Hi Jimmy,

Yes, I also checked the .tandem file there were peptides with low expect
score.
I also looked at the .pep.xml file and checked that the scans, hyperscore,
nextscore, bscore, ... matched the .tandem file.

I am puzzled why the run_in doesn't work and wondering if this is affecting
the xinteract command as well. any ideas?

Lik Wee

On Wed, Mar 10, 2010 at 2:20 PM, Jimmy Eng <[email protected]> wrote:

> I suggest you start debugging the problem one step at a time.
> First confirm that your Tandem search actually ran by looking at
> contents of the .tandem file.
> Next, check contents of tandem.pep.xml.
> Do both of these files look like they have peptide IDs in them?
>
>
>
> On Wed, Mar 10, 2010 at 2:04 PM, Lik Wee Lee <[email protected]>
> wrote:
> > Furthermore, I also did:
> > C:\Inetpub\wwwroot\ISB\data\17mix>c:\Inetpub\tpp-bin\Tandem2XML
> > c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem
> >
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
> >
> > but if I tried to browse file in petunia and click on [PepXML],
> > it opens a new window:
> >
> http://localhost/tpp-bin/PepXMLViewer.cgi?xmlFileName=c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
> >
> > but with the message:
> >
> > error:
> > can't open html
> > templatec:/Inetpub/wwwroot;c:/Inetpub/wwwroot/ISB/html/PepXMLViewer.html
> >
> > I also had problem with xinteract:
> >
> > C:\Inetpub\wwwroot\ISB\data\17mix\tandem>c:\Inetpub\tpp-bin\xinteract
> > -Ninteract.pep.xml -p0.05 -l7 -O
> >
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
> >
> > c:\Inetpub\tpp-bin\xinteract (TPP v4.3 JETSTREAM rev 1, Build
> 200909091257
> > (MinGW))
> >
> > running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tand
> > em.pep.xml" -L"7""
> >
> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
> > m.pep.xml" -L"7"" failed: Unknown error
> >
> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
> > m.pep.xml" -L"7"" exited with non-zero exit code: -1
> > QUIT - the job is incomplete
> >
> >
> >
> > Is this an installation issue? Any ideas?
> >
> > Thanks,
> > Lik Wee
> >
> > On Wed, Mar 10, 2010 at 1:53 PM, Lik Wee Lee <[email protected]>
> > wrote:
> >>
> >> Hi Brian,
> >>
> >> The full path still gives command "..." failed: unknown error.
> >>
> >> I tried "run_in c:" and didn't get any output.
> >>
> >> But if I try "run_in c:\; dir", I get:
> >> command "dir" failed: Unknown error.
> >>
> >> Could it be I previously had installed Perl 5.10? I uninstalled it
> >> and then installed Perl 5.8.9 followed by tpp 4.3.1.
> >>
> >> Lik Wee
> >>
> >> On Wed, Mar 10, 2010 at 1:34 PM, Brian Pratt <[email protected]
> >
> >> wrote:
> >>>
> >>> "run_in" is just a little program that runs one or more commands in the
> >>> indicated directory.  For example "run_in c:\foo; bar.exe; baz.exe"
> performs
> >>> "cd c:\foo" then runs "bar.exe" then "baz.exe".  It exists to help with
> >>> linux-oriented multipart command lines in the GUI, statements like "cd
> >>> c:foo; bar.exe; baz.exe" (we just swap "run_in" for "cd" on the windows
> >>> installation).
> >>>
> >>> Anyway, that's what it's for - why it doesn't work for you is a
> mystery.
> >>> Perhaps it's a path issue: how does the command line
> >>> c:\Inetpub\tpp-bin\run_in c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
> >>> c:\Inetpub\tpp-bin\tandem
> >>>
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
> >>>
> >>> work for you (that is, with full path to run_in specified)?
> >>>
> >>> On Wed, Mar 10, 2010 at 1:21 PM, Lik Wee Lee <[email protected]>
> >>> wrote:
> >>>>
> >>>> Hi,
> >>>>
> >>>> When I tried to do a xtandem search in the TPP petunia interface,
> >>>> I encountered the problem:
> >>>>
> >>>> # Commands for session TYBEEDEHS on Wed Mar 10 13:13:38 2010
> >>>> # BEGIN COMMAND BLOCK
> >>>> ###### BEGIN Command Execution ######
> >>>>
> >>>> [Wed Mar 10 13:13:38 2010] EXECUTING: run_in
> >>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem; c:\Inetpub\tpp-bin\tandem
> >>>>
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
> >>>> OUTPUT:
> >>>>
> >>>> command "c:\Inetpub\tpp-bin\tandem
> >>>>
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params"
> >>>> failed: Unknown error
> >>>>
> >>>>
> >>>>
> >>>>
> >>>> END OUTPUT
> >>>> RETURN CODE:65280
> >>>> ###### End Command Execution ######
> >>>> # All finished at Wed Mar 10 13:13:38 2010
> >>>> # END COMMAND BLOCK
> >>>>
> >>>> Does anyone have any ideas why this occur?
> >>>> However, the search was performed successfully if I did it by command
> >>>> line:
> >>>>
> >>>> c:\Inetpub\tpp-bin\tandem
> >>>>
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
> >>>>
> >>>> If I try
> >>>>
> >>>> run_in c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
> >>>> c:\Inetpub\tpp-bin\tandem
> >>>>
> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
> >>>>
> >>>> it says command failed: Unknown error.
> >>>>
> >>>> I have ActivePerl 5.8.9 build 827 and TPP version 4.3.1 installed on
> >>>> Windows XP SP3.
> >>>>
> >>>> Thanks,
> >>>> Lik Wee
> >>>>
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