Nope. I installed it recently and it complained about missing perl so I
downloaded 5.10 and installed it successfully.
But when I ran into problems, I thought it might be due to the perl
version, so I uninstall Perl 5.10.1 and TPP and then reinstall Perl 5.8.9
and TPP.

Lik Wee

On Wed, Mar 10, 2010 at 4:08 PM, Brian Pratt <[email protected]>wrote:

> Did you have a working TPP installation before?
>
> On Wed, Mar 10, 2010 at 3:54 PM, Lik Wee Lee <[email protected]>wrote:
>
>> Hi Brian,
>>
>>  On Wed, Mar 10, 2010 at 3:34 PM, Brian Pratt 
>> <[email protected]>wrote:
>>
>>> I think the fact that run_in doesn't work indicates some kind of system
>>> level problem that's going to make everything else flaky.  Perl shouldn't be
>>> an issue, at least at this point.
>>>
>>> So "c:\inetpub\tpp-bin\run_in c:\; dir" doesn't work for you?
>>>
>>
>> I still get  command "dir" failed: Unknown error
>>
>>>
>>> What do you see when you type this into your browser address bar?
>>> http://localhost/tpp-bin/check_env.pl
>>>
>>>
>>
>> SCRIPT_NAME = /tpp-bin/check_env.pl
>> SERVER_NAME = localhost
>> HTTP_ACCEPT_ENCODING = gzip,deflate
>> HTTP_CONNECTION = keep-alive
>> REQUEST_METHOD = GET
>> SYSTEMROOT = C:\WINDOWS
>> HTTP_ACCEPT =
>> text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8
>> SCRIPT_FILENAME = C:/Inetpub/tpp-bin/check_env.pl
>> COMSPEC = C:\WINDOWS\system32\cmd.exe
>> SERVER_SOFTWARE = Apache/2.2.8 (Win32)
>> HTTP_ACCEPT_CHARSET = ISO-8859-1,utf-8;q=0.7,*;q=0.7
>> WINDIR = C:\WINDOWS
>> QUERY_STRING =
>> REMOTE_PORT = 3227
>> PATHEXT = .COM;.EXE;.BAT;.CMD;.VBS;.VBE;.JS;.JSE;.WSF;.WSH
>> HTTP_USER_AGENT = Mozilla/5.0 (Windows; U; Windows NT 5.1; en-US;
>> rv:1.9.0.18) Gecko/2010020220 Firefox/3.0.18 (.NET CLR 3.5.30729)
>> SERVER_PORT = 80
>> SERVER_SIGNATURE =
>> HTTP_ACCEPT_LANGUAGE = en-us,en;q=0.5
>> HTTP_COOKIE = TPPSession=TYBEEDEHS:guest:249069786675ffea98006f8c1b444fa1
>> REMOTE_ADDR = 127.0.0.1
>> WEBSERVER_ROOT = c:\Inetpub\wwwroot;c:\Inetpub\wwwroot
>> HTTP_KEEP_ALIVE = 300
>> SERVER_PROTOCOL = HTTP/1.1
>> PATH = C:\Inetpub\tpp-bin;C:\Xcalibur\system\programs;C:\Program
>> Files\Thermo\Foundation;C:\Perl\site\bin;C:\Perl\bin;C:\WINDOWS\system32;C:\WINDOWS;C:\WINDOWS\System32\Wbem;C:\Program
>> Files\Common Files\Adaptec Shared\System;C:\Program Files\Analyst\bin
>> REQUEST_URI = /tpp-bin/check_env.pl
>> GATEWAY_INTERFACE = CGI/1.1
>> SERVER_ADDR = 127.0.0.1
>> DOCUMENT_ROOT = C:/Program Files/Apache Software
>> Foundation/Apache2.2/htdocs
>> HTTP_HOST = localhost
>>
>> Thanks for your help,
>> Lik Wee
>>
>>
>>>   It should give you a bunch of info including the PATH setting for your
>>> webserver.
