of the extant EMDB 
team (7 staff members at present), in collaboration with our wwPDB colleagues, 
and in consultation with the cryo-EM community.


The activities of the EMDB team include archival, curation, integration, 
visualisation, validation and dissemination of cryo-EM data, weekly production 
processes, planning, coordinating and working with our wwPDB partners, and 
outreach, training and public engagement. We expect the successful candidate to 
have ample experience with, and a good practical and theoretical understanding 
of cryo-EM/ET; to have experience carrying out scientific software development; 
as well as an ability to write successful grants, to manage projects, and to 
lead a team of scientists and software developers.


More details can be found in the vacancy notice at 
https://www.embl.org/jobs/position/EBI02047


The vacancy will close on 18 September 2022 and (virtual) interviews will take 
place on Thursday 20 October.


Please feel free to bring this position to the attention of anyone with the 
right skillset who might be interested.


Best wishes,

Gerard Kleywegt

---
Gerard J. Kleywegt, EMBL-EBI, Hinxton, UK
Head of Molecular and  Cellular Structure
ger...@ebi.ac.uk pdbe.org emdb-empiar.org
PA: Roisin Dunloppdbe_ad...@ebi.ac.uk



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[ccp4bb] Vacancy: Beamline Scientist at Diamond Light Source UK

2022-06-28 Thread Harkiolaki, Maria (DLSLtd,RAL,LSCI)
Dear all,

We are looking for a beamline scientist to join our team at beamline B24 at the 
UK synchrotron, Diamond Light Source.

This is a 3-year fixed post that will provide the successful candidate with 
ample opportunity to contribute to developments in the field of correlative 
cryo-imaging and develop skills on both synchrotron and microscopy/tomography 
instrumentation and design.

You can find out more about the beamline at:
https://www.diamond.ac.uk/Instruments/Biological-Cryo-Imaging/B24.html

The vacancy can be found at:
https://vacancies.diamond.ac.uk/vacancy/beamline-scientist-490383.html

If you have any questions regarding this post, feel free to get in touch and 
please note that the deadline for applications is this Sunday (!)…

All the best,

Maria




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[ccp4bb] Vacancy: Group Leader role in Science IT

2021-09-17 Thread Ashton Alun (PSI)

We have a new opportunity for someone to join the Science IT Infrastructure and 
Services department to contribute and lead a group tasked with the software 
environment for the operations and rapidly evolving developments needed for 
experiments at the Swiss Light Source SLS and Switzerland's X-ray free-electron 
laser SwissFEL.

Further details:
Role:  Group Leader: Experiment IT Development and Operations
Closing Date: 10/10/21
https://www.psi.ch/en/pa/job-opportunities/47472-group-leader-experiment-it-development-and-operations

Please don't hesitate to contact me if you have any questions.

Other and similar roles at PSI available at: 
https://www.psi.ch/en/pa/job-opportunities
__
Dr Alun Ashton
Head of Science IT Infrastructure and Services (AWI) Department
Paul Scherrer Institut
WHGA/036
Forschungsstrasse 111
5232 Villigen PSI
Schweiz
Telefon: +41 56 310 44 81





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[ccp4bb] Vacancy: Software Scientist at PSI, Switzerland

2021-05-24 Thread Leonarski Filip (PSI)
Dear Colleagues,

At PSI we have an open position for a software scientist to work on a data 
acquisition pipeline for the cutting-edge PSI pixel-array detectors, producing 
20-100 GB/s of data, with a mix of high-end x86 servers and task-specific 
hardware architectures (IBM POWER, FPGA, GPU).

We are looking for a person with interest in strong C++ programming skills and 
emerging computing architectures. Prior experience with X-ray image acquisition 
is a strong advantage.

For more details see the advertisement on our web page:

https://www.psi.ch/en/pa/job-opportunities/45299-software-scientist

Closing date for applications is 13 June 2021.

Best regards,
Filip

Dr. Filip Leonarski
Beamline Data Scientist
Swiss Light Source
Paul Scherrer Institut
Tel: +41 56 310 5652



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[ccp4bb] Vacancy: Software Scientists to develop data reduction and processing solutions

2021-04-11 Thread Ashton Alun (PSI)
The SLS2.0 Software Development Team are looking for someone to join us and 
develop innovative data reduction and processing solutions for high data rate 
experiments.

More details below:
https://www.psi.ch/en/pa/job-opportunities/44635-software-scientist-data-processing

As either an enthusiastic and talented early career or experienced 
professional, you are motivated by interdisciplinary work at the interface 
between the physical sciences, data science, scientific software development 
and high-performance computing. You can demonstrate the ability to assimilate 
new ideas and turn them into practical, applied techniques and a willingness to 
continue to learn new developments. Given the data volumes and methodology 
being used, you have experience of managing and organizing the parameters and 
results of large datasets. You have significant experience of programming in 
languages extensively used in science (Python, C++) and of the development of 
software for deployment on on-premises or cloud-based compute clusters.

This position will offer you a great opportunity to develop your career in an 
exciting and highly multidisciplinary environment.
This is a fixed-term position. The employment contract will be limited to the 
duration of the SLS 2.0 upgrade project, which ends 31 December 2025.
For further information, please contact Dr Alun Ashton
Please submit your application online by 16 May 2021

__
Dr Alun Ashton, Head of Science IT
Paul Scherrer Institut
WHGA/036,  Forschungsstrasse
5232 Villigen, PSI, Switzerland
Phone: +41 56 310 4481




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[ccp4bb] vacancy posting

2021-04-05 Thread Chun-wa Chung
Title : Structural and Biophysical Scientist- GSK R&D, Stevenage,UK.
The posting for multiple talented laboratory-based scientists to join GSK's UK 
Structural & Biophysical Sciences group ends in a couple of days.
So if the opportunity to join a multi-disciplinary department to provide 
molecular insights into both small molecule and biopharmaceutical drug 
discovery excites you please do take a look.

https://gsk.wd5.myworkdayjobs.com/GSKCareers/job/UK---Hertfordshire---Stevenage/Structural-and-Biophysical-Scientist_280898-1
The application deadline is 7th April, 2021.
Best Wishes,
Chun-wa Chung
UK Head Structural & Biophysics  Sciences
GlaxoSmithKline R&D
Stevenage
SG1 2NY
 email : chun-wa.h.ch...@gsk.com



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[ccp4bb] Vacancy for an EMDB Coordinator at EMBL-EBI

2021-01-19 Thread Gerard Kleywegt


Are you an experienced electron microscopist who is passionate about cryo-EM 
and cryo-ET? Would you like to influence the way the world archives its EM 
data, including annotation, validation, dissemination, visualisation, etc.? Are 
you enthusiastic about engaging with the global EM community?


We are looking to recruit a Coordinator to lead the EMDB resource and 
activities at EMBL-EBI. This is a senior position, reporting directly to Dr 
Ardan Patwardhan who has overall responsibility for EMBL-EBI’s EM-archiving 
activities. It provides a rare and exciting opportunity for a motivated 
scientist with experience in this rapidly expanding and developing field to 
have a huge impact on how the scientific community archives, validates and 
re-uses EM data.


More information about the role, the requirements, the benefits of working at 
EMBL-EBI and the application procedure can be found at:


   https://www.embl.org/jobs/position/EBI01761/

If you know of any suitable candidates who might be interested in this 
position, please forward this mail to them. Thanks!


--Gerard

---
Gerard J. Kleywegt, EMBL-EBI, Hinxton, UK
Head of Molecular and  Cellular Structure
ger...@ebi.ac.uk pdbe.org emdb-empiar.org
PA: Roisin Dunloppdbe_ad...@ebi.ac.uk



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[ccp4bb] vacancy posting

2020-09-29 Thread Chun-wa Chung
Dear CCPEM and CPP4

Please could you arrange for the following vacancy to be posted onto your 
bulletin boards.
Many thanks
Chun-wa

Title : Cryo-EM protein biochemist and structural biologist - GSK R&D, 
Stevenage,UK.
We are currently expanding our CryoEM capability in Stevenage and recruiting 
for two positions.
If the opportunity to work towards medicines of the future excites you, then 
please take a look.
251927 CryoEM Protein Biochemist
https://gsk.wd5.myworkdayjobs.com/GSKCareers/job/UK---Hertfordshire---Stevenage/Protein-and-Cell-Science--CryoEM-Protein-BiochemistProtein-and-Cell-Science--CryoEM-Protein-Biochemist_251927-2

263553 CryoEM Structural Biologist
https://gsk.wd5.myworkdayjobs.com/GSKCareers/job/UK---Hertfordshire---Stevenage/Structural---Biophysical-Sciences---CryoEM-Structural-Biologist_263553-1
Application deadline is October 13th, 2019.
Best Wishes,
Chun-wa Chung
UK Head Structural & Biophysics  Sciences
GlaxoSmithKline R&D
Stevenage
SG1 2NY
 email : chun-wa.h.ch...@gsk.com



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[ccp4bb] Vacancy hiring: Postdoctoral Research Assistant in Protein Design and Synthetic Biology at University of Bristol

2020-09-22 Thread Fabio Parmeggiani
Research Assistant in Protein Design and Synthetic Biology
With Dr Fabio Parmeggiani, University of Bristol  

The group of Dr Fabio Parmeggiani is seeking a talented and enthusiastic 
postdoc interested in protein design and synthetic biology. The project will be 
focused on designing custom modular protein architectures as robust and 
reliable scaffolds for the development of novel functional protein-based 
nanomaterials and multivalent ligands to modulate cell response.

The aim of the project is to develop a robust, fast and high throughput design 
platform to rapidly build new proteins and complexes. The researcher will be 
responsible for developing the experimental part of the pipeline (involving DNA 
assembly, protein expression and purification, validation of designs through 
biophysical and structural characterization) and spearhead applications in 
nanomaterials and cell biology. The position would be best suited to a 
researcher with a keen interest in applying de novo protein design in synthetic 
biology. Essential skills for this role would include: design, construction and 
expression of synthetic genes in E. coli; biochemical and biophysical 
characterisation of proteins; strong structural biology expertise, in 
particular cryo-electron microscopy or x-ray crystallography.

