Thanks!!. It is working normally now...phew.

Lik Wee

On Wed, Mar 10, 2010 at 4:46 PM, Brian Pratt <[email protected]>wrote:

> It's a windows thing: ControlPanel|System|Advanced|EnvironmentVariables
>
> Good luck!
>
> Brian
>
> On Wed, Mar 10, 2010 at 4:33 PM, Lik Wee Lee <[email protected]>wrote:
>
>> I am not sure how to do this.
>> There is a section in the apache httpd.conf that shows:
>> Should I just delete either one of the PassEnv WEBSERVER_ROOT? Thanks.
>>
>> #
>> # Begin settings for the Trans Proteomic Pipeline
>> #
>>
>> # Add 5-hour timeout
>> Timeout 18000
>>
>> Alias /tpp-bin "C:/Inetpub/tpp-bin"
>> <Directory "C:/Inetpub/tpp-bin">
>>     Options Indexes MultiViews ExecCGI
>>     AllowOverride None
>>     Order allow,deny
>>     Allow from all
>>
>>     AddHandler cgi-script .cgi .pl
>>     ScriptInterpreterSource Registry
>>
>>     PassEnv WEBSERVER_ROOT
>>     PassEnv WEBSERVER_TMP
>> </Directory>
>>
>> Alias /ISB "C:/Inetpub/wwwroot/ISB"
>>
>> Alias /schema "C:/Inetpub/wwwroot/schema"
>>
>> <Directory "C:/Inetpub/wwwroot">
>>     Options Indexes MultiViews Includes
>>     AllowOverride None
>>     Order allow,deny
>>     Allow from all
>>
>>     AddType text/html .shtml
>>     AddHandler server-parsed .shtml
>>
>>     PassEnv WEBSERVER_ROOT
>>     PassEnv WEBSERVER_TMP
>> </Directory>
>> #
>> # End settings for the Trans Proteomic Pipeline
>> #
>>
>>   On Wed, Mar 10, 2010 at 4:21 PM, Brian Pratt <[email protected]
>> > wrote:
>>
>>>   ah, wait, I do see one weird thing:
>>>
>>> WEBSERVER_ROOT = c:\Inetpub\wwwroot;c:\Inetpub\wwwroot
>>>
>>> change that environment variable to
>>>
>>> WEBSERVER_ROOT = c:\Inetpub\wwwroot
>>>
>>> and see how it goes.
>>>
>>>   On Wed, Mar 10, 2010 at 4:18 PM, Lik Wee Lee 
>>> <[email protected]>wrote:
>>>
>>>>  Nope. I installed it recently and it complained about missing perl so
>>>> I downloaded 5.10 and installed it successfully.
>>>> But when I ran into problems, I thought it might be due to the perl
>>>> version, so I uninstall Perl 5.10.1 and TPP and then reinstall Perl
>>>> 5.8.9 and TPP.
>>>>
>>>> Lik Wee
>>>>
>>>>   On Wed, Mar 10, 2010 at 4:08 PM, Brian Pratt <
>>>> [email protected]> wrote:
>>>>
>>>>>  Did you have a working TPP installation before?
>>>>>
>>>>>   On Wed, Mar 10, 2010 at 3:54 PM, Lik Wee Lee <
>>>>> [email protected]> wrote:
>>>>>
>>>>>>  Hi Brian,
>>>>>>
>>>>>>  On Wed, Mar 10, 2010 at 3:34 PM, Brian Pratt <
>>>>>> [email protected]> wrote:
>>>>>>
>>>>>>> I think the fact that run_in doesn't work indicates some kind of
>>>>>>> system level problem that's going to make everything else flaky.  Perl
>>>>>>> shouldn't be an issue, at least at this point.
>>>>>>>
>>>>>>> So "c:\inetpub\tpp-bin\run_in c:\; dir" doesn't work for you?
>>>>>>>
>>>>>>
>>>>>> I still get  command "dir" failed: Unknown error
>>>>>>
>>>>>>>
>>>>>>> What do you see when you type this into your browser address bar?