>>>
>>>   On Wed, Mar 10, 2010 at 2:47 PM, Lik Wee Lee 
>>> <[email protected]>wrote:
>>>
>>>>  Hi Jimmy,
>>>>
>>>> Yes, I also checked the .tandem file there were peptides with low expect
>>>> score.
>>>> I also looked at the .pep.xml file and checked that the scans,
>>>> hyperscore,
>>>> nextscore, bscore, ... matched the .tandem file.
>>>>
>>>> I am puzzled why the run_in doesn't work and wondering if this is
>>>> affecting
>>>> the xinteract command as well. any ideas?
>>>>
>>>> Lik Wee
>>>>
>>>>
>>>> On Wed, Mar 10, 2010 at 2:20 PM, Jimmy Eng <[email protected]> wrote:
>>>>
>>>>> I suggest you start debugging the problem one step at a time.
>>>>> First confirm that your Tandem search actually ran by looking at
>>>>> contents of the .tandem file.
>>>>> Next, check contents of tandem.pep.xml.
>>>>> Do both of these files look like they have peptide IDs in them?
>>>>>
>>>>>
>>>>>
>>>>> On Wed, Mar 10, 2010 at 2:04 PM, Lik Wee Lee <[email protected]>
>>>>> wrote:
>>>>> > Furthermore, I also did:
>>>>> > C:\Inetpub\wwwroot\ISB\data\17mix>c:\Inetpub\tpp-bin\Tandem2XML
>>>>> > c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem
>>>>> >
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>> >
>>>>> > but if I tried to browse file in petunia and click on [PepXML],
>>>>> > it opens a new window:
>>>>> >
>>>>> http://localhost/tpp-bin/PepXMLViewer.cgi?xmlFileName=c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>> >
>>>>> > but with the message:
>>>>> >
>>>>> > error:
>>>>> > can't open html
>>>>> >
>>>>> templatec:/Inetpub/wwwroot;c:/Inetpub/wwwroot/ISB/html/PepXMLViewer.html
>>>>> >
>>>>> > I also had problem with xinteract:
>>>>> >
>>>>> > C:\Inetpub\wwwroot\ISB\data\17mix\tandem>c:\Inetpub\tpp-bin\xinteract
>>>>> > -Ninteract.pep.xml -p0.05 -l7 -O
>>>>> >
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.pep.xml
>>>>> >
>>>>> > c:\Inetpub\tpp-bin\xinteract (TPP v4.3 JETSTREAM rev 1, Build
>>>>> 200909091257
>>>>> > (MinGW))
>>>>> >
>>>>> > running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tand
>>>>> > em.pep.xml" -L"7""
>>>>> >
>>>>> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
>>>>> > m.pep.xml" -L"7"" failed: Unknown error
>>>>> >
>>>>> > command "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml"
>>>>> > "c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tande
>>>>> > m.pep.xml" -L"7"" exited with non-zero exit code: -1
>>>>> > QUIT - the job is incomplete
>>>>> >
>>>>> >
>>>>> >
>>>>> > Is this an installation issue? Any ideas?
>>>>> >
>>>>> > Thanks,
>>>>> > Lik Wee
>>>>> >
>>>>> > On Wed, Mar 10, 2010 at 1:53 PM, Lik Wee Lee <
>>>>> [email protected]>
>>>>> > wrote:
>>>>> >>
>>>>> >> Hi Brian,
>>>>> >>
>>>>> >> The full path still gives command "..." failed: unknown error.
>>>>> >>
>>>>> >> I tried "run_in c:" and didn't get any output.
>>>>> >>
>>>>> >> But if I try "run_in c:\; dir", I get:
>>>>> >> command "dir" failed: Unknown error.
>>>>> >>
>>>>> >> Could it be I previously had installed Perl 5.10? I uninstalled it
>>>>> >> and then installed Perl 5.8.9 followed by tpp 4.3.1.
