Re: Some More Virbagen Omega Info
A: Studies have demonstrated a stability of the molecule up to 3 weeks minimum at +4C. Nevertheless, taking into consideration the fact that there is no preservative in the formulation of the product, the risk of contamination with fungus or bacteria exists. Nevertheless, if injections are performed in asepsis conditions (sterile needles...), the risk of contamination will be minimum. Kyle, This is fantastic news! Thanks so much for finding this out for us. I was terrified of using "left-over" feline interferon, now it appears it's safe as long as adequate sterilization methods are used with the vials. I'm so pleased, this means we can stretch the premeasured vials! I haven't had time to explore the link you provided, but you can be sure I will. I'm also going to forward it to my vet's office. I'll also send it to my biochemist pal, Kate, and ask her to translate the last paragraph! Thanks Kyle, you're a gem! Nina Melbeach wrote: Found some more info on VO ya'll might be interested in. From Virbac's FAQ: http://www.virbagenomega.com/uk/faqcat Q: After reconstitution of Virbagen Omega, can the vial be stored overnight and used on an animal the next day? A: Studies have demonstrated a stability of the molecule up to 3 weeks minimum at +4C. Nevertheless, taking into consideration the fact that there is no preservative in the formulation of the product, the risk of contamination with fungus or bacteria exists. Nevertheless, if injections are performed in asepsis conditions (sterile needles...), the risk of contamination will be minimum. Q: Can Virbagen Omega be frozen after reconstitution? A: Feline omega interferon is a glycoprotein which is very stable in general. After resuspension, stability studies showed that the solution was stable for at least 3 weeks at +4C. According to knowledge on the molecule, it does not seem there is any risk linked to freezing the solution. Nevertheless, precise data concerning this type of storage are not available to date. In any case, several cycles of freezing-thawing are not recommended. The official pdf documents filed with the European Medicines Agency are here: http://www.emea.eu.int/vetdocs/vets/Epar/virbagenomega/virbagenomega.htm The "Scientific Discussion" is real detailed and informative. The "Product Information" looks like the official Product Insert info. Australian FDA info: http://www.apvma.gov.au/gazette/gazette0111p14.shtml A study where only 1 round of 5 injections was applied for FeLV, instead of the recommended 3 rounds: http://vetinterferon.nexenservices.com/aff_abstract.php?id=55lang=eng I was interested in possible interference with Immunoregulin and/or continuing with Immunoregulin after VO therapy is complete. The Scientific Discussion has a small blurb that says "Due to the indications for use, concomitant use of immunological products is not recommended." Yet interestingly, the Product Information is silent on this. So I emailed Virbac and they said: "Unfortunately, as far as I am aware, ImmunoRegulin is not available in Europe and we do not have any data on the use of it either concurrently with Virbagen Omega or before/after VO treatment. There are products available in Europe (Baypamun HK and Acemannan) that are similar in concept to ImmunoRegulin. My understanding of these products is that they work by inducing the production of endogenous cytokines (including Interferons) but that placebo controlled studies have failed to demonstrate a significant benefit of treatment with these products. On this basis I can see little benefit in continuing with ImmunoRegulin treatment as Virbagen Omega effectively bypasses the need to produce endogenous type 1 interferons and will stimulate an immunological cascade itself." Anyone know what that means? -Kyle
Re: New To List - Welcome Kris
Hi Kris, I'm sorry it took so long to write, but I've been pretty overwhelmed with illness and injury right now. I have been following the list as best I can and I just wanted you to know how sorry I am you had to find us. This disease is horrid, and every cat seems to be effected in different ways and degrees. One thing I have discovered is, there is always cause for hope. It's constantly testing my mettle, and I have found out I'm stronger and more courageous than I would have previously imagined. As far as cross-mixing goes... I have never found a vet, or anything in my research that suggests mixing is a good idea. And why would they? Of course there's less of a chance of infection if they're separated, that's common sense. That being said, it was never an option for me to isolate any of my animals. If my husband came down with smallpox, I wouldn't make him go live in the garage! It may have been an easier decision for me. When I found out mine were positive, it was long after they had become part of the family. They had been co-mingling for so long that it didn't make sense for me to separate them at that point. Besides they wouldn't have understood, everyone has access to everywhere and everyone else, they would have been so unhappy and confused if I had shut them away somewhere. I know it's a risk, but it's a risk I feel compelled to take. Based on my own experience and that of others on this list, I have since found out that the risk is much slimmer than I had been led to believe. My FeLV+ are now 17 months old and I've had them since they were 2 1/2 weeks. None of my other cats have become positive. I would strongly recommend vaccinating your negatives, (be careful, in my haste to protect a semi-feral the same age as my FeLV kittens, I allowed my vet to accidently over-vaccinate her and she has IBD now). No one can make this decision for you, you are the one who must be willing to live with the consequences, but quality of life is of the utmost importance to me, and from your posts your negative cats seem very unhappy, (so do you for that matter!). I just read one of Sally's post about Purrki testing positive as a kitten and then recently testing negative. I just wanted to mention that, Tim, one of the kittens from my FeLV litter, has tested negative also. That's what I mean by there always being room for hope. Everything I read, and I've read a lot, said that a kitten contracting FeLV inutro has a very slim prognosis for clearing the virus, but here's my Tim, handsome and strong with no signs of illness and testing negative! It's true that it could be sequestered in his bone marrow, but I continue to treat him as if he's positive, (he gets all the supplements and close scrutiny as his sisters) and still allow myself the joy in knowing that he's tested negative. There is also the possibility of your cats being carriers that test positive, without ever showing the ill-effects associated with the disease. It's all such a crap-shoot, but isn't life in general that way? That's another thing this disease has taught me, I don't have nearly the control over my environment that I once thought I did. It's a fine line that I continue to battle. I can't advise you about Retrovir, I'd never heard of it before you mentioned it. I do know that, in my case, feline interferon, Doxycycline and Sally's Transfer Factors has helped my babies recover when I thought all was lost. The most important things are to keep the household stress-free, provide good nutrition and supplements and watch them like a hawk to jump on any sign of illness before