>>>>>>> http://localhost/tpp-bin/check_env.pl
>>>>>>>
>>>>>>>
>>>>>>
>>>>>> SCRIPT_NAME = /tpp-bin/check_env.pl
>>>>>> SERVER_NAME = localhost
>>>>>> HTTP_ACCEPT_ENCODING = gzip,deflate
>>>>>> HTTP_CONNECTION = keep-alive
>>>>>> REQUEST_METHOD = GET
>>>>>> SYSTEMROOT = C:\WINDOWS
>>>>>> HTTP_ACCEPT =
>>>>>> text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8
>>>>>> SCRIPT_FILENAME = C:/Inetpub/tpp-bin/check_env.pl
>>>>>> COMSPEC = C:\WINDOWS\system32\cmd.exe
>>>>>> SERVER_SOFTWARE = Apache/2.2.8 (Win32)
>>>>>> HTTP_ACCEPT_CHARSET = ISO-8859-1,utf-8;q=0.7,*;q=0.7
>>>>>> WINDIR = C:\WINDOWS
>>>>>> QUERY_STRING =
>>>>>> REMOTE_PORT = 3227
>>>>>> PATHEXT = .COM;.EXE;.BAT;.CMD;.VBS;.VBE;.JS;.JSE;.WSF;.WSH
>>>>>> HTTP_USER_AGENT = Mozilla/5.0 (Windows; U; Windows NT 5.1; en-US;
>>>>>> rv:1.9.0.18) Gecko/2010020220 Firefox/3.0.18 (.NET CLR 3.5.30729)
>>>>>> SERVER_PORT = 80
>>>>>> SERVER_SIGNATURE =
>>>>>> HTTP_ACCEPT_LANGUAGE = en-us,en;q=0.5
>>>>>> HTTP_COOKIE =
>>>>>> TPPSession=TYBEEDEHS:guest:249069786675ffea98006f8c1b444fa1
>>>>>> REMOTE_ADDR = 127.0.0.1
>>>>>> WEBSERVER_ROOT = c:\Inetpub\wwwroot;c:\Inetpub\wwwroot
>>>>>> HTTP_KEEP_ALIVE = 300
>>>>>> SERVER_PROTOCOL = HTTP/1.1
>>>>>> PATH = C:\Inetpub\tpp-bin;C:\Xcalibur\system\programs;C:\Program
>>>>>> Files\Thermo\Foundation;C:\Perl\site\bin;C:\Perl\bin;C:\WINDOWS\system32;C:\WINDOWS;C:\WINDOWS\System32\Wbem;C:\Program
>>>>>> Files\Common Files\Adaptec Shared\System;C:\Program Files\Analyst\bin
>>>>>> REQUEST_URI = /tpp-bin/check_env.pl
>>>>>> GATEWAY_INTERFACE = CGI/1.1
>>>>>> SERVER_ADDR = 127.0.0.1
>>>>>> DOCUMENT_ROOT = C:/Program Files/Apache Software
>>>>>> Foundation/Apache2.2/htdocs
>>>>>> HTTP_HOST = localhost
>>>>>>
>>>>>> Thanks for your help,
>>>>>> Lik Wee
>>>>>>
>>>>>>
>>>>>>>   It should give you a bunch of info including the PATH setting for
>>>>>>> your webserver.
>>>>>>>
>>>>>>>   On Wed, Mar 10, 2010 at 2:47 PM, Lik Wee Lee <
>>>>>>> [email protected]> wrote:
>>>>>>>
>>>>>>>>  Hi Jimmy,
>>>>>>>>
>>>>>>>> Yes, I also checked the .tandem file there were peptides with low
>>>>>>>> expect score.
>>>>>>>> I also looked at the .pep.xml file and checked that the scans,
>>>>>>>> hyperscore,
>>>>>>>> nextscore, bscore, ... matched the .tandem file.
>>>>>>>>
>>>>>>>> I am puzzled why the run_in doesn't work and wondering if this is
>>>>>>>> affecting
>>>>>>>> the xinteract command as well. any ideas?
>>>>>>>>
>>>>>>>> Lik Wee
>>>>>>>>
>>>>>>>>
>>>>>>>> On Wed, Mar 10, 2010 at 2:20 PM, Jimmy Eng <[email protected]>wrote:
>>>>>>>>
>>>>>>>>> I suggest you start debugging the problem one step at a time.