Closing date:14 October 2020 

http://www.bristol.ac.uk/jobs/find/details.html?nPostingID=73754&nPostingTargetID=196714&option=28&sort=DESC&respnr=1&ID=Q50FK026203F3VBQBV7V77V83&LOV5=8070&LOV4=8100&LOV3=8492,8493&Resultsperpage=10&lg=UK&mask=uobext



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[ccp4bb] Vacancy: Software Developer For MX at Swiss Light Source, Switzerland

2020-09-21 Thread Wojdyla Justyna Aleksandra (PSI)
We are looking for a software developer to join macromolecular crystallography 
(MX) team to develop the next generation of data acquisition and analysis user 
software at the Swiss Light Source.

Further details and online application available here: 
https://www.psi.ch/en/pa/job-opportunities/39385-software-developer
Application Deadline: 18th of October 2020

Best regards,
Justyna

--
Dr Justyna Aleksandra Wojdyla
Group Leader MX Data
ad interim Industry Liaison Scientist
WSLA-222
Swiss Light Source
Forschungsstrasse 111
5232 Villigen-PSI
tel: +41 56 310 5428
e-mail: justyna.wojd...@psi.ch




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[ccp4bb] Vacancy: Software Scientist, (Data Acquisition) at PSI, Switzerland

2020-09-18 Thread Ashton Alun (PSI)
We have a new opportunity for someone to join PSI and help (or lead if 
experience allows) develop and direct the future direction, design, 
implementation and eventual support for a standard environment for end 
station/experiment control at the Swiss Light Source SLS and its future upgrade 
SLS2.0.

Further details available at:
https://www.psi.ch/en/pa/job-opportunities/39346-software-scientist-data-acquisition
Application Deadline: 18 October 2020

Please don't hesitate to contact me if you have any questions.

Other roles at PSI available at: https://www.psi.ch/en/pa/job-opportunities

Regards,
Alun
__
Dr Alun Ashton, Head of Science IT
Paul Scherrer Institut
WHGA/036,  Forschungsstrasse
5232 Villigen, PSI, Switzerland
Phone: +41 56 310 4481





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[ccp4bb] Vacancy: Software Scientist, Machine Learning at PSI, Switzerland

2020-08-09 Thread Ashton Alun William (PSI)
We have a new opportunity for someone to work on the REDML project to reduce 
high volume experimental data using machine learning as part of an initiative 
between the Swiss Data Science Center, the Swiss National Supercomputing Center 
and the Paul Scherrer Institut.

The role will be centered on science use cases, the first of which will be the 
real time reduction of diffraction data directly from detectors. The goal of 
this usecase would be the eventual reduction of raw data with the appliation of 
ML that will surpas current algorithms in both accuracy and speed.

Further details available at:
https://www.psi.ch/en/pa/job-opportunities/35141-software-scientist-machine-learning
Application Deadline: 23 August 2020

Regards,
Alun
__
Dr Alun Ashton, Head of Science IT
Paul Scherrer Institut
WHGA/036,  Forschungsstrasse
5232 Villigen, PSI, Switzerland
Phone: +41 56 310 4481





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[ccp4bb] Vacancy in R&D Thermo Fisher, Eindhoven The Netherlands

2019-08-20 Thread Kuijper, Maarten
At Thermo Fisher Scientific, located in Eindhoven The Netherlands, we have a 
new vacancy in our New Product Development (R&D) team: 'CryoEM Sample Prep - 
Project Manager'.

Our team is pursuing improvements in efficiency, effectiveness and reliability 
of the sample creation process for Cryo-EM.



As project manager for Sample Preparation you will lead multiple projects 
enabling workflow solutions, in your case this will focus around sample 
preparation.



Next to project management skills, the successful candidate should have a 
background in biochemistry and sample preparation protocols of biological 
specimen for structural analysis. Hands on in CryoEM is a plus.



For further particulars and to apply for these posts, please follow



CryoEM Sample Prep - Project Manager: 
https://jobs.thermofisher.com/ShowJob/Id/723744/CryoEM-Sample-Prep-Project-Manager/







Regards,

Maarten Kuijper

Workflow Architect, Research and Development

Thermo Fisher Scientific





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[ccp4bb] Vacancy - Teaching Fellow in Structural Biology & Biochemistry, Portsmouth, UK

2019-07-05 Thread John McGeehan
Dear Colleagues,

We have a new 3 year Teaching Fellow / Senior Teaching Fellow position in
the School of Biological Sciences at the University of Portsmouth, UK.

In light of recent research success securing £5.8 million to create the Centre
for Enzyme Innovation
,
the School of Biological Sciences
 is seeking to
appoint a committed individual to a full time Teaching Fellow / Senior
Teaching Fellow in the area of structural biology and biochemistry on a
three year fixed term contract. The Department is based within the Faculty
of Science and holds strong teaching and research links. The Department
performed very well in the Research Excellence Framework (REF2014), is
ranked 3rd among the Alliance group in this subject area (UoA3) and
reported 90% of its research as being world leading or internationally
excellent. The department is well regarded as shown in league tables (3rd
in the Guardian league table) and has good student satisfaction in this
subject area. At an institutional level, we have recently been awarded Gold
standard in the Teaching Excellence Framework.

The successful candidate will contribute to the teaching in the area of
structural biology and biochemistry and also to the general teaching
activities and pastoral care at foundation, undergraduate and postgraduate
level. In addition to holding a PhD and having published in relevant
peer-review journals, it is essential that the appointee is able to
demonstrate experience of teaching in the broad area of biochemistry and
structural biology.


Teaching Fellow: *£35,211 - £38,460 per annum *
Senior Teaching Fellow: *£39,609 - £48,677 per annum  *
Closing date: * 17 July 2019 *
Interview date:  *25 July 2019*

For detailed information about the vacancy, please select this link: ZZ005416
- Teaching Fellow or Senior Teaching Fellow in Structural Biology and
Biochemistry.docx

or contact Dr Darren Mernagh (Head of Department) via
email:darren.mern...@port.ac.uk

Applications can be made on our recruitment website

.

Best Regards,
John
-- 
*Professor John McGeehan*
--
Director, Centre for Enzyme Innovation (web
),
Institute of Biological and Biomedical Sciences (web
),
School of Biological Sciences,
University of Portsmouth,
King Henry Building,
PO1 2DY, UK
--
Email: john.mcgee...@port.ac.uk
Tel:+44 (0) 2392 842042
*PA: Jacky Dillon *
Email: jacky.dil...@port.ac.uk
Tel: +44 (0) 23 92842023

- *An interview with the BBSRC, 2019*  -



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[ccp4bb] Vacancy at Diamond: Senior Support Scientist (I04-1, XChem)

2018-07-25 Thread Frank von Delft

Hello all

I'm recruiting a Senior Support Scientist to my beamline I04-1 at 
Diamond.  Apart from MX user support (obviously), the position will help 
work on automating more complicated kinds of data collection and 
figuring out how to get more data faster, especially for XChem fragment 
screening but also beyond.


Technically-minded crystallographers that enjoy teaching or training 
people, but also like hands-on wires-and-cables style work and/or 
mucking around with programming or scripting, will enjoy this job. 
Diamond is incredibly collegial, with a terrific user community.


The ad is here:
https://vacancies.diamond.ac.uk/vacancy/senior-support-scientist-356961.html

Frank


--
Prof Frank von Delft

Principal Beamline Scientist: I04-1
Diamond Light Source
+44 1235 778997 (office: M,T,T)
+44 7471 026103 (mobile)

Associate Professor Principal Investigator: Protein Crystallography
Structural Genomics Consortium
Oxford University
+44 1865 617583 (office: W,F)



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[ccp4bb] Vacancy at Evotec UK (Abingdon)

2018-07-11 Thread Matthias Zebisch
Dear All,

There is an opportunity to join the Structural Biology team at Evotec based in 
the UK as a Senior Scientist (Protein purification). Please see the advert in 
the link below. Interested candidates should apply directly through our 
website. Please do not send applications through to me directly. Closing date 
is July 31st and applicants must be eligible to work in UK. The position is for 
a 12 month contract.

https://recruitment.evotec.com/VacancyDetails.aspx?FromSearch=True&MenuID=QSAukis1tlc=&VacancyID=649


Best wishes,

Matthias





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[ccp4bb] Vacancy@the SPC Facility, EMBL Hamburg Unit

2018-05-25 Thread Margret Fischer

Dear colleagues,

I would like to inform you that EMBL Hamburg is currently advertising 
for a Scientific Officer for the Sample Preparation & Characterization 
(SPC).
The facility supports external researchers carrying out experiments on 3 
EMBL beamlines ( 2x MX and 1 SAXS). An extension of the SPC activities
is hosted in the new Centre for Structural Systems Biology (CSSB).The 
Scientific Officer – Biophysical Characterization will support users 
with the design,

execution and data analysis of biophysical experiments.

The facility currently covers a broad range of biophysical techniques, 
including calorimetry, mass spectroscopy, circular dichroism, 
fluorescence, microscale
thermophoresis, dynamic/static light scattering, infrared spectroscopy, 
surface plasmon resonance and biolayer Interferometry. The postholder 
will be responsible for
the maintenance and operation of biophysical instruments as well as for 
training users to operate the equipment independently. He/She will have an
opportunity to develop own relevant research activities within the 
framework of the group by Maria Garcia Alai related to the development 
of new methods at the SPC.