it can take hold. If/when you do start mixing your household again, watch your negatives for illness as well, as Sally has stated they are probably bigger threats to your FeLV, than the other way around! I'm very pleased to hear Thor is doing better. You, Luna, Thor and the rest of your family are in my thoughts and prayers. You're never alone. You've found a warm, knowledgeable and supportive group of people on this list. I don't know what I would do without them. Nina Kris Kulak wrote: Wow Sally, You are extremely informative and easier to comprehend than some sites I've been too. I greatly appreciate your response. I've had the older kitten tested IFA because he was so sick at the time, I wanted a complete check-up, never thinking this would happen since all of my cats are indoor creatures. The other 4 had the ELISA because I wanted an idea right away. I was so devastated at the time, I wanted to know ASAP. I do have the 3 older ones isolated to the basement and the two little guys upstairs with me where we can keep a better eye on them. I hope this is only temporary because it is extremely hard on the cats and the rest of the family. We have to sneak in and out of the door which is not easy with 5 cats trying to sneak with you. They meow or howl or scratch back and forth at the door constantly. The littlest guy (Luna) is about 4 months old. He acts
Re: Kelp or Spirulina
They are both high in iron. I was told to be careful by my homepathic vet with them due to the high iron when my cat was anemic. But I did use the Spirulina there is a drink with it at a the health stores and my cat seemed to like the taste. It's high in B vitamins. You can do a search on the net and should be able to order on line if you can't find it in the stores. GNC carry kelp I think maybe the other. Carla Date sent: Tue, 08 Mar 2005 17:22:54 -0800 From: catstevens [EMAIL PROTECTED] To: felvtalk@felineleukemia.org Copies to: Subject:Liver shake Send reply to: felvtalk@felineleukemia.org Kelp or spirulina
Re: Please Help! Anakin is very sick
Epogen and injectable steroids may help but that takes time to kick in and you would probably have to give him a transfusion or two to buy enough time to see if that would help. EPOGEN may ALSO help if the bone marrow is no longer producing enough RBC's as I have said time and time again, Jean Luc and cat with lymphoma, and crf got EPOGEN for over two years on and off as needed and his bone marrow went down from 13 to 11, they stared the epogen when it was 13, and it WAS non regenerative anemia. He WAS NOT FeLV positive so I don't know what that status would throw in the mix, and since nobody seems willing to try it before the cat is so sick it is probably beyond help I guess we'll never know. The only cat I know of that tried the epogen that was positive had a hemocrit of I believe 6 when it was started, and since epogen can take up to three weeks to really kick in I don't think it was started in time to have a chance to work. PS Jean Luc's lymphoma was diagnosed shortly after he was already getting the epogen for anemia, so it could be possible the lymphoma caused the anemia and it was the symptom that brought about checking for lymphoma. -- Belinda Happiness is being owned by cats ... Be-Mi-Kitties ... http://www.bemikitties.com Post Adoptable FeLV/FIV/FIP Cats/Kittens http://adopt.bemikitties.com FeLV Candle Light Service http://www.bemikitties.com/cls HostDesign4U.com (affordable hosting web design) http://HostDesign4U.com --- BMK Designs (non-profit web sites) http://bmk.bemikitties.com
Re: More On Epogen (Procrit)
In a later email she said in reality even though vets say the antibodies only developed in 30% of the cases. That means 70% of the cats never developed antibodies it is closer to 10% developing antibodies (and usually only after 3 or 4 months of use) and 90% never developing them according to what her vet has actually experienced. -- Belinda Happiness is being owned by cats ... Be-Mi-Kitties ... http://www.bemikitties.com Post Adoptable FeLV/FIV/FIP Cats/Kittens http://adopt.bemikitties.com FeLV Candle Light Service http://www.bemikitties.com/cls HostDesign4U.com (affordable hosting web design) http://HostDesign4U.com --- BMK Designs (non-profit web sites) http://bmk.bemikitties.com
Uh-oh-oh update -pls help!!
I took Uh-oh-oh to the vet yesterday afternoon and heres what I found out The good news was he was negative on FeLV/FIV (thank god!) on ELISA When they did in house PCV test, his HCT was 44 which was very good. But I also had them sent out the blood work for the total body function so that I can find out whats going on with him And heres a sort of bad news, and I am not sure whats going on and I need your help to understand it. His PCV (HCT) was much lower than the results from the house, which is 32, but still within the normal range of 29 to 48 But his RBC and HGB was extremely low. RBC is 1.8 (normal range 5.92 to 9.93) and HGB was 5.2 (range 9.3 to 15.9). His WBC was normal. His MCH was high 28.2 (range 11-21) and MCHC was high as well as 75 (range 30 to 38). There was a comment underneath says the sample appears hemolyzed. Hematorit by manual method. Which I was not sure what it meant. His blood parasites came as negative. Back in January, we also did PCR test of Hematot (sorry, cant spell, but its for FIA) and came back as negative what do you think going on? The fact that his RBC is now from 5.6 (in January) to 1.8 (yesterday) does this mean that his is not producing blood what does it mean?? How come his HCT is normal? (what does HCT mean? Please help me understand whats going on with Uh-oh-oh (I left a message with my vet to discuss this further, also) Hideyo Uh-oh-oh
RE: Uh-oh-oh update -pls help!!
By the way, his HCT was up from 25 (thats when he got sick in January) to 32. -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Hideyo Yamamoto Sent: Wednesday, March 09, 2005 10:20 AM To: felvtalk@felineleukemia.org Subject: Uh-oh-oh update -pls help!! I took Uh-oh-oh to the vet yesterday afternoon and heres what I found out The good news was he was negative on FeLV/FIV (thank god!) on ELISA When they did in house PCV test, his HCT was 44 which was very good. But I also had them sent out the blood work for the total body function so that I can find out whats going on with him And heres a sort of bad news, and I am not sure whats going on and I need your help to understand it. His PCV (HCT) was much lower than the results from the house, which is 32, but still within the normal range of 29 to 48 But his RBC and HGB was extremely low. RBC is 1.8 (normal range 5.92 to 9.93) and HGB was 5.2 (range 9.3 to 15.9). His WBC was normal. His MCH was high 28.2 (range 11-21) and MCHC was high as well as 75 (range 30 to 38). There was a comment underneath says the sample appears hemolyzed. Hematorit by manual method. Which I was not sure what it meant. His blood parasites came as negative. Back in January, we also did PCR test of Hematot (sorry, cant spell, but its for FIA) and came back as negative what do you think going on? The fact that his RBC is now from 5.6 (in January) to 1.8 (yesterday) does this mean that his is not producing blood what does it mean?? How come his HCT is normal? (what does HCT mean? Please help me understand whats going on with Uh-oh-oh (I left a message with my vet to discuss this further, also) Hideyo Uh-oh-oh
Re: Uh-oh-oh update -pls help!!
