It did not end up for me. I am using comet (not tandem) on a windows 
machine and sometimes I got "*file not found:* not created or deleted?" I 
have reduced the filename to just a number. 
My output files are always created in the parameter folder. Is there a 
possibility to use a differnt folder for it ?
I am using TPP v4.8.0 PHILAE, Build 201411201551-6764 (mingw-i686).
Norbert

On Monday, July 22, 2013 11:18:19 PM UTC+2, Kierstin wrote:
>
> It ended up being a parameters issue.  Now it's working.  Thanks so much!  
>
> On Monday, July 22, 2013 4:39:50 PM UTC-4, [email protected] 
> wrote:
>>
>> Kierstin,
>>
>> You might want to take a 2nd look at what parameters you are also using 
>> for X!Tandem.  I find it pretty useful to use the API documentation 
>> <http://www.thegpm.org/tandem/api/index.html> as a guide.  What platform 
>> are you running TPP on, Windows? and what version of TPP are you using?
>>
>> -Joe
>>
>>
>>
>> On Mon, Jul 22, 2013 at 11:35 AM, Kierstin <[email protected]> wrote:
>>
>>> Thanks Joe!
>>>
>>> I checked out my spectrum in Pep3D and it looks fine!  For the database 
>>> input, I'm using the FASTA file, I'm just using the standard Human 
>>> database, and for the parameters, the default tandem parameters file.  I've 
>>> gone through it and don't see any special characters.  If you have any 
>>> other suggestions, I'll definitely try them!  
>>>
>>> Thanks,
>>>
>>> Kierstin
>>>
>>>
>>> On Monday, July 22, 2013 12:23:28 PM UTC-4, [email protected] 
>>> wrote:
>>>
>>>> Kierstin,
>>>>
>>>> Try checking your input to X!Tandem.  Make sure the database doesn't 
>>>> have any "bad" sequences in it. Often times special characters sneak into 
>>>> the file and can cause X!Tandem to crash.  Also take a look at your 
>>>> spectrum -- can you see the input file in Pep3D?
>>>>
>>>> -Joe
>>>>
>>>>
>>>> On Mon, Jul 22, 2013 at 9:20 AM, Kierstin <[email protected]> 
>>>> wrote:
>>>>
>>>>> Hi!
>>>>>
>>>>> Thanks for the suggestion!  I removed all of the spaces and alternate 
>>>>> characters and am still getting the same error messages.  Is there 
>>>>> anything 
>>>>> else I should try?  Should I recheck my parameters file?
>>>>>
>>>>> Thanks!
>>>>>
>>>>> Kierstin
>>>>>
>>>>>
>>>>>    - c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem (*file 
>>>>>    not found:* not created or deleted?)
>>>>>    - c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem.pep.xml 
>>>>>    (*file not found:* not created or deleted?) 
>>>>>
>>>>>  
>>>>>
>>>>>   Command 1 *[Mon Jul 22 12:11:18 2013] *       [ Show / Hide ] 
>>>>>
>>>>>  run_in c:/Inetpub/wwwroot/ISB/data/Tandem; c:\Inetpub\tpp-bin\tandem 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem.params 
>>>>>
>>>>> ------------------------------
>>>>>
>>>>> X! TANDEM 2010.10.01.1 (LabKey, Insilicos and ISB)
>>>>>
>>>>> Loading spectra .
>>>>> This application has requested the Runtime to terminate it in an unusual 
>>>>> way.
>>>>> Please contact the application's support team for more information.
>>>>>
>>>>> command "c:\Inetpub\tpp-bin\tandem 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem.params" 
>>>>> failed: No such process
>>>>>
>>>>> *Command FAILED* 
>>>>>
>>>>>
>>>>>   Command 2 *[Mon Jul 22 12:11:19 2013] *       [ Show / Hide ] 
>>>>>
>>>>>  run_in c:/Inetpub/wwwroot/ISB/data/Tandem; c:\Inetpub\tpp-bin\Tandem2XML 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem.pep.xml 
>>>>>
>>>>> ------------------------------
>>>>>
>>>>> Failed to open input file 
>>>>> 'c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem'.
>>>>>
>>>>> command "c:\Inetpub\tpp-bin\Tandem2XML 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem 
>>>>> c:/Inetpub/wwwroot/ISB/data/Tandem/MS13668QE_sample2.tandem.pep.xml" 
>>>>> failed: Operation not permitted
>>>>>
>>>>> *Command FAILED* 
>>>>>
>>>>> On Wednesday, July 17, 2013 7:28:22 PM UTC-4, Jimmy Eng wrote:
>>>>>
>>>>>> Along these lines, everyone should simply avoid any symbols in 
>>>>>> directory and file names.  There are some character symbols that are OK 
>>>>>> (I 
>>>>>> tell folks to use dash '-' and underscore '_' only besides letters and 
>>>>>> numbers) but it's best to avoid them all if you don't know which ones 
>>>>>> will 
>>>>>> work.