Deadline for application is the 1st July 2018

More detailed information can be found here: http://s.embl.org/HH00140

best wishes,

Margret
--

Margret Fischer
European Molecular Biology Laboratory
Senior Administrative Officer
Notkestrasse 85
22607 Hamburg
Germany
Tel: +49 40 89902110
Mob: +49 1754105760


[ccp4bb] Vacancy for Post-doctoral Researcher at VUB, Brussels

2018-04-11 Thread David Young
Dear all,

I would like to draw your attention to an immediately available position as a 
post-doctoral researcher in the Redox Signaling Laboratory, Vrije Universiteit 
Brussel (VUB), Belgium (for more lab info see 
http://www.vib.be/en/research/scientists/Pages/Joris-Messens-Lab.aspx).
We are looking for a candidate either with a strong background in both enzyme 
kinetics and structural biology/biophysics, or someone experienced in enzyme 
kinetics who also has interest in learning structural biology techniques.
For more information, see attached job advertisement.
Potential candidates should contact Prof. J. Messens directly with CV and Cover 
Letter to joris.mess...@vub.be
Best wishes,

David Young


vacature kinetics_final.docx
Description: MS-Word 2007 document


[ccp4bb] Vacancy for scientific data curator (EMDB/EMPIAR) at EMBL-EBI

2018-02-16 Thread Ardan Patwardhan
Dear all

We are looking to recruit an expert structural biologist with cryo-EM 
experience as a Scientific Data Curator for EMDB and EMPIAR. 

The post holder will work with the annotation and biocuration of the EMDB and 
EMPIAR archives. The biocuration activity with also involve improving the 
integration of EMDB and EMPIAR data with other bioinformatics resources. In 
order to make resources more accessible to a wide spectrum of biomedical users 
the post holder will also help with user-experience (UX) testing, outreach and 
training.

For more information, please go to:

https://www.embl.de/jobs/searchjobs/index.php?ref=EBI_01149&newlang=1 



Feel free to pass the information on to any potentially interested and 
qualified people you may know.

Many thanks and best wishes

Ardan Patwardhan
Team Leader - Cellular Structure & 3D Bioimaging
EMDB & EMPIAR
European Bioinformatics Institute (EMBL-EBI) European Molecular Biology 
Laboratory
Wellcome Genome Campus
Hinxton, Cambridge CB10 1SD
Tel: +44 1223 492649

[ccp4bb] Vacancy for a Science Technician in Protein Crystallography and Biophysical Analysis at JIC, Norwich, UK

2018-01-26 Thread clare stevenson (JIC)
Dear All,
I would like to draw your attention to an open position for a science 
technician supporting the protein crystallography and biophysical analysis 
facilities at the John Innes Centre in Norwich, UK.
Details about the position (deadline for application: 16 Feb 2018) can be found 
here:
https://www.jic.ac.uk/training-careers/vacancies/2018/01/science-technician-protein-crystallography-and-bio/

Informal enquiries about the position can be addressed to 
nbi.recruitm...@nbi.ac.uk  (quoting reference 1003404) or 
clare.steven...@jic.ac.uk

Best wishes,
Clare


Science Technician (Protein Crystallography and Biophysical Analysis Facilities)

Applications are invited for an enthusiastic and motivated individual to join 
the John Innes Centre as a Science Technician supporting our Protein 
Crystallography and Biophysical Analysis facilities.

Background:

The John Innes Centre is an independent, international centre of excellence in 
plant and microbial sciences.

The Protein X-ray Crystallography (PX) facility provides services and expertise 
for the determination of the three-dimensional structures of proteins of 
interest. The Biophysical Analysis (BA) facility provides services and 
expertise to study important biomolecular interactions using the techniques of 
Surface Plasmon Resonance and Isothermal Titration Calorimetry. Together these 
facilities provide deep insights into molecular interactions, gene regulation, 
enzyme mechanism, protein function and protein evolution.

The role:

We are seeking a science technician to support the work of the protein 
crystallography (PX) and biophysical analysis (BA) facilities. 70% of the time 
would be spent supporting the PX facility and 30% supporting the BA facility. 
The major responsibilities would include looking after specialist lab 
equipment, replenishing laboratory stocks, and liaising with users of the 
facilities to ensure that the service delivered is of excellent scientific 
quality.

The ideal candidate:

We are keen to employ an enthusiastic person with proven laboratory skills who 
is eager to work on a scientific facility providing excellent expertise and 
services to both internal and external users. Candidates should possess a BSc 
or equivalent in a biological subject, or possess significant relevant 
experience of working in a laboratory setting.

The candidate must to be able to work independently, have excellent 
organisational skills and good oral and written communication skills. The 
ability to act quickly to give advice or troubleshoot any issues is also very 
important. The ability to work occasional unsociable hours is also required.

Additional information:

Salary on appointment will be within the range £24,300 to £29,750 per annum 
depending on qualifications and experience.  This post is for an initial 
contract of three years.

We welcome applications from candidates seeking job-share, part-time or other 
flexible working arrangements.

For further information and details of how to apply, please visit our web site 
http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or 
nbi.recruitm...@nbi.ac.uk  quoting reference 1003404.

We are an equal opportunities employer, actively supporting inclusivity and 
diversity.  As a Disability Confident organisation, we guarantee to offer an 
interview to all disabled applicants who meet the essential criteria for this 
vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena 
SWAN and is a member of Stonewall's Diversity Champions programme.

The closing date for applications will be 16th Feb

For informal inquires feel free to contact 
clare.steven...@jic.ac.uk


Dr Clare E.M. Stevenson
John Innes Centre
Norwich Research Park
Colney Lane
Norwich
NR4 7UH
Tel 01603 450734



[ccp4bb] vacancy for structural biology research technician/assoc. at Diamond/Research Complex at Harwell **deadline 27th August*** interviews 11th Sept

2017-08-11 Thread Martin Walsh
Dear all we have a vacancy for a structural biology research tech/assoc – great 
opportunity to be embedded in research work at diamond/research complex

Hot tip for UK based people interested …get your applications in before you go 
off and enjoy your bank holiday weekend!interviews scheduled for 11th  
September.

Details in link below:

http://www.diamond.ac.uk/Careers/Vacancies/All/089_17_CH.html

Martin

--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


-- 
This e-mail and any attachments may contain confidential, copyright and or 
privileged material, and are for the use of the intended addressee only. If you 
are not the intended addressee or an authorised recipient of the addressee 
please notify us of receipt by returning the e-mail and do not use, copy, 
retain, distribute or disclose the information in or attached to the e-mail.
Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 
Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments 
are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.
Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom


[ccp4bb] vacancy structural biologist/biophysicist faculty

2017-08-11 Thread Elias Fernandez




ASSISTANT/ASSOCIATE PROFESSOR POSITION IN EXPERIMENTAL

BIOPHYSICS/STRUCTURAL BIOLOGY AT THE UNIVERSITY OF TENNESSEE



The Department of Biochemistry & Cellular and Molecular Biology (BCMB) at
the University of Tennessee, Knoxville (UT) is soliciting applications for a
tenure‐track position at the rank of an Assistant or Associate Professor to
begin on August 1, 2018. BCMB (https://bcmb.utk.edu) has 40 active faculty
with core strengths in experimental and computational structural
biochemistry & biophysics, plant/microbial biology, and developmental
genetics. We seek applicants who use experimental structural or biophysical
approaches to study complex cellular, sub‐cellular, or molecular systems.



Assistant professors will be required to develop an innovative and
extramurally funded research program that complements existing areas of
research within the BCMB Department. Associate Professors will be expected
to have established and well-funded research programs. UT is located near
the Oak Ridge National Laboratory (ORNL) and candidates interested in
developing collaborative research programs with ORNL are encouraged to
apply. The successful candidate will benefit greatly from available
computational resources, the on-campus National Institute for Mathematical
and Biological Synthesis (NIMBioS) and the UT-ORNL Joint Institutes for
Computational Sciences, Biological Sciences, Advanced Materials, and Neutron
Sciences.  The Knoxville campus of the University of Tennessee is seeking a
candidate who has the ability to contribute in meaningful ways to the
diversity and intercultural goals of the University.



Applicants must have a doctorate (PhD or equivalent) and postdoctoral
experience in an appropriate discipline with evidence of high quality
research. Also important, is an interest in teaching biochemistry and/or
physical biochemistry at both the undergraduate and graduate levels.



Applicants must send a single document containing a cover letter, CV with a
full list of publications, statements of current and future research
interests, and of teaching philosophy in PDF format to
 experimentalbiophys...@utk.edu.
Applicants must also arrange to have at least three letters of
recommendation sent electronically to  
utkreferen...@utk.edu. The review of applications will begin in October 16,
2017, and will continue until the position is filled.





The University of Tennessee is an EEO/AA/Title VI/Title IX/Section
504/ADA/ADEA institution

in the provision of its education and employment programs and services.  All
qualified applicants will receive equal consideration for employment without
regard to race, color, national origin, religion, sex, pregnancy, marital
status, sexual orientation, gender identity, age, physical or mental
disability, or covered veteran status.







Re: [ccp4bb] Vacancy: structural biologist with cryo-EM expertise at GSK closing date 24th March

2017-03-10 Thread Anindito Sen
Apologies to you All.

The email got copied to every one. In any case its a junk for rest of you. 
Kindly delete it, if you can.