Hideyo, I had this page bookmarked that briefly explains the charts: http://www.dogsadversereactions.com/labtests.html. Of course this is a dog website. But the descriptions should still apply. My chart for Brissle didn't even have RBC, only HCT. I'm no expert in deciphering charts. Sorry I can't help with that.I hope there's something good in those numbers! -Kyle - Original Message - From: Hideyo Yamamoto To: felvtalk@felineleukemia.org Sent: Wednesday, March 09, 2005 12:34 PM Subject: RE: Uh-oh-oh update -pls help!! By the way, his HCT was up from 25 (thats when he got sick in January) to 32. -Original Message-From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Hideyo YamamotoSent: Wednesday, March 09, 2005 10:20 AMTo: felvtalk@felineleukemia.orgSubject: Uh-oh-oh update -pls help!! I took Uh-oh-oh to the vet yesterday afternoon and heres what I found out The good news was he was negative on FeLV/FIV (thank god!) on ELISA When they did in house PCV test, his HCT was 44 which was very good. But I also had them sent out the blood work for the total body function so that I can find out whats going on with him And heres a sort of bad news, and I am not sure whats going on and I need your help to understand it. His PCV (HCT) was much lower than the results from the house, which is 32, but still within the normal range of 29 to 48 But his RBC and HGB was extremely low. RBC is 1.8 (normal range 5.92 to 9.93) and HGB was 5.2 (range 9.3 to 15.9). His WBC was normal. His MCH was high 28.2 (range 11-21) and MCHC was high as well as 75 (range 30 to 38). There was a comment underneath says the sample appears hemolyzed. Hematorit by manual method. Which I was not sure what it meant. His blood parasites came as negative. Back in January, we also did PCR test of Hematot (sorry, cant spell, but its for FIA) and came back as negative what do you think going on? The fact that his RBC is now from 5.6 (in January) to 1.8 (yesterday) does this mean that his is not producing blood what does it mean?? How come his HCT is normal? (what does HCT mean? Please help me understand whats going on with Uh-oh-oh (I left a message with my vet to discuss this further, also) Hideyo Uh-oh-oh
Re: Liver shake
Also, if you make it without the kelp/spirulina, I would use V-8 juice instead of carrot or tomato, because it includes greens in it (the vitamins that are in kelp/spirulina) and is somewhat salty. Michelle
Re: Some More Virbagen Omega Info
I was told to give Lucy 5 mu at a time, which is a whole vial and would leave nothing over. She is almost 11 pounds. Nina, do you have some left over because Jazz or Grace weighs under 11 pounds and so gets less than 5 mu at a time? Since Lucy appears not to need surgery, I am just holding on to the VO for now. We need to move in a few months and I may use it before the move. Michelle In a message dated 3/9/05 3:40:07 AM Eastern Standard Time, [EMAIL PROTECTED] writes: A: Studies have demonstrated a stability of the molecule up to 3 weeks minimum at +4°C. Nevertheless, taking into consideration the fact that there is no preservative in the formulation of the product, the risk of contamination with fungus or bacteria exists. Nevertheless, if injections are performed in asepsis conditions (sterile needles...), the risk of contamination will be minimum.Kyle,This is fantastic news! Thanks so much for finding this out for us. I was terrified of using "left-over" feline interferon, now it appears it's safe as long as adequate sterilization methods are used with the vials. I'm so pleased, this means we can stretch the premeasured vials! I haven't had time to explore the link you provided, but you can be sure I will. I'm also going to forward it to my vet's office. I'll also send it to my biochemist pal, Kate, and ask her to translate the last paragraph!Thanks Kyle, you're a gem!Nina
Re: Additional information for those interested in Virbagen Feline Omega Inte...
Dear Kyle: Seroconversion means that the cat has cleared the virus and is no longer infected with it. That is the best possible news for a cat that was FeLV+. Sally in San Jose
Re: Kelp or Spirulina
In the shake, it's only 1 tsp kelp or spirulina for an amount of shake that should last 2 or 3 days (I make less of it at a time because I am not sure it keeps well), so I don't think that amount should overdose anyone on anything. Michelle In a message dated 3/9/05 8:42:39 AM Eastern Standard Time, [EMAIL PROTECTED] writes: They are both high in iron. I was told to be careful by my homepathic vet with them due to the high iron when my cat was anemic. But I did use the Spirulina there is a drink with it at a the health stores and my cat seemed to like the taste. It's high in B vitamins.You can do a search on the net and should be able to order on line if you can't find it in the stores. GNC carry kelp I think maybe the other.Carla
Re: Kelp or Spirulina
Michelle That should be fine I would think also. Carla From: [EMAIL PROTECTED] Date sent: Wed, 9 Mar 2005 14:31:20 EST To: felvtalk@felineleukemia.org Copies to: Subject:Re: Kelp or Spirulina Send reply to: felvtalk@felineleukemia.org In the shake, it's only 1 tsp kelp or spirulina for an amount of shake that should last 2 or 3 days (I make less of it at a time because I am not sure it keeps well), so I don't think that amount should overdose anyone on anything. Michelle In a message dated 3/9/05 8:42:39 AM Eastern Standard Time, [EMAIL PROTECTED] writes: They are both high in iron. I was told to be careful by my homepathic vet with them due to the high iron when my cat was anemic. But I did use the Spirulina there is a drink with it at a the health stores and my cat seemed to like the taste. It's high in B vitamins. You can do a search on the net and should be able to order on line if you can't find it in the stores. GNC carry kelp I think maybe the other. Carla
RE: Uh-oh-oh update -pls help!!
