How did it process it as Sequest if the search_engine attribute still says 
"Crux"?

-Matt


On 2/2/2011 5:30 AM, Andreas Quandt wrote:
hey jimmy,

thanks for the reply!
i tried to follow your advice wtih modifying the pepxml produced by crux.
however it seems i am not pulling the right strings.

when having a crux header like this:

<?xml version="1.0" encoding="UTF-8"?>
<?xml-stylesheet type="text/xsl" href="">
<msms_pipeline_analysis date="Tue Feb  1 23:30:51 2011
" xmlns="" xmlns:xsi="" xsi:schemaLocation="" summary_xml="">
<msms_run_summary 
base_name="/cluster/scratch/malars/mzxml/plasmaprot/B08-02057.mzXML"
msManufacturer="NA" msModel="NA" msIonization="NA" msAnalyzer="NA" 
msDectector="NA"
raw_data_type="NA" raw_data="NA" >
<sample_enzyme name="trypsin">
</sample_enzyme>
<search_summary 
base_name="/cluster/scratch/malars/mzxml/plasmaprot/B08-02057.mzXML"
search_engine="Crux" precursor_mass_type="average" 
fragment_mass_type="monoisotopic"
out_data_type="NA" out_data="NA" search_id="1" >
<search_database
local_path="/cluster/scratch/malars/databases/AE004092_sp_9606.idx/AE004092_sp_9606-binary-fasta"
type="AA" />
<enzymatic_search_constraint enzyme="trypsin" max_num_internal_cleavages="0" 
min_number_termini="2"/>
<aminoacid_modification aminoacid="C" mass="160.160263" massdiff="57.021464" 
variable="N" />
<parameter name="fragment-mass" value="mono"/>

i tried various modifications of the msms_run_summary and the search_summary 
tags but i always get
the same error:

read no data

[quandtan@brutus2 crux-output]$ xinteract -dDECOY_ -OAdlIw search.mod.pep.xml

running: "/cluster/apps/tpp/4.4.1/bin/PeptideProphetParser 'interact.pep.xml' 
DECOY=DECOY_ ACCMASS
DECOYPROBS LEAVE PI INSTRWARN"
using Accurate Mass Bins
using pI
Using no error on different instrument types.
Using Decoy Label "DECOY_".
Decoy Probabilities will be reported.
  (SEQUEST) (leaving deltacn* entries)
adding Accurate Mass mixture distr
adding pI mixture distr
init with SEQUEST trypsin
MS Instrument info: Manufacturer: NA, Model: NA, Ionization: NA, Analyzer: 
UNKNOWN, Detector: UNKNOWN

  PeptideProphet  (TPP v4.4 VUVUZELA rev 1, Build 201102011840 (linux)) 
AKeller@ISB
  read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, and 0 7+ spectra.
  read in no data

command "/cluster/apps/tpp/4.4.1/bin/PeptideProphetParser 'interact.pep.xml' 
DECOY=DECOY_ ACCMASS
DECOYPROBS LEAVE PI INSTRWARN" exited with non-zero exit code: 256


can you or probably david point me to what i am doing wrong?

cheers + thanks:-)
andreas

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