I suspect you're correct, but i'm surprised, too. Actually, it doesn't say
that the mzXml is invalid (as I originally posted), only unsupported. The
error message: "The specified file is not a supported mzXml format".

When launching a Mascot search, the message is also vague: "Exception of
type 'System.OutOfMemoryException' was thrown".

I have an old msXML2Other lying around, which gives "Peak data exceeds peak
count." I wondered if it's the same root problem.

Thanks. I should contact Thermo, you're right.

Jeff


On Tue, Oct 19, 2010 at 2:21 PM, Matthew Chambers <[email protected]
> wrote:

>  I speculate that Proteome Discoverer was written for an older version of
> the mzXML schema and some of the newer attributes and/or elements are giving
> it trouble. But if that's the case it must be doing some schematic
> validation like Mascot does because I don't recall any attributes and/or
> elements that have been /removed/ since 2.0. Have you asked a Thermo
> representative? Is there a specific error message?
>
> -Matt
>
>
>
> On 10/19/2010 1:07 PM, Jeffrey Milloy wrote:
>
>> Hi there again
>>
>> I am using Thermo's Proteome Discover to do some testing with SEQUEST
>> searches. You can input a RAW file or an mzXML for the search, and
>> Discoverer handles the rest.
>>
>> mzXMLs produced with ReAdW 4.0.2 work just fine.
>> mzXMLs produced with ReAdW 4.3.1 do *not* work.
>> mzXMLs produced with msconvert do *not* work.
>>
>> Discoverer says that they are invalid mzXML files and does not load
>> them. Any thoughts? Anyone else using ReAdW and Discoverer? Is this
>> more likely to be a problem with ReAdW/msconvert or with Discoverer?
>>
>> MzXML2Search seems to be able to handle the different mzXMLs just
>> fine.
>>
>>
>> Jeff
>>
>>
>> TPP 4.4 (winxp install)
>> Thermo Proteome Discoverer 1.2
>>
>>
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