I am sorry I can not help, but I sending healing vibes your way CherieHideyo Yamamoto [EMAIL PROTECTED] wrote: By the way, his HCT was up from 25 (thats when he got sick in January) to 32. -Original Message-From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Hideyo YamamotoSent: Wednesday, March 09, 2005 10:20 AMTo: felvtalk@felineleukemia.orgSubject: Uh-oh-oh update -pls help!! I took Uh-oh-oh to the vet yesterday afternoon and heres what I found out The good news was he was negative on FeLV/FIV (thank god!) on ELISA When they did in house PCV test, his HCT was 44 which was very good. But I also had them sent out the blood work for the total body function so that I can find out whats going on with him And heres a sort of bad news, and I am not sure whats going on and I need your help to understand it. His PCV (HCT) was much lower than the results from the house, which is 32, but still within the normal range of 29 to 48 But his RBC and HGB was extremely low. RBC is 1.8 (normal range 5.92 to 9.93) and HGB was 5.2 (range 9.3 to 15.9). His WBC was normal. His MCH was high 28.2 (range 11-21) and MCHC was high as well as 75 (range 30 to 38). There was a comment underneath says the sample appears hemolyzed. Hematorit by manual method. Which I was not sure what it meant. His blood parasites came as negative. Back in January, we also did PCR test of Hematot (sorry, cant spell, but its for FIA) and came back as negative what do you think going on? The fact that his RBC is now from 5.6 (in January) to 1.8 (yesterday) does this mean that his is not producing blood what does it mean?? How come his HCT is normal? (what does HCT mean? Please help me understand whats going on with Uh-oh-oh (I left a message with my vet to discuss this further, also) Hideyo Uh-oh-oh
Re: Some More Virbagen Omega Info
I was splitting each vial between Jazz and Grace. The protocol I used called for one large dose (3/4 of the vial) followed in subsequent weeks by 1/4 of the vial (each day for 5 days). I would give the first large dose to whomever was sicker, the middle phase both would get the smaller amount (wasting 1/2 a vial), and then the other cat would receive the larger dose during the last phase. Does this make sense? Neither of them has ever received a full vial in one injection. Nina [EMAIL PROTECTED] wrote: I was told to give Lucy 5 mu at a time, which is a whole vial and would leave nothing over. She is almost 11 pounds. Nina, do you have some left over because Jazz or Grace weighs under 11 pounds and so gets less than 5 mu at a time? Since Lucy appears not to need surgery, I am just holding on to the VO for now. We need to move in a few months and I may use it before the move. Michelle In a message dated 3/9/05 3:40:07 AM Eastern Standard Time, [EMAIL PROTECTED] writes: A: Studies have demonstrated a stability of the molecule up to 3 weeks minimum at +4C. Nevertheless, taking into consideration the fact that there is no preservative in the formulation of the product, the risk of contamination with fungus or bacteria exists. Nevertheless, if injections are performed in asepsis conditions (sterile needles...), the risk of contamination will be minimum. Kyle, This is fantastic news! Thanks so much for finding this out for us. I was terrified of using "left-over" feline interferon, now it appears it's safe as long as adequate sterilization methods are used with the vials. I'm so pleased, this means we can stretch the premeasured vials! I haven't had time to explore the link you provided, but you can be sure I will. I'm also going to forward it to my vet's office. I'll also send it to my biochemist pal, Kate, and ask her to translate the last paragraph! Thanks Kyle, you're a gem! Nina
Re: Help with medicating/pilling/ feline interferon
As for pilling, I have a lot of luck with covering the pill in Nutrical before pilling. It tastes good to them and lubricates it, and also makes it stick to their mouth when you pill them so harder to spit out. I was also thinking of Nina's idea-- that those of us who can afford it try to keep some VO on hand so when any of us are in an emergency someone will have it and can send it (with reimbursement, of course). I had 3 boxes that were supposed to be for Simon but arrived too late. I sent one to Kyle. I have 2 more I am holding on to. I will see if my regular vet can apply for it for Lucy so I can get more, in which case I could send more to people in emergency situations. But I want to keep some on hand. I would suggest everyone who can afford it start the process and at least get the application approved, even if not ordering the medicine, so that it is only a 2 week wait instead of 2 month wait if you or someone else needs it. Michelle In a message dated 3/9/05 3:40:15 PM Eastern Standard Time, [EMAIL PROTECTED] writes: Another hint; after you get approval, have your vet send in another application. That way you have an approved app waiting for you should you decide to order more. Maybe we should all do this for each other on the list. That way those in crisis will have feline interferon when they need it most.
Re: Intercat by Toray Industries - Intercat IS Virbac's Feline Interferon.....
Virbac is the company that we have gotten our feline interferon from. I was hoping Intercat was associated with a different company, (hoping for a price reduction!). Oh well. Nina gg wrote: Hi Cherie, Sorry if there was any confusion regarding the links I sent!! The development of interferon was carried out by TORAY INDUSTRIES (Japan) The preparation of the active ingredient is done at TORAY (Japan) The active ingredient, i.e. the desalted bulk of interferon, is transported from Toray (Japan) to VIRBAC (FRANCE). It's the same 'stuff' that is being ordered by members on this list. Here is one of the messages from the felvlist archives..(1999). Cheers! Glenda Our FeLV/FIV kitties other stuff: http://community.webshots.com/user/sicky_icicle Feline interferon Cesar ( [EMAIL PROTECTED] ) Thu, 28 Oct 1999 12:17:51 -0700 Hi, Sue and all The problem we have with interferon (Intron-A) is that once it is prepared, it loses part of efficiency quickly (my vet says), therefore, we are attempting to verify what type of interferon you use which can be kept during so much time, and in spite of the fact Salamanca is a university city, unfortunately, there isn't vet school. :(( Concerning the possibility to obtain Intercat in USA or Europe, in the web page of Toray laboratory we can read: "Toray Gives Sole Developing and Marketing Rights for Intercat in Europe to France-Based Virbac Toray Industries, Inc., has announced that it has given rights to develop and market Intercat in Europe to Virbac S.A., of France. Intercat is drawing international attention as the world's first recombinant feline interferon agent for companion animals. Under the arrangement, Virbac will work with Toray in conducting clinical tests to acquire approval for Intercat from European authorities. Toray foresees considerable demand for Intercat in Europe, where the population of domesticated cats totals over 35 million -- almost 5 times the number in Japan. Headquartered in Nice, Virbac manufactures and markets pharmaceuticals for animals worldwide -- the fifth largest supplier in the world of such products for small animals. As part of its operations, Virbac is developing Leucogen, a recombinant feline leukemia vaccine that is already being marketed in Europe, USA and Japan. Through Kyoritsu Shoji K.K. (Headquarters: Tokyo; President:Yuriko Takai), Toray has been marketing Intercat in Japan since February 1994 as an antiviral agent effective against the infectious disease commonly known as cats' cold, which is caused by feline calicivirus. Development and marketing rights for Intercat in the Americas have been given to Schering-Plough Corp., of the United States, where the further development of Intercat is continuing." Well, I haven't found anything about Intercat at Schering-Plough laboratory but at Virbac web page WE CAN READ: "Interferon, the first veterinary antiviral agent. Developed by the Japanese company TORAY, interferon is a natural compound with antiviral properties.Used in Japan for calicivirosis in cats and parvovirosis in dogs, interferon has inspired great hopes among European veterinarians. In 1997, Virbac obtained exclusive rights for the distribution of this drug in Europe, and the rights for its application for other therapeutic indications." http://www.virbac.fr Why vets doesn't know this?. I will tell him IMMEDIATELLY!. If I would obtain more information, I will post. Greetings Cesar