Best Regards

Andy



Anindito Sen. Ph.D
> On Mar 10, 2017, at 9:17 PM, Vellieux Frédéric  
> wrote:
> 
> Hello,
> 
> I am not “Dr Chung” and I haven’t received anything from you. Sorry to 
> disappoint you.
>  
> Perhaps a “reply all” isn’t appropriate when replying to a ccp4bb message ? I 
> let you be the judge on that…
>  
> Fred.
>  
> From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK 
> <mailto:CCP4BB@JISCMAIL.AC.UK>] On Behalf Of Anindito Sen
> Sent: Friday, March 10, 2017 12:53 PM
> To: CCP4BB@JISCMAIL.AC.UK <mailto:CCP4BB@JISCMAIL.AC.UK>
> Subject: Re: [ccp4bb] Vacancy: structural biologist with cryo-EM expertise at 
> GSK closing date 24th March
>  
> Hello Dr. Chung,
>  
> It was nice talking to you. I have submitted the application online. However 
> I have not received any email conformation. In any case, I am attaching the 
> screenshot of my submission below.
>  
> Kindly acknowledge when you receive my application. 
>  
> Best Regards
>  
> Andy
>  
>  
>  
>  
> 
>  
> Anindito Sen. Ph.D
> Scientist and Application Specialist in Biological Sciences
> JEOL LTD.
> 13F, Ohtemachi Nomura Bldg.
> 2-1-1 Ohtemachi, Chiyoda-ku, Tokyo
> 100-0004
> Tel: +81-3-62623563
> Fax: +81-3-6262-3577
> 
> www.jeol.com <http://www.jeol.com/>
>  
> On Mar 6, 2017, at 7:03 PM, Chun-wa Chung  <mailto:chun-wa.h.ch...@gsk.com>> wrote:
>  
> Job-posting  - Seeking structural biologist with cryo-EM expertise at GSK
>  
> A vacancy for a structural biologist with cryo-EM expertise has opened up 
> within the UK structural and biophysical sciences group at GlaxoSmithKline 
> R&D. Joining an experienced multi-disciplinary group, this is an exciting 
> opportunity for a motivated individual to complement and help shape our 
> current capabilities in the EM area. 
> This is a permanent, full-time position suitable for a PhD degree holder (or 
> equivalent).
> 
> To apply for this role and for further details, please click on the link 
> below (Vacancy no : WD106591) 
> https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=330903&localeCode=en-us
>  
> <https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=330903&localeCode=en-us>
> A full job description is also included at the end of this message.
> 
> Applications for this vacancy are to be made online by 24th MARCH
> Informal inquiries can be sent to  chun-wa.h.ch...@gsk.com 
> <mailto:chun-wa.h.ch...@gsk.com>
> Thank you for your interest,  
> 
> Chun-wa Chung
> 
> UK Head Structural & Biophysics  Sciences
> GlaxoSmithKline R&D
> Stevenage
> SG1 2NY
> Tel no: +44 1438 763342
> email : chun-wa.h.ch...@gsk.com <mailto:chun-wa.h.ch...@gsk.com>
>  
>  
>  
> Full Job Description (WD78277):
> GlaxoSmithKline is a world leading research-based pharmaceutical company. We 
> are focused around three core businesses: Pharmaceuticals, Vaccines and GSK 
> Consumer Healthcare. We have a significant global presence with commercial 
> operations in more than 150 countries, a network of 84 manufacturing sites in 
> 36 countries and large R&D centres in the UK, US,  Belgium and China.
> The UK Structural and Biophysical Sciences group is a multi-disciplinary 
> department within GSK R&D that provides molecular insights into drug 
> discovery for both small molecule and biopharmaceutical programs.
> 
> We currently have an exciting opportunity for a laboratory-based scientist 
> with expertise in state-of-the-art electron microscopy techniques to play an 
> influential and key role in the application and development of these methods 
> across small molecule and therapeutic protein programs. This individual will 
> have extensive experience in the sample preparation and optimisation 
> processes necessary to produce high-quality molecular images of protein 
> structure, including direct experience of Cryo-EM methodologies. Experience 
> of data analysis and interpretation is also expected. Being responsible for 
> delivering structural insights to support program teams and contributing to 
> the  wider protein structural and biophysical area by identifying and driving 
> forward improvements and innovations that advance drug discovery projects, 
> the individual must be a collaborative team player able to work successfully 
> with other scientists within the department and within diverse teams.
> 
> Key Responsibilities and Accountabi

Re: [ccp4bb] Vacancy: structural biologist with cryo-EM expertise at GSK closing date 24th March

2017-03-10 Thread Anindito Sen
Hello Dr. Chung,

It was nice talking to you. I have submitted the application online. However I 
have not received any email conformation. In any case, I am attaching the 
screenshot of my submission below.

Kindly acknowledge when you receive my application. 

Best Regards

Andy






Anindito Sen. Ph.D
Scientist and Application Specialist in Biological Sciences
JEOL LTD.
13F, Ohtemachi Nomura Bldg.
2-1-1 Ohtemachi, Chiyoda-ku, Tokyo
100-0004
Tel: +81-3-62623563
Fax: +81-3-6262-3577

www.jeol.com

> On Mar 6, 2017, at 7:03 PM, Chun-wa Chung  wrote:
> 
> Job-posting  - Seeking structural biologist with cryo-EM expertise at GSK
>  
> A vacancy for a structural biologist with cryo-EM expertise has opened up 
> within the UK structural and biophysical sciences group at GlaxoSmithKline 
> R&D. Joining an experienced multi-disciplinary group, this is an exciting 
> opportunity for a motivated individual to complement and help shape our 
> current capabilities in the EM area. 
> This is a permanent, full-time position suitable for a PhD degree holder (or 
> equivalent).
> 
> To apply for this role and for further details, please click on the link 
> below (Vacancy no : WD106591) 
> https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=330903&localeCode=en-us
>  
> 
> A full job description is also included at the end of this message.
> 
> Applications for this vacancy are to be made online by 24th MARCH
> Informal inquiries can be sent to  chun-wa.h.ch...@gsk.com 
> 
> Thank you for your interest,  
> 
> Chun-wa Chung
> 
> UK Head Structural & Biophysics  Sciences
> GlaxoSmithKline R&D
> Stevenage
> SG1 2NY
> Tel no: +44 1438 763342
> email : chun-wa.h.ch...@gsk.com 
>  
>  
>  
> Full Job Description (WD78277):
> GlaxoSmithKline is a world leading research-based pharmaceutical company. We 
> are focused around three core businesses: Pharmaceuticals, Vaccines and GSK 
> Consumer Healthcare. We have a significant global presence with commercial 
> operations in more than 150 countries, a network of 84 manufacturing sites in 
> 36 countries and large R&D centres in the UK, US,  Belgium and China.
> The UK Structural and Biophysical Sciences group is a multi-disciplinary 
> department within GSK R&D that provides molecular insights into drug 
> discovery for both small molecule and biopharmaceutical programs.
> 
> We currently have an exciting opportunity for a laboratory-based scientist 
> with expertise in state-of-the-art electron microscopy techniques to play an 
> influential and key role in the application and development of these methods 
> across small molecule and therapeutic protein programs. This individual will 
> have extensive experience in the sample preparation and optimisation 
> processes necessary to produce high-quality molecular images of protein 
> structure, including direct experience of Cryo-EM methodologies. Experience 
> of data analysis and interpretation is also expected. Being responsible for 
> delivering structural insights to support program teams and contributing to 
> the  wider protein structural and biophysical area by identifying and driving 
> forward improvements and innovations that advance drug discovery projects, 
> the individual must be a collaborative team player able to work successfully 
> with other scientists within the department and within diverse teams.
> 
> Key Responsibilities and Accountabilities: 
> • Design and perform technical experiments in the EM area (sample 
> preparation, optimisation and analysis).
> • Document and communicate scientific results clearly and promptly.
> • Provide strong scientific lead to shape EM strategy within structural 
> biology and across therapeutic discovery programs.
> • Build EM capabilities and infrastructure through interactions with the 
> internal and external scientific community.
> • Maintain scientific excellence and lead in a rapidly evolving area e.g. 
> through interactions such as the FEI/LMB/Pharm consortium.
> • Become an integral team member of multiple project teams.
> 
> Key Capabilities and Proficiency:
> 1. Technical expertise leading to Impact 
> Evidence of specific and in depth knowledge of transmission electron 
> microscopy used as a structural technique, especially single particle 
> cryo-EM. A track record of its application to address scientific problems 
> relevant to pharmaceutical research. 
> 2. Influence and Scientific awareness 
> Evidence of engagement with external scientific environment including the 
> ability to identify and pursue opportunities that advance capabilities within 
> own research area.
> 3. Team work 
> Demonstrable ability to both directly and indirectly influence and impact the 
> progression of programs of res

[ccp4bb] Vacancy: structural biologist with cryo-EM expertise at GSK closing date 24th March

2017-03-06 Thread Chun-wa Chung
Job-posting  - Seeking structural biologist with cryo-EM expertise at GSK

A vacancy for a structural biologist with cryo-EM expertise has opened up 
within the UK structural and biophysical sciences group at GlaxoSmithKline R&D. 
Joining an experienced multi-disciplinary group, this is an exciting 
opportunity for a motivated individual to complement and help shape our current 
capabilities in the EM area.
This is a permanent, full-time position suitable for a PhD degree holder (or 
equivalent).
To apply for this role and for further details, please click on the link below 
(Vacancy no : WD106591) 
https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=330903&localeCode=en-us
A full job description is also included at the end of this message.
Applications for this vacancy are to be made online by 24th MARCH
Informal inquiries can be sent to  
chun-wa.h.ch...@gsk.com
Thank you for your interest,
Chun-wa Chung
UK Head Structural & Biophysics  Sciences
GlaxoSmithKline R&D
Stevenage
SG1 2NY
Tel no: +44 1438 763342
email : chun-wa.h.ch...@gsk.com





Full Job Description (WD78277):

GlaxoSmithKline is a world leading research-based pharmaceutical company. We 
are focused around three core businesses: Pharmaceuticals, Vaccines and GSK 
Consumer Healthcare. We have a significant global presence with commercial 
operations in more than 150 countries, a network of 84 manufacturing sites in 
36 countries and large R&D centres in the UK, US,  Belgium and China.
The UK Structural and Biophysical Sciences group is a multi-disciplinary 
department within GSK R&D that provides molecular insights into drug discovery 
for both small molecule and biopharmaceutical programs.

We currently have an exciting opportunity for a laboratory-based scientist with 
expertise in state-of-the-art electron microscopy techniques to play an 
influential and key role in the application and development of these methods 
across small molecule and therapeutic protein programs. This individual will 
have extensive experience in the sample preparation and optimisation processes 
necessary to produce high-quality molecular images of protein structure, 
including direct experience of Cryo-EM methodologies. Experience of data 
analysis and interpretation is also expected. Being responsible for delivering 
structural insights to support program teams and contributing to the  wider 
protein structural and biophysical area by identifying and driving forward 
improvements and innovations that advance drug discovery projects, the 
individual must be a collaborative team player able to work successfully with 
other scientists within the department and within diverse teams.