>>>>>>>>> First confirm that your Tandem search actually ran by looking at
>>>>>>>>> contents of the .tandem file.
>>>>>>>>> Next, check contents of tandem.pep.xml.
>>>>>>>>> Do both of these files look like they have peptide IDs in them?
>>>>>>>>>
>>>>>>>>>
>>>>>>>>>
>>>>>>>>> On Wed, Mar 10, 2010 at 2:04 PM, Lik Wee Lee <
>>>>>>>>> [email protected]> wrote:
>>>>>>>>> > Furthermore, I also did:
>>>>>>>>> > C:\Inetpub\wwwroot\ISB\data\17mix>c:\Inetpub\tpp-bin\Tandem2XML
>>>>>>>>> >
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem
>>>>>>>>> >
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>>>>>> >
>>>>>>>>> > but if I tried to browse file in petunia and click on [PepXML],
>>>>>>>>> > it opens a new window:
>>>>>>>>> >
>>>>>>>>> http://localhost/tpp-bin/PepXMLViewer.cgi?xmlFileName=c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>>>>>> >
>>>>>>>>> > but with the message:
>>>>>>>>> >
>>>>>>>>> > error:
>>>>>>>>> > can't open html
>>>>>>>>> >
>>>>>>>>> templatec:/Inetpub/wwwroot;c:/Inetpub/wwwroot/ISB/html/PepXMLViewer.html
>>>>>>>>> >
>>>>>>>>> > I also had problem with xinteract:
>>>>>>>>> >
>>>>>>>>> >
>>>>>>>>> C:\Inetpub\wwwroot\ISB\data\17mix\tandem>c:\Inetpub\tpp-bin\xinteract
>>>>>>>>> > -Ninteract.pep.xml -p0.05 -l7 -O
>>>>>>>>> >
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>>>>>> >
>>>>>>>>> > c:\Inetpub\tpp-bin\xinteract (TPP v4.3 JETSTREAM rev 1, Build
>>>>>>>>> 200909091257
>>>>>>>>> > (MinGW))
>>>>>>>>> >
>>>>>>>>> > running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>>>>>> >
>>>>>>>>> "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tand
>>>>>>>>> > em.pep.xml" -L"7""
>>>>>>>>> >
>>>>>>>>> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>>>>>> >
>>>>>>>>> "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
>>>>>>>>> > m.pep.xml" -L"7"" failed: Unknown error
>>>>>>>>> >
>>>>>>>>> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>>>>>> >
>>>>>>>>> "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
>>>>>>>>> > m.pep.xml" -L"7"" exited with non-zero exit code: -1
>>>>>>>>> > QUIT - the job is incomplete
>>>>>>>>> >
>>>>>>>>> >
>>>>>>>>> >
>>>>>>>>> > Is this an installation issue? Any ideas?
>>>>>>>>> >
>>>>>>>>> > Thanks,
>>>>>>>>> > Lik Wee
>>>>>>>>> >
>>>>>>>>> > On Wed, Mar 10, 2010 at 1:53 PM, Lik Wee Lee <
>>>>>>>>> [email protected]>
>>>>>>>>> > wrote:
>>>>>>>>> >>
>>>>>>>>> >> Hi Brian,
>>>>>>>>> >>
>>>>>>>>> >> The full path still gives command "..." failed: unknown error.
>>>>>>>>> >>
>>>>>>>>> >> I tried "run_in c:" and didn't get any output.
>>>>>>>>> >>
>>>>>>>>> >> But if I try "run_in c:\; dir", I get:
>>>>>>>>> >> command "dir" failed: Unknown error.
>>>>>>>>> >>
>>>>>>>>> >> Could it be I previously had installed Perl 5.10? I uninstalled
>>>>>>>>> it
>>>>>>>>> >> and then installed Perl 5.8.9 followed by tpp 4.3.1.