RE: OT - We need your prayers
Hi, Nina. How is Zevon? -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Nina Sent: Monday, March 07, 2005 10:43 PM To: felvtalk@felineleukemia.org Subject: OT - We need your prayers Hi Everyone, Bruce and I just got back from the Vet. Our 8 year old German Shepherd Dog, Zevon has been having trouble with his back legs for the last couple of months. I guess I've been in denial and have been giving him stuff for arthritis etc. The vet (not his regular ortho surgeon, he's out of town at conferences), suspects either a disc problem or something called, Degenerative Myelopathy, (a degenerative neurologic disease), something GSDs are prone to apparently. He had to stay at the vet overnight to treat him intravenously with steroids to see if whatever is causing his paralysis lessens. The ER vet said that there is a chance that the steroid therapy alone could help him regain the full use of his legs, (let's hope so, tonight's therapy is costing over $1100 bucks and we haven't even started diagnostic work yet). If this doesn't help him, Bruce and I have a tough decision to make. About 4 years ago, Zevon took a leap off a very high cliff in Santa Barbara trying to get to the surf below. He sustained severe sprains on both his front legs and we were told by three vets to have him PTS before we found a surgeon that took on his case and saved his life. Zevon is a highly energetic dog that never lets pain get in his way of having a good time. The operations and months of recooperative down-stays were extremely hard on him. He is also vulnerable to reinjury of his front legs and now with his back legs in jeopardy, not to mention the fact that he's no longer a young dog, make his prognosis for a quality life in a wheel chair very poor. Please include him in your prayers. Please pray that tonight's treatment brings us a miracle of at least temporary recovery. He's so important to our household, we all love him so much, dogs, cats and humans alike. He's such a sweet soul, I don't know how we'd get along without him. Thanks for caring, Nina
Re: Some More Virbagen Omega Info
Here's some more info that applies to anemic FeLV cats: From the Product Information (http://www.emea.eu.int/vetdocs/PDFs/EPAR/virbagenomega/V-061-PI-en.pdf) file: in anaemic cats, mortality rate of about 60% at 4, 6, 9 and 12 months was reduced by approximately 30% following treatment with interferon. in non-anaemic cats, mortality rate of 50 % in cats infected by FeLV was reduced by 20% following treatment with interferon. In cats infected by FIV, mortality was low (5%) and was not influenced by the treatment. This one here is encouraging: http://vetinterferon.nexenservices.com/aff_abstract.php?id=141lang=eng. If you look at the chart on page 2, anemia got way better on day 14, but tapered back down at day 120. Still way up at day 60 though! Of course these are just two studies and we all know how that works. Other studies might say the exact opposite. Still encouraging though. -Kyle - Original Message - From: Melbeach To: felvtalk@felineleukemia.org Sent: Tuesday, March 08, 2005 8:04 PM Subject: Some More Virbagen Omega Info Found some more info on VO ya'll might be interested in. From Virbac's FAQ: http://www.virbagenomega.com/uk/faqcat Q: After reconstitution of Virbagen® Omega, can the vial be stored overnight and used on an animal the next day? A: Studies have demonstrated a stability of the molecule up to 3 weeks minimum at +4°C. Nevertheless, taking into consideration the fact that there is no preservative in the formulation of the product, the risk of contamination with fungus or bacteria exists. Nevertheless, if injections are performed in asepsis conditions (sterile needles...), the risk of contamination will be minimum. Q: Can Virbagen® Omega be frozen after reconstitution? A: Feline omega interferon is a glycoprotein which is very stable in general. After resuspension, stability studies showed that the solution was stable for at least 3 weeks at +4°C. According to knowledge on the molecule, it does not seem there is any risk linked to freezing the solution. Nevertheless, precise data concerning this type of storage are not available to date. In any case, several cycles of freezing-thawing are not recommended. The official pdf documents filed with the European Medicines Agency are here: http://www.emea.eu.int/vetdocs/vets/Epar/virbagenomega/virbagenomega.htm The "Scientific Discussion" is real detailed and informative. The "Product Information" looks like the official Product Insert info. Australian FDA info: http://www.apvma.gov.au/gazette/gazette0111p14.shtml A study where only 1 round of 5 injections was applied for FeLV, instead of the recommended 3 rounds: http://vetinterferon.nexenservices.com/aff_abstract.php?id=55lang=eng I was interested in possible interference with Immunoregulin and/or continuing with Immunoregulin after VO therapy is complete. The Scientific Discussion has a small blurb that says "Due to the indications for use, concomitant use of immunological products is not recommended." Yet interestingly, the Product Information is silent on this. So I emailed Virbac and they said: "Unfortunately, as far as I am aware, ImmunoRegulin is not available in Europe and we do not have any data on the use of it either concurrently with Virbagen Omega or before/after VO treatment. There are products available in Europe (Baypamun HK and Acemannan) that are similar in concept to ImmunoRegulin. My understanding of these products is that they work by inducing the production of endogenous cytokines (including Interferons) but that placebo controlled studies have failed to demonstrate a significant benefit of treatment with these products. On this basis I can see little benefit in continuing with ImmunoRegulin treatment as Virbagen Omega effectively bypasses the need to produce endogenous type 1 interferons and will stimulate an immunological cascade itself." Anyone know what that means? -Kyle
Additional Info on the Six Stages of FeLV infection
Kirk's Current Veterinary Therapy XIII Small Animal PracticeCVT Update: Feline Leukemia Virus pgs 281 Year Published: 2000 Dr. Alice M. Wolf, ACVIM, ABVP (Fe)(One of the Internal Medicine Consultants on the www.vin.com board.) PATHOGENESIS OF FELV Following infection, FeLV has a specific pattern or replication that affects the results of FeLV testing and the clinical signs that may be seen in an individual cat. STAGE I: Days 2 - 4Replication: In local lymphoid tissue (retropharyngeal, tonsil, gastrointestinal mucosal).Clinical Signs: None to mild viral (fever)FeLV status: All tests negative at this timePrognosis: Majority recover STAGE II: Days 1 - 14Replication: Few circulating lymphocytes and mononuclear cells (primary Viremia)Clinical Signs: None, or mild viral signsFeLV status: Serum ELISA becomes positive, PCR may be positive, (IFA, saliva, tears negative)Prognosis: Most recover, possible latency (6-30 mo) STAGE III Days 3 - 12Replication: Systemic lymphoid centers (germinal centers)Clinical Signs: None, or mild to moderate viral signsFeLV status: Serum ELISA positive, PCR positive, (IFA, saliva, tears negative) Prognosis: Recovery for many, possible future lymphosarcoma STAGE IV Days 7 - 21Replication: Bone marrow stem cells, epithelial cellsClinical Signs: Peripheral blood alterations, viral signsFeLV status: Serum ELISA, PCR, bone marrow IFA positive (peripheral-blood IFA positive or negative, saliva, tears negative)Prognosis: Likely to progress to persistent infection STAGE V Days 14 - 28Replication: Marrow origin, general viremiaClinical Signs: All associated hematologic and systemic FeLV signs possibleFeLV status: Serum ELISA, PCR, bone marrow, and peripheral-blood IFA positive (saliva, tears negative)Prognosis: Persistent Viremia, recovery from this stage of infection is rare STAGE VI Days 28 - ?Replication: Marrow Viremia, widespread epithelial and lymphoid replicationClinical Signs: Any associated with FeLV FeLV status: Serum ELISA, PCR, BM and peripheral blood IFA, ELISA on saliva and tears may be positive Prognosis: Long term prognosis is grave, 83% of cats die within 3.5 years in multicat households, longevity is increased for single cats with good veterinary care.