Key Responsibilities and Accountabilities:
* Design and perform technical experiments in the EM area (sample preparation, 
optimisation and analysis).
* Document and communicate scientific results clearly and promptly.
* Provide strong scientific lead to shape EM strategy within structural biology 
and across therapeutic discovery programs.
* Build EM capabilities and infrastructure through interactions with the 
internal and external scientific community.
* Maintain scientific excellence and lead in a rapidly evolving area e.g. 
through interactions such as the FEI/LMB/Pharm consortium.
* Become an integral team member of multiple project teams.

Key Capabilities and Proficiency:
1. Technical expertise leading to Impact
Evidence of specific and in depth knowledge of transmission electron microscopy 
used as a structural technique, especially single particle cryo-EM. A track 
record of its application to address scientific problems relevant to 
pharmaceutical research.
2. Influence and Scientific awareness
Evidence of engagement with external scientific environment including the 
ability to identify and pursue opportunities that advance capabilities within 
own research area.
3. Team work
Demonstrable ability to both directly and indirectly influence and impact the 
progression of programs of research and to work in multi-disciplinary teams, 
displaying appropriate interpersonal skills and team work






This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.


[ccp4bb] Vacancy at PDBe for an experienced scientific programmer (validation and structure analysis)

2015-05-29 Thread Gerard DVD Kleywegt

Dear CCP4BB-ers,

The Protein Data Bank in Europe (PDBe; http://pdbe.org/) is urgently seeking 
to recruit an experienced scientific programmer to develop and maintain 
validation and analysis tools for biomacromolecular structure data. Applicants 
should ideally be established structural biologists with a proven track record 
in methods/software development in the area of protein-ligand crystallography, 
validation and structure analysis, and with an outstanding publication record.


The post holder will be responsible for:

- Developing and maintaining the wwPDB validation pipelines, used during and 
prior to structure deposition and after structure release, using input from 
the wwPDB Validation Task Forces and the PDBe Team Leader.


- Developing and maintaining structure analysis and comparison tools such as 
PDBePISA and PDBeFold.


- Developing innovative tools to present structural data and validation 
information on biomacromolecules and ligands.


- Working with other PDBe staff to integrate validation information into the 
PDBe query system and the PDB and EMDB entry pages.


- Acting as a source of expertise to the PDBe team on issues of validation and 
ligands (in the context of deposition, annotation, databases and services).


Note: in order to have overlap with the current post-holder we aim for a 
starting date no later than 1 July.


For more information about the post, see: 
https://ig14.i-grasp.com/fe/tpl_embl01.asp?newms=jj&id=53803&aid=15470


Please feel free to pass on this information to any potentially suitable 
candidates you may be aware of.


Thanks!

--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy for a scientific database curator at PDBe

2015-03-26 Thread Gerard DVD Kleywegt

Hi all,

We are looking to recruit an expert structural biologist (with experience in 
structure determination) to join the Protein Data Bank in Europe curation team 
(PDBe: pdbe.org) at the European Bioinformatics Institute (EMBL-EBI, 
Cambridge, UK) as a Scientific Database Curator. The work involves annotating 
preliminary PDB and Electron Microscopy Data Bank (EMDB) submissions and 
extracting relevant biological information. In addition, curators contribute 
to training, outreach and user-support activities of PDBe and the EMBL-EBI.


For more information, please go to:

   http://www.embl.de/jobs/searchjobs/index.php?newlang=1&ref=EBI_00522

Feel free to pass the information on to any potentially interested and 
qualified people you may know.


Thanks!

--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy for a Scientific Programmer Bioimaging & EMPIAR at PDBe

2015-03-17 Thread Gerard DVD Kleywegt

Hi all,

We are looking to recruit an experienced and motivated "Scientific Programmer 
Bioimaging & EMPIAR" to join the Protein Data Bank in Europe (PDBe) team at 
the European Bioinformatics Institute (EBI) located on the Wellcome Trust 
Genome Campus near Cambridge in the UK.


PDBe has recently launched EMPIAR (http://pdbe.org/empiar), an archive of raw 
2D image data from electron microscopy and electron tomography experiments. We 
now plan to extend and improve the archival, integration and dissemination of 
cellular imaging data from a range of other modalities including 3D scanning 
electron microscopy (3D-SEM), soft X-ray tomography (SXT) and correlative 
light and electron microscopy (CLEM). We are therefore seeking to recruit an 
enthusiastic scientific programmer with outstanding programming skills to join 
the EMPIAR development team.


For more information, see:

 https://ig14.i-grasp.com/fe/tpl_embl01.asp?newms=jj&id=53570&aid=15470

For informal enquiries, please contact Ardan Patwardhan , who 
is in charge of the EMPIAR project.


Best wishes,

--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy for a Faculty Position in the Department of Biophysics, NIMHANS, Bangalore, India

2014-12-22 Thread Padmanabhan B
A vacancy for a Faculty Position (Assistant Professor) in the Department of
Biophysics, National Institute of Mental Health and Neuro Sciences
(NIMHANS), Bangalore, INDIA.
Research experience in neuroscience/membrane proteins.
Here is the link to the advertisement:
http://www.nimhans.kar.nic.in/notifications.htm

The last date for submitting the Application: *19 Jan 2015*

Please forward to interested candidates. Thanks you.

-B. Padmanabhan

*
B. Padmanabhan, Ph. D
Additional Professor
Department of Biophysics
NIMHANS
Bangalore - 560029
INDIA


[ccp4bb] Vacancy for a Computational Structural Biologists: Aliso Viejo, Ca, USA

2014-12-18 Thread Robert Huether
Dear All,

Please see the position below.

Thanks,

Role and Responsibilities:
We are seeking a highly motivated scientist in computational structural 
bioinformatics to further expand our current in house-structural database and 
develop new methods and protocols for structural modeling, structural dynamics, 
protein-protein binding and variant analysis. The main responsibilities include 
analyzing and interpreting structure-function relationships, supporting the 
clinical reporting team and assisting R&D in developing new assays. The 
candidate must be currently living in USA. For more information see 
http://ambrygen.com/careers/structural-biologist

Education and Experience Requirements:
Education and Experience Requirements:
*PhD in Computational Structural Biology, Biophysics, Biochemistry or a closely 
related field.
*Candidates must have a thorough and ongoing knowledge of current theories and 
principals of computational structural biology (bimolecular modeling and 
dynamics).
*Experience in programming (Perl, Python, R, bash, C/C++, java) and databases 
in Linux/Unix environment.
*Knowledge of human genetics, statistics, bioinformatics databases, and 
computational tools in membrane protein analysis are preferred.
*You must have excellent time management as well as oral and written 
communication skills.
*Ability to quickly and effectively operate, communicate and influence decision 
making within cross-functional and multi-disciplinary clinical genetics team.

Ambry Genetics (www.ambrygen.com) offers a competitive 
salary commensurate with experience and qualifications. Benefits include 
health, dental, vision, 401K, 125c, generous PTO package, high-performance 
culture, supplemental insurance (i.e. Pet, Legal, Aflac, etc.), relocation 
allowance, and 125c.

Interested candidates should submit a letter of interest, working permission 
status, available date, and curriculum vitae to: 
h...@ambrygen.com


Robert Huether, PhD

Structural Biologist

Ambry Genetics
Direct 949.457.4367
rhuet...@ambrygen.com
www.AmbryGen.com


[http://www.ambrygen.com/resources/signature/logo.png]


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the sole use of the intended recipient(s) and may contain confidential and  
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[ccp4bb] Vacancy for a web-developer at PDBe

2014-12-17 Thread Gerard DVD Kleywegt

Hi all,

We are looking to recruit an experienced Web Front-End Developer with an 
interest in biological data to work within the Protein Data Bank in Europe 
team (PDBe; pdbe.org) at the European Bioinformatics Institute (EMBL-EBI) in 
Cambridge (UK).


For more information, please surf to:

   http://ig14.i-grasp.com//fe/tpl_embl01.asp?newms=jj&id=53259&aid=15470

Feel free to pass the information on to any potentially interested and 
qualified people you may know.


Thanks!

--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy

2014-10-17 Thread F.Xavier Gomis-Rüth

*/Laboratory Technician in biochemistry/molecular biology/*

A part-time position (50%) for a laboratory technician at FPII level or 
similar (Grupo Profesional 4 of CSIC) is available to work in the 
Structural MitoLab of the Molecular Biology Institute of Barcelona 
(IBMB) from the Spanish Research Council (CSIC) in Barcelona (Spain).The 
IBMB is located within the premises of the Barcelona Science Park (PCB), 
one of the two major poles for excellence in biosciences in the 
Barcelona area.


Applications are invited from candidates with proven expertise in all 
techniques associated with management and support tasks of a molecular 
biology laboratory. The candidate must be self-motivated and dedicated, 
be able to work independently but also to synergetically interact with 
other lab members, and have at least a basic level in English, spoken 
and written. The tentative starting date would be in January, 2015.


Interested persons should apply exclusively per e-mail and send a 
detailed CV, as well as a covering letter including motivation, details 
on their expertise in protein production, and contact details of three 
referees to Maria Solà (msv...@ibmb.csic.es ).


Relevant links:

Structural MitoLab:www.ibmb.csic.es/home/msola

PCB:www.pcb.ub.es/homePCB/live/en/p1.asp 



Barcelona city:www.bcn.cat/en/ihome.htm 




[ccp4bb] Vacancy: Professor for Biophysics at University of Konstanz

2013-08-14 Thread Kay Diederichs

Hi everybody,

I would like to bring to your attention the following job offer:
==

The University of Konstanz with its “Institutional Strategy to promote 
Top-Level Research” has been receiving continuous funding since 2007 
within the framework of the Excellence Initiative by the German Federal 
and State Governments.