>>>>> >>
>>>>> >> Lik Wee
>>>>> >>
>>>>> >> On Wed, Mar 10, 2010 at 1:34 PM, Brian Pratt <
>>>>> [email protected]>
>>>>> >> wrote:
>>>>> >>>
>>>>> >>> "run_in" is just a little program that runs one or more commands in
>>>>> the
>>>>> >>> indicated directory.  For example "run_in c:\foo; bar.exe; baz.exe"
>>>>> performs
>>>>> >>> "cd c:\foo" then runs "bar.exe" then "baz.exe".  It exists to help
>>>>> with
>>>>> >>> linux-oriented multipart command lines in the GUI, statements like
>>>>> "cd
>>>>> >>> c:foo; bar.exe; baz.exe" (we just swap "run_in" for "cd" on the
>>>>> windows
>>>>> >>> installation).
>>>>> >>>
>>>>> >>> Anyway, that's what it's for - why it doesn't work for you is a
>>>>> mystery.
>>>>> >>> Perhaps it's a path issue: how does the command line
>>>>> >>> c:\Inetpub\tpp-bin\run_in c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>> >>> c:\Inetpub\tpp-bin\tandem
>>>>> >>>
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>> >>>
>>>>> >>> work for you (that is, with full path to run_in specified)?
>>>>> >>>
>>>>> >>> On Wed, Mar 10, 2010 at 1:21 PM, Lik Wee Lee <
>>>>> [email protected]>
>>>>> >>> wrote:
>>>>> >>>>
>>>>> >>>> Hi,
>>>>> >>>>
>>>>> >>>> When I tried to do a xtandem search in the TPP petunia interface,
>>>>> >>>> I encountered the problem:
>>>>> >>>>
>>>>> >>>> # Commands for session TYBEEDEHS on Wed Mar 10 13:13:38 2010
>>>>> >>>> # BEGIN COMMAND BLOCK
>>>>> >>>> ###### BEGIN Command Execution ######
>>>>> >>>>
>>>>> >>>> [Wed Mar 10 13:13:38 2010] EXECUTING: run_in
>>>>> >>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>> c:\Inetpub\tpp-bin\tandem
>>>>> >>>>
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>> >>>> OUTPUT:
>>>>> >>>>
>>>>> >>>> command "c:\Inetpub\tpp-bin\tandem
>>>>> >>>>
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params"
>>>>> >>>> failed: Unknown error
>>>>> >>>>
>>>>> >>>>
>>>>> >>>>
>>>>> >>>>
>>>>> >>>> END OUTPUT
>>>>> >>>> RETURN CODE:65280
>>>>> >>>> ###### End Command Execution ######
>>>>> >>>> # All finished at Wed Mar 10 13:13:38 2010
>>>>> >>>> # END COMMAND BLOCK
>>>>> >>>>
>>>>> >>>> Does anyone have any ideas why this occur?
>>>>> >>>> However, the search was performed successfully if I did it by
>>>>> command
>>>>> >>>> line:
>>>>> >>>>
>>>>> >>>> c:\Inetpub\tpp-bin\tandem
>>>>> >>>>
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>> >>>>
>>>>> >>>> If I try
>>>>> >>>>
>>>>> >>>> run_in c:/Inetpub/wwwroot/ISB/data/17mix/tandem;
>>>>> >>>> c:\Inetpub\tpp-bin\tandem
>>>>> >>>>
>>>>> c:/Inetpub/wwwroot/ISB/data/17mix/tandem/OR20091211_18mix_01.tandem.params
>>>>> >>>>
>>>>> >>>> it says command failed: Unknown error.
>>>>> >>>>
>>>>> >>>> I have ActivePerl 5.8.9 build 827 and TPP version 4.3.1 installed
>>>>> on
>>>>> >>>> Windows XP SP3.
>>>>> >>>>
>>>>> >>>> Thanks,
>>>>> >>>> Lik Wee
>>>>> >>>>
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