Re: OT - We need your prayers
Hi Hideyo, Thanks for asking about Zevon. He's really out of it because of his pain med patch, but we still have to watch him carefully because he refuses to recognize his limitations. He's suppose to be on 6 to 8 weeks of crate rest. It's very hard on him to not be able to follow us around the house, or run to the window to bark at anyone with the nerve to walk by. We still don't know if the steroid therapy has helped. We're having to use a support strap to allow him to walk because he can't put weight on his back legs and they splay out from under him. This morning I watched while my husband took him out to relieve himself, (the dog, not my husband!). I watched in horror while Zevon squatted to urinate as Bruce continued to support him with the strap. Of course, Z peed all over our new, expensive support strap! Nothing lasts long in this house! He has refused food and hasn't eaten since Monday at 4:30pm. (except for a bit of dog biscuit which he held in his mouth for 30 seconds before deciding it was a good idea to chew and eat it). I'm thinking it's because of the fentanyl patch. I may remove it early and see if it helps. Nina Hideyo Yamamoto wrote: Hi, Nina. How is Zevon? -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Nina Sent: Monday, March 07, 2005 10:43 PM To: felvtalk@felineleukemia.org Subject: OT - We need your prayers Hi Everyone, Bruce and I just got back from the Vet. Our 8 year old German Shepherd Dog, Zevon has been having trouble with his back legs for the last couple of months. I guess I've been in denial and have been giving him stuff for arthritis etc. The vet (not his regular ortho surgeon, he's out of town at conferences), suspects either a disc problem or something called, Degenerative Myelopathy, (a degenerative neurologic disease), something GSDs are prone to apparently. He had to stay at the vet overnight to treat him intravenously with steroids to see if whatever is causing his paralysis lessens. The ER vet said that there is a chance that the steroid therapy alone could help him regain the full use of his legs, (let's hope so, tonight's therapy is costing over $1100 bucks and we haven't even started diagnostic work yet). If this doesn't help him, Bruce and I have a tough decision to make. About 4 years ago, Zevon took a leap off a very high cliff in Santa Barbara trying to get to the surf below. He sustained severe sprains on both his front legs and we were told by three vets to have him PTS before we found a surgeon that took on his case and saved his life. Zevon is a highly energetic dog that never lets pain get in his way of having a good time. The operations and months of recooperative down-stays were extremely hard on him. He is also vulnerable to reinjury of his front legs and now with his back legs in jeopardy, not to mention the fact that he's no longer a young dog, make his prognosis for a quality life in a wheel chair very poor. Please include him in your prayers. Please pray that tonight's treatment brings us a miracle of at least temporary recovery. He's so important to our household, we all love him so much, dogs, cats and humans alike. He's such a sweet soul, I don't know how we'd get along without him. Thanks for caring, Nina
Re: Additional Info on the Six Stages of FeLV infection
Glenda, Thank you very much for the stage info. I'm not sure I believe the "time-line" used though. I think the advancement of stages is much more related to individual cats than indicated, otherwise we'd have a much better idea how long it takes to develop critical symptoms. I still feel strongly that if we can administer feline interferon before stage four, (before a positive reading on an IFA), it might help boost their immune systems enough to clear the disease. I'd love to see a study on this. We should contact Virbagen or research vets to see if anyone is interested in conducting such a study. Nina gg wrote: Kirk's Current Veterinary Therapy XIII Small Animal Practice CVT Update: Feline Leukemia Virus pgs 281 Year Published: 2000 Dr. Alice M. Wolf, ACVIM, ABVP (Fe) (One of the Internal Medicine Consultants on the www.vin.com board.) PATHOGENESIS OF FELV Following infection, FeLV has a specific pattern or replication that affects the results of FeLV testing and the clinical signs that may be seen in an individual cat. STAGE I: Days 2 - 4 Replication: In local lymphoid tissue (retropharyngeal, tonsil, gastrointestinal mucosal). Clinical Signs: None to mild viral (fever) FeLV status: All tests negative at this time Prognosis: Majority recover STAGE II: Days 1 - 14 Replication: Few circulating lymphocytes and mononuclear cells (primary Viremia) Clinical Signs: None, or mild viral signs FeLV status: Serum ELISA becomes positive, PCR may be positive, (IFA, saliva, tears negative) Prognosis: Most recover, possible latency (6-30 mo) STAGE III Days 3 - 12 Replication: Systemic lymphoid centers (germinal centers) Clinical Signs: None, or mild to moderate viral signs FeLV status: Serum ELISA positive, PCR positive, (IFA, saliva, tears negative) Prognosis: Recovery for many, possible future lymphosarcoma STAGE IV Days 7 - 21 Replication: Bone marrow stem cells, epithelial cells Clinical Signs: Peripheral blood alterations, viral signs FeLV status: Serum ELISA, PCR, bone marrow IFA positive (peripheral-blood IFA positive or negative, saliva, tears negative) Prognosis: Likely to progress to persistent infection STAGE V Days 14 - 28 Replication: Marrow origin, general viremia Clinical Signs: All associated hematologic and systemic FeLV signs possible FeLV status: Serum ELISA, PCR, bone marrow, and peripheral-blood IFA positive (saliva, tears negative) Prognosis: Persistent Viremia, recovery from this stage of infection is rare STAGE VI Days 28 - ? Replication: Marrow Viremia, widespread epithelial and lymphoid replication Clinical Signs: Any associated with FeLV FeLV status: Serum ELISA, PCR, BM and peripheral blood IFA, ELISA on saliva and tears may be positive Prognosis: Long term prognosis is grave, 83% of cats die within 3.5 years in multicat households, longevity is increased for single cats with good veterinary care.