The Faculty of Sciences, Department of Biology, seeks to fill a

W 3-Full Professorship of Biophysics

Applicants should work and be internationally recognized in the field of 
Biophysics, preferentially in structure determination of proteins. The 
applicant should be able to participate in Research Consortia (e.g. 
Collaborative Research Center (SFB969) on “Chemical and Biological 
Principles of Cellular Proteostasis” and the Graduate School GSC 218 
„Konstanz Research School Chemical Biology”). The incumbent professor is 
expected to teach Biophysics at the bachelor’s and master’s level.


Selected candidates will be invited to a scientific colloquium to be 
held in Konstanz in the winter term 2013/2014.


The University of Konstanz is an equal opportunity employer and tries to 
increase the number of women in research and teaching.


The University of Konstanz encourages disabled people to apply. They 
will be given preference if appropriately qualified.


The University of Konstanz has been certified as a family-friendly 
institution by the Hertie Foundation and is committed to further the 
compatibility of work and family life.


The University of Konstanz offers a „Dual Career Program“. Information 
can be obtained from: http://www.uni-konstanz.de/dcc .


Applications comprising a curriculum vitae, publication list, a list of 
grants and awards, details of teaching experience, as well as statements 
of current research topics, future research directions and interests 
(see pdf-link below on our website) should be sent electronically until 
15 September 2013 under the reference number 2013/136 formatted into one 
pdf-file to: prof-2013-...@uni-konstanz.de .


Further information is available on our website: 
http://www.uni-konstanz.de/stellen or by contacting Mr. Hanns Fahlbusch 
by e-mail: hanns.fahlbu...@uni-konstanz.de .

=

An "application cover form (PDF)" can be downloaded from 
http://www.uni-konstanz.de/stellenangebote/?cont=stellausw&seite=2013/136&id=3 
.

--
Kay Diederichshttp://strucbio.biologie.uni-konstanz.de
email: kay.diederi...@uni-konstanz.deTel +49 7531 88 4049 Fax 3183
Fachbereich Biologie, Universität Konstanz, Box M647, D-78457 Konstanz


[ccp4bb] VACANCY - SENIOR RESEARCHER IN GENE EXPRESSION FOR STRUCTURAL GLYCOBIOLOGY

2013-04-25 Thread Kevin Cowtan
VACANCY - SENIOR RESEARCHER IN GENE EXPRESSION FOR STRUCTURAL GLYCOBIOLOGY,
University of York, UK

Applications are invited for a Senior Researcher to play a major role in
establishing mammalian gene expression for 3-D structural and chemical
mechanistic studies in the area of eukaryotic glycobiology in health and
disease.  The project is funded by the ERC and will be supervised by
Professor Gideon Davies, FRS, in the York Structural Biology Laboratory
(YSBL).

The post holder will be responsible for the preparation of gene constructs
for the expression of mammalian carbohydrate-active enzyme genes,
expression of these genes in mammalian and insect cell lines and the
production and characterization of recombinant proteins for structural
studies.

Applicants are expected to have a PhD or equivalent qualification in
biochemistry or molecular biology and demonstrable skill, knowledge and
experience in the over-expression of genes in mammalian and/or fungal
systems.  The post will also involve extensive protein production,
purification and characterization and experience in these areas is also
required.

Salary will be within the range of £36,298 - £44,607 per year, on Grade 7
of the University salary scale.  The post is available from June 2013 for a
period of up to 59 months.

FULL DETAILS AND ONLINE APPLICATION AT -
https://jobs.york.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=3885&p_web_page_id=164510

-- 
EMAIL DISCLAIMER: http://www.york.ac.uk/docs/disclaimer/email.htm


[ccp4bb] Vacancy at PDBe for an enthusiastic junior annotator

2012-12-19 Thread Gerard DVD Kleywegt

Hi all,

The Protein Data Bank in Europe (PDBe; pdbe.org) is looking to recruit a 
junior structural biologist to join the PDBe curation team at the EBI near 
Cambridge, UK. Applicants should be computer-literate and possess a recent PhD 
in some area of structural biology or structural chemistry as well as a broad 
knowledge in molecular biology or biochemistry. An in-depth knowledge of 
protein structure (including structure determination, analysis and validation) 
is essential. A few years of post-doctoral research experience in structural 
biology, as well as hands-on experience in the determination of protein 
structure is desirable. Given the extensive interactions with colleagues in 
the PDBe team as well as with international collaborators, depositors and 
users, excellent written and oral communication skills, fluency in English, 
ability to work in a team and attention to detail are required.


More details and a link to the electronic application procedure can be found 
here:


http://ig14.i-grasp.com/fe/tpl_embl01.asp?s=bkMjPUrEcTFkHhTcz&jobid=49714,9371342323

Feel free to pass this on to suitable candidates!

--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy at PDBe for an enthusiastic junior annotator

2012-10-09 Thread Gerard DVD Kleywegt

Hi all,

The Protein Data Bank in Europe (PDBe; pdbe.org) is looking to recruit an 
expert structural biologist to join the PDBe curation team at the EBI near 
Cambridge, UK. Applicants should be computer-literate and possess a recent PhD 
in some area of structural biology or structural chemistry as well as a broad 
knowledge in molecular biology or biochemistry. An in-depth knowledge of 
protein structure (including structure determination, analysis and validation) 
is essential. A few years of post-doctoral research experience in structural 
biology, as well as hands-on experience in the determination of protein 
structure is highly desirable.


The ideal candidate will be familiar with Linux/Unix operating systems and 
molecular graphics software. Basic programming skills, e.g. with Perl, Python 
or Java, would be an advantage. Given the extensive interactions with 
colleagues in the PDBe team as well as with international collaborators, 
depositors and users, excellent written and oral communication skills, fluency 
in English, ability to work in a team and attention to detail are required.


More details and a link to the electronic application procedure can be found 
here:


http://ig14.i-grasp.com/fe/tpl_embl01.asp?s=bkMjPUrEcTFkHhTcz&jobid=49714,9371342323

Feel free to pass this on to suitable candidates!

--Gerard

PS: Some hints for prospective applicants: it doesn't hurt to add a nice cover 
letter in which you explain why you would love to be a PDB annotator and why 
PDBe strikes you as a brilliant place to work. Also, if you should get invited 
for an interview and we ask you what the main colour of our website is, please 
don't answer "blue"...


---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] Vacancy for Scientific Sales Person (100% f/m) at DECTRIS Ltd., Switzerland

2012-09-24 Thread Schulze-Briese Clemens
In order to match the rapid growth of our company and to strengthen our sales 
team
we are looking for a talented and ambitious

Scientific Sales Person (f/m, 100 %)

Tasks
•   Customer acquisition and product presentations
•   Product responsible for high performance detector series
•   Applications scientist in Powder Diffraction and related techniques
•   Technical and scientific consulting
•   Representation of the company at conferences and fairs
•   Performance and analysis of marketing relevant experiments

Requirements
•   University degree in natural sciences or engineering
•   Experienced in Powder Diffraction or X-ray crystallography
•   Sales experience or training in economics of advantage
•   Strong customer service ethic and service oriented
•   Excellent communication skills, with an enduring and team-oriented 
character
•   Highly flexible and willing to travel
•   Proficient in German and English
   
Offer
•   Unique opportunity to assume sales responsibility for top-notch X-ray 
detectors
and to identify with the product and a dynamic company 
•   Interesting work environment in a motivated team
•   The developing potential of young company that cares for its employees

Interested? We are looking forward to your qualified application. Please send 
your complete
application documents including potential references, salary expectation and 
begin date,
preferably by e-mail, to j...@dectris.com, reference no 1207.

---
Dr. Clemens Schulze-Briese   

Dectris Ltd.
Neuenhoferstr. 107
5400 Baden
Switzerland

www.dectris.com


[ccp4bb] Vacancy for Software Engineer: BioSAXS and MX automation

2012-07-26 Thread Alun Ashton
Dear All, 

Please see below details of a Software Engineer post available within the 
scientific software team at Diamond. 
It's not particularly obvious from the advertisement that the role will be to 
work with existing staff and collaborators to enhance and extend our existing 
fully automatic MX data reduction and structure solution pipelines as well as 
to help develop the equivalent for BioSAXS.

For full details please go to the web pages at:
http://www.diamond.ac.uk/Home/Jobs/Current/DIA0752_CG.html

Job Title: Software Engineer  
Job Reference: DIA0752/CG  
Post Type: Full Time- Fixed Term- 3 years 
Division: Science 
Salary information: Circa £33k 
Application deadline: 23/08/2012 
Date of interviews: TBC  


Informal enquaries can be made directly to me. 
Alun
___
Alun Ashton, alun.ash...@diamond.ac.uk Tel: +44 1235 778404
Scientific Software Team Leader,  http://www.diamond.ac.uk/
Diamond Light Source, Chilton, Didcot, Oxon, OX11 0DE, U.K.





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are not the intended addressee or an authorised recipient of the addressee 
please notify us of receipt by returning the e-mail and do not use, copy, 
retain, distribute or disclose the information in or attached to the e-mail.

Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 

Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments 
are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.

Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

 









[ccp4bb] vacancy for Java Web Application Developer at Diamond

2012-06-12 Thread Martin Walsh
Dear all, this new vacancy at Diamond may be of interest for some readers of 
this BB which is focused on further development of ISPyB at Diamond. Full 
details of the post can be found here:

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0737_TH.html

Informal inquiries can be made to myself (martin.wa...@diamond.ac.uk ) or Alun 
Ashton (alun.ash...@diamond.ac.uk)

Thanks
Martin




[ccp4bb] Vacancy for a Data Analysis Scientist: Diffraction and crystallography

2012-02-21 Thread Alun Ashton
Dear All, 

Please see below details of a data analysis scientist post available within the 
scientific software team at Diamond. For full details please go to the web 
pages at:

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0686-TH.html

Job Title: Data Analysis Scientist  
Job Reference: DIA0686/CG  
Post Type: Full time, permanent 
Division: Science 
Salary information: Circa £34k - a higher salary may be available for an 
exceptionally experienced and qualified candidate. 
Application deadline: 25/03/2012 

Regards,
Alun Ashton
___
Alun Ashton, alun.ash...@diamond.ac.uk Tel: +44 1235 778404
Scientific Software Team Leader,  http://www.diamond.ac.uk/
Diamond Light Source, Chilton, Didcot, Oxon, OX11 0DE, U.K.


