Hi,

2012/10/31 Anu Nagarajan <[email protected]>:
> Hi,
>
> I am trying to run the thermodynamic force using csg_inverse. I have the
> settings.xml file with appropriate options for my system. But, when I try to
> run TF, I get about 2-3 iterations after which the temperature gets really
> high and the system becomes unstable. I have the latest version (1.2.3) of
> votca. I computed the prefactor based on the compressibility of the
> atomistic region.  According to the tutorial and the paper, I have set the
> TF range to be d(skin)+d(at)+d(hy)+d(skin) where d(skin) is right now half
> the cutoff distance. The entire molecule is one charge group and I have 12
> atoms plus virtual site.  Do I have to change any values in the settings.xml
> file? Is there anything I might be missing?
The parameters will depend on the system you study.
Here are some things you could try:
- increase adress_ex_forcecap in the mdp file
- increase the spline grid (spline_start, spline_end in
cg.non-bonded.inverse.tf) in setting.xml
- add a cg_prefactor in  cg.non-bonded.inverse.tf, which is based on
the compressibility of the cg model
- scale the update (add postupd task scale) by something < 1

Sebastian, please add stuff if I have missed something.

Christoph
>
> I appreciate any help in this matter!
>
> Thanks!
> Anu
>
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--
Christoph Junghans
Web: http://www.compphys.de

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