FIV positive list question (Cross Posting)
Cross Posting: Do Not Reply To Me In a message dated 3/9/2005 3:01:39 PM Pacific Standard Time, [EMAIL PROTECTED] writes: Is there a special list to find help for FIV+ cats that need placement.This guy is a real big guy (Maine Coon) but like a big ole teddy bear -the sweetest can be.Terri--Terri Durham-StoneSafe a Life "Spay and Neuter"Live well, Love much, Laugh Often Terrie MohrCheck site for available Siameses for adoption!More will be posted soon.http://www.tazzys-siameses-collies.petfinder.org/http://groups.yahoo.com/group/wasiameserescuehttp://hometown.aol.com/tatorbunz/index.htmlhttp://hometown.aol.com/tatorbunz/myhomepage/petmemorial.htmlTAZZY'S ANIMAL TRANSPORTSSIAMESE COLLIE RESCUEOwner/DriverPetfinder.comAdopt a Homeless Pet!http://www.petfinder.com/http://www.orecatay.com/http://www.awca.net/index.htmhttp://www.felineleukemia.org/http://www.petloss.com/http://www.meezer.com/http://thesiamesestore.com/http://tx.siameserescue.org/adopt.htmlhttp://ca.siameserescue.org/http://co.siameserescue.org/http://va.siameserescue.org/ inline: aks.jpginline: logobuttonsq.jpg
RE: Help with medicating/pilling/ feline interferon
I would like to apply for it, but never found out exactly what I needed to I called the phone number on the archive, but no one called me back. Do you know what process I need to take? Thank you! Hideyo -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of [EMAIL PROTECTED] Sent: Wednesday, March 09, 2005 1:45 PM To: felvtalk@felineleukemia.org Subject: Re: Help with medicating/pilling/ feline interferon As for pilling, I have a lot of luck with covering the pill in Nutrical before pilling. It tastes good to them and lubricates it, and also makes it stick to their mouth when you pill them so harder to spit out. I was also thinking of Nina's idea-- that those of us who can afford it try to keep some VO on hand so when any of us are in an emergency someone will have it and can send it (with reimbursement, of course). I had 3 boxes that were supposed to be for Simon but arrived too late. I sent one to Kyle. I have 2 more I am holding on to. I will see if my regular vet can apply for it for Lucy so I can get more, in which case I could send more to people in emergency situations. But I want to keep some on hand. I would suggest everyone who can afford it start the process and at least get the application approved, even if not ordering the medicine, so that it is only a 2 week wait instead of 2 month wait if you or someone else needs it. Michelle In a message dated 3/9/05 3:40:15 PM Eastern Standard Time, [EMAIL PROTECTED] writes: Another hint; after you get approval, have your vet send in another application. That way you have an approved app waiting for you should you decide to order more. Maybe we should all do this for each other on the list. That way those in crisis will have feline interferon when they need it most.
RE: Uh-oh-oh update -pls help!!
I just talked to my vet about Uh-oh-ohs low RBC and she told me not to worry about it his HCT is good and she has seen lower RBC and he is going to be fine so I will just keep an eye on him for now. Thank you! Hideyo -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of [EMAIL PROTECTED] Sent: Wednesday, March 09, 2005 1:09 PM To: felvtalk@felineleukemia.org Subject: Re: Uh-oh-oh update -pls help!! I think the rise in his HCT is very, very good. Michelle By the way, his HCT was up from 25 (thats when he got sick in January) to 32.
Re: Help with medicating/pilling/ feline interferon
Your vet needs to send an application for special dispensation (approval to import) to the FDA. There is an email in the archives (I can find it and send it if you can't-- I saved it somewhere on my computer) that has the info the vet needs to send. The FDA then takes about a month or so to approve it (I recommend hassling them after a few weeks) and faxes the approval to your vet (if you ask for it to be faxed). Your vet can then order the VO from England. The order form is in another email which I saved somewhere. Let me know if you want me to send it. Michelle In a message dated 3/9/05 5:13:26 PM, [EMAIL PROTECTED] writes: Great idea Michelle, I know we have talked about it before but, where do I start with the application process. Thanks Cherie
Re: Uh-oh-oh update -pls help!!
That's great news! Michelle In a message dated 3/9/05 6:43:22 PM, [EMAIL PROTECTED] writes: I just talked to my vet about Uh-oh-oh's low RBC - and she told me not to worry about it - his HCT is good and she has seen lower RBC - and he is going to be fine - so I will just keep an eye on him for now. Thank you! Hideyo
Re: Feline Interferon
Dear Michelle: How thoughtful of you to share some of your VO with Kyle. Is it helping? Stockpiling the stuff is a good strategy, would that I could afford to do so. For now it is all I can do just to afford the immune-boosting supplements. Now if I could win that pie in the sky lottery (but can't afford to buy tickets for that, either) I could buy stock in the company, or maybe bribe someone in the FDA. I keep hoping and praying if and when my two remaining positives may need some, I will be able to afford it and one of you less financially challenged listmembers may have some on hand to spare that I could buy. They really need to do some more studies to determine if this is a reliable treatment for helping an FeLV+ cat in stage 1-4 to seroconvert. And what it can and can't do to reliably benefit those cats who are already stage 5 and persistently viremic, or stage 6 and crashing. I've been told it IS possible to determine which subgroup of virus cats are infected with, but this is only germane in a research setting. And it is possible using the ELISA and IFA tests to determine which cats are still in the very early stages of infection or already have it settled in their bone marrow. Do you think we could find someone at a vet institution who would be interested in monitoring some home trials? Lord knows we have an ample supply of study candidates on this list. I don't suppose the company would be willing to provide the VO at a reduced cost, by any chance? Dream on. lSally in San Jose
feline interferon-- how to seek approval to import from FDA
Here is the info from an old posting: Dear Ms. Meyer: This is in response to your e-mail inquiry to the Center for Veterinary Medicine home page concerning the importation of a drug that is not approved in the U.S. FDA's Center for Veterinary Medicine grants permission on limited basis to allow small amounts of unapproved animal drugs to enter the U.S. Permission to import drugs for patient use will be granted subject to the unavailability of suitable FDA approved (human or veterinarian) drugs; either because of shortages; or because drugs are unavailable in the U.S. to give a suitable therapeutic result. Secondly, permission is only granted in those instances where the drug is considered as medically necessary veterinary drug. A veterinarian would need to make a formal request in writing to import the drug. It is also important to note that to import a drug; the animal must be under professional medical care through a valid veterinarian-client-patient relationship. Prescription orders will be limited to a 90-day supply/pet. Prescription renewals will need to be re-requested this office for additional 90-day supplies. The letter should include the