[ccp4bb] Vacancy - Senior Scientific Programmer for BioStruct-X project

2012-02-03 Thread Gwyndaf Evans
Dear All,

Can I draw your attention to a job vacancy for a Senior Scientific programmer 
to work at Diamond on the development of data integration software for 
synchrotron and FEL diffraction data within the BioStruct-X project ( 
http://www.biostruct-x.eu ).

Details of the 4 year post can be found at

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0676-TH.html

Please feel free to contact me ( 
gwyndaf.ev...@diamond.ac.uk ) for more 
information about the opening.

Thanks
Gwyndaf

Dr Gwyndaf Evans
Principal Beamline Scientist for I24 Microfocus MX
Macromolecular Crystallography Village Coordinator
Diamond Light Source
Harwell Science and Innovation Campus
Didcot OX11 0DE
United Kingdom

Tel: +44-1235-778164Fax: +44-1235-778448   Email: 
gwyndaf.ev...@diamond.ac.uk



[ccp4bb] Vacancy for Scientific Database Curator (Structural Biology) at the EBI

2011-11-08 Thread Gerard DVD Kleywegt

Hi all,

The UniProt (uniprot.org) team at the EBI (www.ebi.ac.uk) currently has a 
vacancy for a structural biology curator. From the job description:


"The curator will be mainly involved with the collection, organisation and 
dissemination of data on biological macromolecular structures. (S)he will work 
closely with other team members, with UniProt Consortium partners at the Swiss 
Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR) 
and with other EBI groups, in particular with the Protein Data Bank Europe 
(PDBe)."


For more info: 
http://ig14.i-grasp.com/fe/tpl_embl01.asp?jobid=46586,3252654934&key=43184599


Note: this position is not in the PDBe team, but the post holder will work 
closely with PDBe staff on maintaining the SIFTS resource (pdbe.org/sifts) 
which contains mappings between PDB and UniProt entries as well as several 
other major resources and which is used by many bioinformatics centres and 
resources worldwide (including Pfam, SCOP, RCSB, PDBsum and DAS service 
providers).


--Gerard

---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] vacancy for a research scientist at the ILL

2011-11-07 Thread Schober Anita

  
  

Anita Schober
Institut LAUE-LANGEVIN
Service Ressources Humaines
BP 156 - 38042 GRENOBLE Cedex 9
Tél.: + 33 (0)4 76 20 72 36
Fax : + 33 (0)4 76 20 77 99
E-mail : schob...@ill.fr 
Hello,
please find below the advertisement of a vacancy for a research
scientist at the ILL.

Human Resources Service
  Institut Laue Langevin




  

  
INSTITUT MAX VON LAUE PAUL LANGEVIN
  
  
DA/SRH/GRI-07/11/2011
ILL réf. 11/24
  


  

www.ill.fr
  
  
 
VACANCY 
 
  


  
The Institut
Laue-Langevin (ILL), situated in Grenoble, France, is
Europe's leading research facility for fundamental
research using neutrons. The ILL operates the brightest
neutron source in the world, reliably delivering intense
neutron beams to 40 unique scientific instruments. The
Institute welcomes more than 2000 visiting scientists
per year to carry out world-class research in
solid-state physics, crystallography, soft matter,
biology, chemistry and fundamental physics. Funded
primarily by its three founder members: France, Germany
and the United Kingdom, the ILL has also signed
scientific collaboration agreements with 12 other
countries. The Science Division currently has a vacancy
:
RESEARCH SCIENTIST - m/f -
(small angle neutron scattering) 

Small



angle neutron scattering (SANS) has become a major
component of structural biology at the ILL to study
interactions and low resolution structures in large
biological macromolecular complexes. Furthermore the PSB
(Partnership for Structural Biology) provides
additional outstanding facilities for structural biology, including a Deuteration
  Laboratory for isotope labeling of biological
  molecules, and a wide variety of complementary
  biophysical methods. With the presence of the European
  Molecular Biology Laboratory, the Institute of
  Structural Biology and the European Synchrotron
  Radiation Facility, the campus provides an exciting
  research environment for biology.
Duties:
The ILL is inviting applications for a scientist to take
charge of the biological aspects of the SANS instrument
D22 in the Large Scale Structures group. Duties would
include: instrument maintenance and development, running
data collection and analysis software, local contact for
biology experiments both on D22 and on the other SANS
instruments of the group, and to coordinate the system
of beamtime block allocation to experimenters. The
candidate will also be encouraged to develop strong
collaborations for her/his own scientific work. 
Qualifications



  and experience:
Ph.D. in physical or life sciences. We are particularly
interested in highly motivated candidates with an active
research interest in biology, experience in neutron or
X-ray small angle scattering.
The post represents an excellent opportunity for a young
postdoctoral scientist to develop expertise, broaden
their experience and interact with leading scientists
from around the world. Applications from more
experienced scientists who are able to obtain a
secondment period from their home institute will also be
considered. 
Language skills:
As an international research centre, we are particularly
keen to ensure that we also attract applicants from
outside France. You must have a sound knowledge of
English and be willing to learn French (a language
course will be paid for by the ILL). Knowledge of German
would be an advantage.
Notes:
Fixed-term contract of 5 years.
Further information can be obtained by contacting the
head of the Large Scale Structures Group: Dr. R Cubitt, Tel.
+33(0)4.76.20.72.15, e-mail: cub...@ill.fr (please
do not send your application to this address) or via http://www.ill.fr/lss.
Benefits:  
 

[ccp4bb] Vacancy at PDBe for an enthusiastic junior annotator

2011-09-20 Thread Gerard DVD Kleywegt

Hi all,

The Protein Data Bank in Europe (PDBe; pdbe.org) is looking to recruit an 
expert structural biologist to join the PDBe curation team at the EBI near 
Cambridge, UK. Applicants should be computer-literate and possess a recent PhD 
in some area of structural biology or structural chemistry as well as a broad 
knowledge in molecular biology or biochemistry. An in-depth knowledge of 
protein structure (including structure determination, analysis and validation) 
is essential. A few years of post-doctoral research experience in structural 
biology, as well as hands-on experience in the determination of protein 
structure is highly desirable.


The ideal candidate will be familiar with Linux/Unix operating systems and 
molecular graphics software. Basic programming skills, e.g. with Perl, Python 
or Java, would be an advantage. Given the extensive interactions with 
colleagues in the PDBe team as well as with international collaborators, 
depositors and users, excellent written and oral communication skills, fluency 
in English, ability to work in a team and attention to detail are required.


More details and a link to the electronic application procedure can be found 
here:


http://ig14.i-grasp.com/fe/tpl_embl01.asp?s=MbkMjPUrEcTFkHhTcz&jobid=46332,8998483234

Feel free to pass this on to suitable candidates!

--Gerard

PS: Some hints for prospective applicants: it doesn't hurt to add a nice cover 
letter in which you explain why you would love to be a PDB annotator and why 
PDBe strikes you as a brilliant place to work. Also, if you should get invited 
for an interview and we ask you what the main colour of our website is, please 
don't answer "blue"...


---
Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk . pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk


[ccp4bb] vacancy for a research scientist at the ILL

2011-06-10 Thread Schober Anita


  
  
Hello,
please find below the advertisement of a vacancy for a research
scientist at the ILL.

Anita Schober
  Human Resources Service
  Institut Laue Langevin




  

  
INSTITUT MAX VON LAUE PAUL LANGEVIN
  
  
DA/SRH/GRI-01/06/2011
ILL réf. 11/15
  


  

www.ill.fr
  
  
 
VACANCY 
 
  


  
The Institut
Laue-Langevin (ILL), situated in Grenoble, France, is
Europe's leading research facility for fundamental
research using neutrons. The ILL operates the brightest
neutron source in the world, reliably delivering intense
neutron beams to 40 unique scientific instruments. The
Institute welcomes more than 2000 visiting scientists
per year to carry out world-class research in
solid-state physics, crystallography, soft matter,
biology, chemistry and fundamental physics. Funded
primarily by its three founder members: France, Germany
and the United Kingdom, the ILL has also signed
scientific collaboration agreements with 12 other
countries. The Science Division currently has a vacancy
:
RESEARCH SCIENTIST - m/f -
(small angle neutron scattering) 

Small



angle neutron scattering (SANS) has become a major
component of structural biology at the ILL to study
interactions and low resolution structures in large
biological macromolecular complexes. Furthermore the PSB
(Partnership for Structural Biology) provides
additional outstanding facilities for structural biology, including a Deuteration
  Laboratory for isotope labeling of biological
  molecules, and a wide variety of complementary
  biophysical methods. With the presence of the European
  Molecular Biology Laboratory, the Institute of
  Structural Biology and the European Synchrotron
  Radiation Facility, the campus provides an exciting
  research environment for biology.
Duties:
The ILL is inviting applications for a scientist to take
charge of the biological aspects of the SANS instrument
D22 in the Large Scale Structures group. Duties would
include: instrument maintenance and development, running
data collection and analysis software, local contact for
biology experiments both on D22 and on the other SANS
instruments of the group, and to coordinate the system
of beamtime block allocation to experimenters. The
candidate will also be encouraged to develop strong
collaborations for her/his own scientific work. 
Qualifications



  and experience:
Ph.D. in physical or life sciences. We are particularly
interested in highly motivated candidates with an active
research interest in biology, experience in neutron or
X-ray small angle scattering.
The post represents an excellent opportunity for a young
postdoctoral scientist to develop expertise, broaden
their experience and interact with leading scientists
from around the world. Applications from more
experienced scientists who are able to obtain a
secondment period from their home institute will also be
considered. 
Language skills:
As an international research centre, we are particularly
keen to ensure that we also attract applicants from
outside France. You must have a sound knowledge of
English and be willing to learn French (a language
course will be paid for by the ILL). Knowledge of German
would be an advantage.
Notes:
Fixed-term contract of 5 years.
Further information can be obtained by contacting the
head of the Large Scale Structures Group: Dr. R Cubitt, Tel.
+33(0)4.76.20.72.15, e-mail: cub...@ill.fr or via http://www.ill.fr/lss.
Benefits:  
  Generous company benefits (adaptation and
expatriation allowance), relocation assistance and
language courses may be offered.
How to apply:
Please submit your application on li

[ccp4bb] Vacancy Notice for a Scientific Project Manager, EMBL Hamburg Unit

2011-05-16 Thread Margret Fischer

Dear all,
I would like to draw your attention to the following Vacancy Notice at 
the EMBL, Hamburg Unit:



Scientific Project Manager,  Reference number:  HH_00012

EMBL is seeking an EU Project Manager for the European research 
infrastructure project, "Transnational access and enhancement of 
integrated Biological Structure determination at synchrotron X-ray 
facilities (BioStruct-X)".