>>>>>>>>> >>
>>>>>>>>> >> Lik Wee
>>>>>>>>> >>
>>>>>>>>> >> On Wed, Mar 10, 2010 at 1:34 PM, Brian Pratt <
>>>>>>>>> [email protected]>
>>>>>>>>> >> wrote:
>>>>>>>>> >>>
>>>>>>>>> >>> "run_in" is just a little program that runs one or more
>>>>>>>>> commands in the
>>>>>>>>> >>> indicated directory.  For example "run_in c:\foo; bar.exe;
>>>>>>>>> baz.exe" performs
>>>>>>>>> >>> "cd c:\foo" then runs "bar.exe" then "baz.exe".  It exists to
>>>>>>>>> help with
>>>>>>>>> >>> linux-oriented multipart command lines in the GUI, statements
>>>>>>>>> like "cd
>>>>>>>>> >>> c:foo; bar.exe; baz.exe" (we just swap "run_in" for "cd" on the
>>>>>>>>> windows
>>>>>>>>> >>> installation).
>>>>>>>>> >>>
>>>>>>>>> >>> Anyway, that's what it's for - why it doesn't work for you is a
>>>>>>>>> mystery.
>>>>>>>>> >>> Perhaps it's a path issue: how does the command line
>>>>>>>>> >>> c:\Inetpub\tpp-bin\run_in
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>>>>>> >>> c:\Inetpub\tpp-bin\tandem
>>>>>>>>> >>>
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>>>>>> >>>
>>>>>>>>> >>> work for you (that is, with full path to run_in specified)?
>>>>>>>>> >>>
>>>>>>>>> >>> On Wed, Mar 10, 2010 at 1:21 PM, Lik Wee Lee <
>>>>>>>>> [email protected]>
>>>>>>>>> >>> wrote:
>>>>>>>>> >>>>
>>>>>>>>> >>>> Hi,
>>>>>>>>> >>>>
>>>>>>>>> >>>> When I tried to do a xtandem search in the TPP petunia
>>>>>>>>> interface,
>>>>>>>>> >>>> I encountered the problem:
>>>>>>>>> >>>>
>>>>>>>>> >>>> # Commands for session TYBEEDEHS on Wed Mar 10 13:13:38 2010
>>>>>>>>> >>>> # BEGIN COMMAND BLOCK
>>>>>>>>> >>>> ###### BEGIN Command Execution ######
>>>>>>>>> >>>>
>>>>>>>>> >>>> [Wed Mar 10 13:13:38 2010] EXECUTING: run_in
>>>>>>>>> >>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>>>>>> c:\Inetpub\tpp-bin\tandem
>>>>>>>>> >>>>
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>>>>>> >>>> OUTPUT:
>>>>>>>>> >>>>
>>>>>>>>> >>>> command "c:\Inetpub\tpp-bin\tandem
>>>>>>>>> >>>>
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params"
>>>>>>>>> >>>> failed: Unknown error
>>>>>>>>> >>>>
>>>>>>>>> >>>>
>>>>>>>>> >>>>
>>>>>>>>> >>>>
>>>>>>>>> >>>> END OUTPUT
>>>>>>>>> >>>> RETURN CODE:65280
>>>>>>>>> >>>> ###### End Command Execution ######
>>>>>>>>> >>>> # All finished at Wed Mar 10 13:13:38 2010
>>>>>>>>> >>>> # END COMMAND BLOCK
>>>>>>>>> >>>>
>>>>>>>>> >>>> Does anyone have any ideas why this occur?
>>>>>>>>> >>>> However, the search was performed successfully if I did it by
>>>>>>>>> command
>>>>>>>>> >>>> line:
>>>>>>>>> >>>>
>>>>>>>>> >>>> c:\Inetpub\tpp-bin\tandem
>>>>>>>>> >>>>
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>>>>>> >>>>
>>>>>>>>> >>>> If I try
>>>>>>>>> >>>>
>>>>>>>>> >>>> run_in c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>>>>>> >>>> c:\Inetpub\tpp-bin\tandem
>>>>>>>>> >>>>
>>>>>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>>>>>> >>>>
>>>>>>>>> >>>> it says command failed: Unknown error.
>>>>>>>>> >>>>
>>>>>>>>> >>>> I have ActivePerl 5.8.9 build 827 and TPP version 4.3.1
>>>>>>>>> installed on
>>>>>>>>> >>>> Windows XP SP3.
>>>>>>>>> >>>>
>>>>>>>>> >>>> Thanks,
>>>>>>>>> >>>> Lik Wee
>>>>>>>>> >>>>
>>>>>>>>> >>>> --
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