veterinarian clinic's letterhead, his or her signature and the following information: Veterinarian name, address and phone number Clinic name and address Client's name and address Patient name and species Name of Drug Drug Family or class Name and address of drug supplier Legal status of the drug in the foreign country Amount to be imported (non-commercial quantity) Disease condition to be treated Reason why an approved human or animal drug will not treat the disease condition A statement that: o you will notify the owner that the drug is not approved o that the drug will not be use of food animals And that you will notify FDA if the are any adverse reactions How did you learn about the existence of this drug? As part of FDA's regulatory discretion FDA may cancel permission at any time. Generally, rescinding permission to import medically necessary drugs is based upon new scientific information and knowledge about new or current therapies available in the U.S. such as new drug approvals. Please refer all inquiries and status questions at the address below: Ms. Toni Wooten Division of Compliance, HFV-236 Center for Veterinary Medicine Food Drug Administration Metro Park North 7500 Standish Place Rockville, MD 20855 301-594-0796 FAX 301-827-1498 I hope this is helpful. Sincerely yours, FDA/CVM Home Page
Re: Help with medicating/pilling/ feline interferon
I posted the info on how to apply to the FDA, how to order from Abbey Vet, and a data sheet to give to your vet -- in 3 separate emails. However, at least two of the emails are awaiting approval by the moderator before they will show up on the list, because of the PDF attachments, I guess. But you should get the info soon. Michelle
Re: feline interferon-- how to seek approval to import from FDA
Thank you Michelle, I will forward the information to my vetjust precautionaryCherie[EMAIL PROTECTED] wrote: Here is the info from an old posting: Dear Ms. Meyer: This is in response to your e-mail inquiry to the Center for Veterinary Medicine home page concerning the importation of a drug that is not approved in the U.S. FDA's Center for Veterinary Medicine grants permission on limited basis to allow small amounts of unapproved animal drugs to enter the U.S. Permission to import drugs for patient use will be granted subject to the unavailability of suitable FDA approved (human or veterinarian) drugs; either because of shortages; or because drugs are unavailable in the U.S. to give a suitable therapeutic result. Secondly, permission is only granted in those instances where the drug is considered as medically necessary veterinary drug. A veterinarian would need to make a formal request in writing to import the drug. It is also important to note that to import a drug; the animal must be under professional medical care through a valid veterinarian-client-patient relationship. Prescription orders will be limited to a 90-day supply/pet. Prescription renewals will need to be re-requested this office for additional 90-day supplies. The letter should include the veterinarian clinic's letterhead, his or her signature and the following information: Veterinarian name, address and phone number Clinic name and address Client's name and address Patient name and species Name of Drug Drug Family or class Name and address of drug supplier Legal status of the drug in the foreign country Amount to be imported (non-commercial quantity) Disease condition to be treated Reason why an approved human or animal drug will not treat the disease condition A statement that: o you will notify the owner that the drug is not approved o that the drug will not be use of food animals And that you will notify FDA if the are any adverse reactions How did you learn about the existence of this drug? As part of FDA's regulatory discretion FDA may cancel permission at any time. Generally, rescinding permission to import medically necessary drugs is based upon new scientific information and knowledge about new or current therapies available in the U.S. such as new drug approvals. Please refer all inquiries and status questions at the address below: Ms. Toni Wooten Division of Compliance, HFV-236 Center for Veterinary Medicine Food Drug Administration Metro Park North 7500 Standish Place Rockville, MD 20855 301-594-0796 FAX 301-827-1498 I hope this is helpful. Sincerely yours, FDA/CVM Home Page
Anakin is gone
When I took him to the vet he could not even stand.The vet said most of the medication won't help he's to for gone most take time to work he doesn't time.She said he was not getting enough blood to his heart he has a heart murmur.Shesaid his kidneys were alot smaller.She went totake abit of blood he didn't even move,but she said there was so little blood left in himshe couldn't.She said that the best thingwe could do for him is topts.So we all said it was time,We said our good bye's I stayed with him when she put the needle in he didn't even move.I stayed there patting him tell him how much we love him.It's so hard.Thank you all so much for everything.Anakin iswith all our fur babies thehave past. Love Anita
Re: Anakin is gone
I'm so sorry for your loss. I've cried so many tears over my baby Tip and when I read of another loss it starts all over again. You were lucky to have your special Anakin and he was so blessed to have you to love and care for him. Try to remember only the good times and know that he is happy and healthy and waiting to be with you again someday. Love, Sheila inline: Clouds.jpg
Re: Anakin is gone
I'm so sorry Anita. I know it must by so hard to go through. Take care. Kathycatstevens [EMAIL PROTECTED] wrote: When I took him to the vet he could not even stand.The vet said most of the medication won't help he's to for gone most take time to work he doesn't time.She said he was not getting enough blood to his heart he has a heart murmur.Shesaid his kidneys were alot smaller.She went totake abit of blood he didn't even move,but she said there was so little blood left in himshe couldn't.She said that the best thingwe could do for him is topts.So we all said it was time,We said our good bye's I stayed with him when she put the needle in he didn't even move.I stayed there patting him tell him how much we love him.It's so hard.Thank you all so much for everything.Anakin iswith all our fur babies thehave past. Love Anita
Re: Anakin is gone
I'm so sorry. You did all you could and he loved you dearly. I'm sure he knew he was loved and he's at peace. I feel so bad for you. I know it's hard. Just try to remember that others are herethat care for you and feel your loss. Be at peace yourself and remember him as a happy and loved baby. Kristinacatstevens [EMAIL PROTECTED] wrote: When I took him to the vet he could not even stand.The vet said most of the medication won't help he's to for gone most take time to work he doesn't time.She said he was not getting enough blood to his heart he has a heart murmur.Shesaid his kidneys were alot smaller.She went totake abit of blood he didn't even move,but she said there was so little blood left in himshe couldn't.She said that the best thingwe could do for him is topts.So we all said it was time,We said our good bye's I stayed with him when she put the needle in he didn't even move.I stayed there patting him tell him how much we love him.It's so hard.Thank you all so much for everything.Anakin iswith all our fur babies thehave past. Love Anita