The project will be coordinated by EMBL Hamburg and will include a total 
of 19 partners from 10 European countries and Israel. It will provide 
supported access to state-of-the-art structural biology facilities in 
protein crystallography, small angle X-ray scattering, X-ray imaging and 
protein production. It will be complemented by a series of focused joint 
research and networking activities in relevant areas. The project is 
anticipated to start in the autumn 2011 and will run for four years.


The successful candidate will work closely with the scientific 
coordinator Matthias Wilmanns, the executive committee, all members of 
the consortium, and the funding organization (European Commission). The 
first tasks will be the establishment of appropriate management, data 
base, dissemination and networking structures of the project.


Further information can be obtained under the following link:
http://www.embl-hamburg.de/aboutus/jobs/searchjobs/index.php?newlang=1&newms=sr&searchregion=668


regards
Margret Fischer


[ccp4bb] Vacancy for crystallographer at Boston Univ School of Medicine

2009-08-20 Thread Hwai-Chen Guo

Dear All,

 I wish to bring your attention to a crystallographer postdoctoral opening 
at Boston University School of Medicine. Please see the job description below. 
Thanks,

HC Guo

Postdoctoral Fellow Position Open
Boston University School of Medicine
Department: Physiology and Biophysics
Location: Boston, Mass
URL: biophysics.bumc.bu.edu/faculty/guo/index.html
Start Date: immediately
Duration: 1-3 years
Description: A postdoctoral position is open for highly motivated individuals 
to work on biochemical and crystallographic studies of enzymes involved in 
post-translational processings and immunity. Some crystals are already 
available. The work may involve any aspect of protein purification, 
mutagenesis, crystal growth, data collection, model building and refinement. 
Suitable candidates will also have the chance to participate in the biochemical 
characterization of the proteins. A background in protein 
expression/biochemistry and/or x-ray structure determination is prerequisite. 
Experienced macromolecular crystallographers are preferred, but highly 
motivated recent graduates with a strong background in protein biochemistry and 
interested in learning crystallography are also encouraged to apply. The 
laboratory is fully equipped for biochemical experiments, and with 
state-of-the-art crystallographic facilities. In addition, the National 
Synchrotron Light Source at the Brookhaven National Laboratory is only 5-hour 
driving/ferry away. Available immediately, applications will be accepted till 
positions filled.
Other details: Equal Opportunity Employer 
Please submit: Cover letter with curriculum vita and the names and addresses 
(including e-mail addresses) of three referees
Person to contact: Dr. Hwai-Chen Guo
Surface mail address: 700 Albany Street, Boston, MA 02118
Email address: hc...@bu.edu
Phone number: 617-638-4023



[ccp4bb] Vacancy: Scientific Database Curator- PDBe

2009-08-20 Thread Jawahar Swaminathan

Dear All,
I wish to draw your attention to a recent post opening at the Protein 
Databank in Europe (http://www.ebi.ac.uk/pdbe/) for a Scientific 
Database Curator. Details of the job and application procedure below:

Thanks - Jawahar Swaminathan
PDBe, European Bioinformatics Institute,
Cambridge CB10 1SD UK
---

SCIENTIFIC DATABASE CURATOR***

Grade: 4, 5 or 6, depending on qualifications and experience
Duty Station: EMBL-EBI Hinxton, near Cambridge, UK
Commencing date: As soon as possible
Job description:
The high quality curation of PDB entries is essential in establishing 
the PDBe database as a world-leading source of protein-structure 
information. To maintain and extend this position, the PDBe team is 
looking for an expert biologist for a demanding role in database 
curation. The work will involve annotating preliminary PDB submissions 
and extracting biological information relevant to a given entry. In 
addition, curators will draw on their own areas of expertise in 
contributing to the development of methods and procedures. 

Qualifications and experience: 
The postholder should hold a PhD in some area of structural biology or 
chemistry as well as have a broad knowledge in molecular biology. An 
indepth knowledge of biochemistry and/or protein structure analysis 
would be highly beneficial. The successful candidate will be computer 
literate and have proven experience of Linux/Unix, Emacs and molecular 
graphics software and scripting experience would be advantageous. 
Excellent communication and interpersonal skills are essential as is the 
ability to work as part of a team and pay particular attention to detail.  

Contract: An initial contract of 3 years will be offered to the 
successful candidate. This can be renewed, depending on circumstances at 
the time of the review.


Closing date:  13 September 2009
EMBL is an inclusive, equal opportunity employer offering attractive 
conditions and benefits appropriate to an international research 
organisation.


Please note that EMBL does not return CVs or attached documents to 
applicants.


**To apply, please send a CV (including names and addresses of referees) 
and covering letter, by email, quoting ref. no. W/09/071/EBI in the 
subject line, to: applicati...@ebi.ac.uk
General enquiries may be sent to applicati...@ebi.ac.uk or to the 
following address:

EMBL-EBI, Personnel, Wellcome Trust Genome Campus, Hinxton, CB10 1SD.
**--


[ccp4bb] Vacancy for crystallographer at Heptares

2009-08-18 Thread Andrew Leslie
This is posted on behalf of Dr. Fiona Marshall at Heptares. The 
Heptares web site for applications is:

 http://home.btconnect.com/heptares/vacancies.html

Please respond using the web site or the Email address below, not to me.

Andrew Leslie

Structural Biologist/Crystallographer

Heptares is a new drug discovery company located in Hertfordshire UK, 
working on G protein coupled receptors across a range of therapeutic 
areas.  We are using a unique structure based approach, which 
originated from work at the MRC Laboratory of Molecular Biology in 
Cambridge, to characterise this important family of receptors and 
develop novel innovative therapeutics for the treatment of disease.


We have recently established a state of the art laboratory for membrane 
protein crystallography. We are now seeking an enthusiastic and 
motivated scientist with experience in protein crystallisation and 
structure determination to assist Heptares in obtaining novel GPCRs 
structures and ligand co-structures for drug discovery.  This is an 
exceptional opportunity to participate in cutting edge science whilst 
helping to grow an industry-leading drug discovery company.


The successful candidate will work closely with the protein engineering 
and expression team responsible for the generation of pure stabilised 
GPCRs.  In addition the role will include close collaboration with 
medicinal and computational chemists involved in structure based drug 
design


It is expected that some candidates will have broad experience of 
protein purification through to structure whilst others may wish to 
focus on crystallography.


The role will include some or all of the following depending on the 
candidate:
•	Develop and optimise protocols for receptor purification with a view 
to crystallisation

•   Develop protocols for crystallisation of novel stabilised GPCRs
•	Set up crystallisation screens and optimise conditions for GPCR 
crystals

•   Data collection at synchrotrons (Diamond and ESRF)
•   Structure determination of protein ligand complexes

Qualifications
The successful candidate should have:
•	A PhD or equivalent in biophysics, structural biology or related 
discipline
•	At least 5 years experience within a research environment either in 
academia or industry.

•   Experience in protein purification and crystallisation
•   Extensive skills in X-ray macromolecular crystallography
•   Analytical thinking and critical problem solving skills.
•	Experience of working with membrane proteins would be an advantage as 
would experience of working in a drug discovery environment where 
structural studies are used to drive medicinal chemistry

•   Excellent time management skills and an ability to work independently.
•   An interest in G protein coupled receptors and drug discovery.
Further information can be found on our website (www.heptares.com).
Applications should be sent to i...@heptares.com.


[ccp4bb] Vacancy posting: PhD student position in structural biology / protein crystallography

2008-06-16 Thread Sergei Strelkov




A PhD student position in protein
crystallography / structural
biology is available in the
Laboratory for
Biocrystallography, Department of Pharmaceutical Sciences, University of Leuven, Belgium
(http://pharm.kuleuven.be/anafar/).


The PhD student will participate in one or more
high-impact
medically-oriented structural biology 
projects carried out in
intramural and
international collaboration. The activities of the successful
 candidate
will include recombinant
protein isolation, crystallization, X-ray crystallographic
 and
small-angle
solution scattering studies as well as modelling.


The applicant should have a MSc or a
BSc diploma in
biochemistry, biophysics, bioinformatics
 or a related field. A record
of
research experience is a scientific laboratory is a must. Strong
interest
 in computational methods is a plus. The working language will be
English.


Our laboratory is hosted in a brand-new building
and is
fully equipped with an X-ray diffractometer 
(Rigaku/Mar),
crystallization
facilities, wet labs and a computer cluster. Leuven is a university
town
 located 20 km east of Brussels.
The University of Leuven is ranked among the top centres for

biomedical
research in Belgium.
Rich history, remarkable architecture and proximity of Brussels,

Paris and London
make
Leuven an outstanding location. 

The search for suitable candidates is open
immediately and
will continue until the position is filled. 
The target starting date is
September
1st, 2008, but can be negotiated.  Please
address any further 
questions and/or your application, including a
detailed CV,
publication list and a list of referees, 
to Prof. Sergei Strelkov via
e-mail.


Disclaimer: http://www.kuleuven.be/cwis/email_disclaimer.htm for more information.