Try renaming the mzXMl file to "F030382.mzXML", maybe?

On Mon, Jun 28, 2010 at 4:37 PM, Jing Wang <[email protected]> wrote:

> Hi Brian,
>
> I ran the Mascot search again with "trypsin" as enzyme, instead of
> tryspin/P. The .dat file was able to convert to .pep.xml file successfully
> (cool!). Well, there is a warning at the end of the command lines, and I
> don't know how important this is.
>
> ".......
>
> 333.   opening 334spectrum.0000.0000.3.out
>
>
>
>  warning: cannot open "c:/Inetpub/wwwroot/ISB/data/SSM411/F030382.mzXML"
> for reading MS instrument info.
>
> *Command Successful"*
>
> When I ran "Analyze Peptides" for the next step, It failed.  It seemed
> can't find .mzXML file (MS data?). There is the mzXML file in the same
> folder.
>
>
> see following error message:
>
> # Commands for session NYDW4ZIZ7 on Mon Jun 28 16:24:38 2010
>
> # BEGIN COMMAND BLOCK
>
> ###### BEGIN Command Execution ######
>
> [Mon Jun 28 16:24:38 2010] EXECUTING: run_in 
> c:/Inetpub/wwwroot/ISB/data/SSM411; c:\Inetpub\tpp-bin\xinteract  
> -NSSM411.pep.xml -p0.05 -l1 -Oi -X-m1.0-nC,9.0 -A-lC-r0.5-mC9.0 
> c:/Inetpub/wwwroot/ISB/data/SSM411/F030382.pep.xml
>
> OUTPUT:
>
>
>
> c:\Inetpub\tpp-bin\xinteract (TPP v4.3 JETSTREAM rev 1, Build 200909091257 
> (MinGW))
>
>
>
> running: "C:/Inetpub/tpp-bin/InteractParser "SSM411.pep.xml" 
> "c:/Inetpub/wwwroot/ISB/data/SSM411/F030382.pep.xml" -L"1""
>
>  file 1: c:/Inetpub/wwwroot/ISB/data/SSM411/F030382.pep.xml
>
>  processed altogether 238 results
>
>
>
>  results written to file c:/Inetpub/wwwroot/ISB/data/SSM411/SSM411.pep.xml
>
>
>  direct your browser to http://localhost/ISB/data/SSM411/SSM411.pep.shtml
>
>
>
> command completed in 0 sec
>
>
>
> running: "C:/Inetpub/tpp-bin/PeptideProphetParser "SSM411.pep.xml" 
> MINPROB=0.05 ICAT"
>
>  (MASCOT) (icat)
>
> results for charge 1: 0 id tot and 0 adj scores
>
> results for charge 2: 189 id tot and 55 adj scores
>
> results for charge 2: 21.2543 adj_ion_mean and 25.4733 adj_ion_hom mean 
> 23.7547id mean0.908354 correlation (r)
>
> 2+ ion - id = 0.988351*(ion - hom) + -3.92233 with error = 4.05281
>
> mean ion - id: 21.2543, mean ion - hom: 25.4733
>
> results for charge 3: 49 id tot and 16 adj scores
>
> results for charge 4: 0 id tot and 0 adj scores
>
> results for charge 5: 0 id tot and 0 adj scores
>
> results for charge 6: 0 id tot and 0 adj scores
>
> results for charge 6: -0 adj_ion_mean and -0 adj_ion_hom mean 0id meannan 
> correlation (r)
>
> results for charge 7: 0 id tot and 0 adj scores
>
> init with MASCOT trypsin
>
> MS Instrument info: Manufacturer: UNKNOWN, Model: UNKNOWN, Ionization: 
> UNKNOWN, Analyzer: UNKNOWN, Detector: UNKNOWN
>
>
>
>  PeptideProphet  (TPP v4.3 JETSTREAM rev 1, Build 200909091257 (MinGW)) 
> akel...@isb
>
>  read in 0 1+, 188 2+, 49 3+, 0 4+, 0 5+, 0 6+, and 0 7+ spectra.
>
> Initialising statistical models ...
>
> Iterations: .........10.........20....
>
> model complete after 25 iterations
>
> command completed in 0 sec
>
>
>
> running: "C:/Inetpub/tpp-bin/ProphetModels.pl -i SSM411.pep.xml"
>
> Analyzing SSM411.pep.xml ...
>
> Parsing search results "c:/Inetpub/wwwroot/ISB/data/SSM411/F030382 
> (MASCOT)"...
>
>   => Total of 154 hits.
>
> command completed in 1 sec
>
>
>
> running: "C:/Inetpub/tpp-bin/XPressPeptideParser "SSM411.pep.xml" -m1.0 
> -nC,9.0"
>
> WARNING: Found more than one variable mod on 'C'.
>
> XPRESS error - cannot open file from basename 
> c:/Inetpub/wwwroot/ISB/data/SSM411/F030382, will try to derive from scan names
>
> scan-derived scan file c:/Inetpub/wwwroot/ISB/data/SSM411/.mzXML (from ) not 
> found, cannot proceed...
>
>
>
> command "C:/Inetpub/tpp-bin/XPressPeptideParser "SSM411.pep.xml" -m1.0 
> -nC,9.0" failed: Operation not permitted
>
>
>
> command "C:/Inetpub/tpp-bin/XPressPeptideParser "SSM411.pep.xml" -m1.0 
> -nC,9.0" exited with non-zero exit code: 1
>
> QUIT - the job is incomplete
>
>
>
> command "c:\Inetpub\tpp-bin\xinteract -NSSM411.pep.xml -p0.05 -l1 -Oi 
> -X-m1.0-nC,9.0 -A-lC-r0.5-mC9.0 
> c:/Inetpub/wwwroot/ISB/data/SSM411/F030382.pep.xml" failed: Operation not 
> permitted
>
> END OUTPUT
>
> RETURN CODE:256
>
> ###### End Command Execution ######
>
> # All finished at Mon Jun 28 16:24:39 2010
>
> # END COMMAND BLOCK
>
>
>
> Any suggestion for fixing this?
>
> Thanks in advance
>
> Jing
>
>
>
> On Thu, Jun 24, 2010 at 8:06 AM, Brian Pratt <[email protected]>wrote:
>
>> Not everyone has read access to the ISB's FTP server (including me), which
>> is why I said "upload your new mascot result file to the files area at
>> http://groups.google.com/group/spctools-discuss?hl=en. "
>>
>> Anyway, there are two problems:
>> 1) 'error: enzyme in search constraint "Trypsin/P" is not recognized'
>> 2) the above message doesn't appear by default and the program fails
>> silently
>>
>> I'll check in a fix for the second problem.
>>
>
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