>>>>>>
>>>>>>
>>>>>> On Wed, Jul 17, 2013 at 3:28 PM, Brian Hampton <[email protected]> 
>>>>>> wrote:
>>>>>>
>>>>>>> Well, I could be wrong, but that space in the directory name is 
>>>>>>> probably the culprit.  I would rename the directory .../data/X! Tandem 
>>>>>>> to 
>>>>>>> something without a space in it.  Just call it .../data/tandem instead. 
>>>>>>>  
>>>>>>>
>>>>>>> Cheers,
>>>>>>>
>>>>>>> Brian
>>>>>>>
>>>>>>> Brian Hampton
>>>>>>> Protein Analysis Lab
>>>>>>> Center for Vascular and Inflammatory Diseases
>>>>>>> University of Maryland School of Medicine
>>>>>>> 800 West Baltimore Street Rm 307
>>>>>>> Baltimore  MD  21201
>>>>>>> V: 410-706-8207
>>>>>>> F: 410-706-8234
>>>>>>>  
>>>>>>>
>>>>>>> On Wed, Jul 17, 2013 at 5:24 PM, Kierstin Schmidt <
>>>>>>> [email protected]> wrote:
>>>>>>>
>>>>>>>>  Hi!  
>>>>>>>> I am a new user of TPP.  I am trying to load my mzXML files to be 
>>>>>>>> searched by X! Tandem, and I keep getting the following errors.  If 
>>>>>>>> anyone 
>>>>>>>> has advice, it would be greatly appreciated!
>>>>>>>>
>>>>>>>> Thanks!
>>>>>>>>
>>>>>>>> Kierstin
>>>>>>>>
>>>>>>>>
>>>>>>>>  "c:/Inetpub/wwwroot/ISB/data/X! Tandem/MS138QE_sample2.tandem.pep.xml 
>>>>>>>> (*file not found:* not created or deleted?)
>>>>>>>>
>>>>>>>> Followed by
>>>>>>>>
>>>>>>>>  run_in c:/Inetpub/wwwroot/ISB/data/X!Tandem; 
>>>>>>>> c:\Inetpub\tpp-bin\tandem c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem.params 
>>>>>>>>
>>>>>>>> ------------------------------
>>>>>>>>
>>>>>>>> X! TANDEM 2010.10.01.1 (LabKey, Insilicos and ISB)
>>>>>>>>
>>>>>>>> Loading spectra .
>>>>>>>> Failed to open: "c:/Inetpub/wwwroot/ISB/data/X!Tandem"
>>>>>>>> The input parameter file "c:/Inetpub/wwwroot/ISB/data/X!Tandem" could 
>>>>>>>> not be located.
>>>>>>>> Check the file path name and try again.
>>>>>>>>
>>>>>>>>
>>>>>>>> An error was detected while loading the input parameters.
>>>>>>>> Please follow the advice above or contact a GPM administrator to help 
>>>>>>>> you.
>>>>>>>> command "c:\Inetpub\tpp-bin\tandem c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem.params" failed: Unknown error
>>>>>>>>
>>>>>>>> *Command FAILED* 
>>>>>>>>
>>>>>>>>
>>>>>>>>   Command 2 *[Wed Jul 17 17:11:38 2013] *       [ Show / Hide ] 
>>>>>>>>
>>>>>>>>  run_in c:/Inetpub/wwwroot/ISB/data/X!Tandem; 
>>>>>>>> c:\Inetpub\tpp-bin\Tandem2XML c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem.pep.xml 
>>>>>>>>
>>>>>>>> ------------------------------
>>>>>>>>
>>>>>>>>  c:\Inetpub\tpp-bin\Tandem2XML(TPP v4.5 RAPTURE rev 2, Build 
>>>>>>>> 201202031108 (MinGW))
>>>>>>>> Usage: c:\Inetpub\tpp-bin\Tandem2XML <input-file> [<output-file>]
>>>>>>>>
>>>>>>>> command "c:\Inetpub\tpp-bin\Tandem2XML c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem c:/Inetpub/wwwroot/ISB/data/X! 
>>>>>>>> Tandem/MS138QE_sample2.tandem.pep.xml" failed: Operation not permitted
>>>>>>>>
>>>>>>>> *Command FAILED* 
>>>>>>>>
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