Re: [NMusers] Absorption

of the curves should provide some useful clues about what is going on. Best regards Justin Justin Wilkins Novartis Pharma AG PH346, MODELING SIMULATION CHBS, WSJ-027.1.084 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41 61 324 6549 Fax: +41 61 324 3039 Mobile: +41 76 561

Re: [NMusers] Automated way to extract NM output

Dear all, A comment on Xpose - no, support for multiple $PROBLEM statements is not present in the current version (4.0PR6U1) - and this is not something planned for Census, either, come to that. By a show of hands, is this something people would like to see implemented? Best regards Justin

[NMusers] Census 1.0b2 released

get in touch. Finally, it's important to note that this release, while quite mature and stable, is still a beta, and is likely to contain (minor) bugs. If you find any, please let me know so they can be addressed in time for the imminent 1.0 release. Best regards -- Justin Wilkins

[NMusers] Census 1.0 released

any NONMEM output to which Windows has access to via drive mapping. Census is, and will remain, free software under the Mozilla Public License, version 1.1. Best Justin -- Justin Wilkins - Colmarerstrasse 31 4055 Basel Switzerland - Email

Re: [NMusers] Re: PharmPK Re: NMTRAN error

0.419 ... although it must be said that this data structure seems to create issues with PsN. Best Justin Justin Wilkins Senior Modeler Modeling Simulation (Pharmacology) CHBS, WSJ-027.6.076 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41 61 324 6549 Fax: +41 61 324 1246

Re: [NMusers] Census 1.1 beta released

for a Mac Os or linux version? Saludos, -- Dr. Carlos Hoyo Vadillo Sec. Ext. Farmacología Cinvestav Av. IPN 2508 San Pedro Zacatenco 07360 México DF Tel: +52-55-5061-3800 ext 5438 Cel. 55-385 22 888 citocr...@cinvestav.mx On May 17, 2009, at 6:10 PM, Justin Wilkins wrote

Re: [NMusers] Census 1.1 beta released

, -- Dr. Carlos Hoyo Vadillo Sec. Ext. Farmacología Cinvestav Av. IPN 2508 San Pedro Zacatenco 07360 México DF Tel: +52-55-5061-3800 ext 5438 Cel. 55-385 22 888 citocr...@cinvestav.mx On Jun 2, 2009, at 5:09 AM, Justin Wilkins wrote: Dear Carlos, In principle, porting

Re: [NMusers] time-dependent residual error models

Justin Justin Wilkins, PhD Senior Modeler Modeling Simulation (Pharmacology) CHBS, WSJ-027.6.076 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41 61 324 6549 Fax: +41 61 324 1246 Cell: +41 76 561 0949 Email : justin.wilk...@novartis.com Nick Holford n.holf

Re: [NMusers] Error message in Xpose 4

when plotting to a file? e.g. xp1 - xpose.data(1) pdf(file=indplots.pdf, width=10, height=10) ind.plots(xp1) dev.off() Best Justin Justin Wilkins, PhD Senior Modeler Modeling Simulation (Pharmacology) CHBS, WSJ-027.6.076 Novartis Pharma AG Lichtstrasse 35 CH-4056 Basel Switzerland Phone: +41

Re: [NMusers] NM7 and Census

, Why I can not Open .res files in Census? Carlos Hoyo. -- Justin Wilkins - Colmarerstrasse 31 4055 Basel Switzerland - Email: justin...@gmail.com Skype: kestrel_za2002 Mobile: +41 76 561 0949

[NMusers] Census 1.1 RC released

Dear all, Census 1.1 Release Candidate has been released. This version includes a number of enhancements: * A bug that affected the importing of $OMEGA BLOCK initial estimates under some circumstances has been corrected. * Full support for recent Xpose releases has been added. * A range of other

Re: [NMusers] Transit Compartment Model for PK with Multiple Doses

factor in the transit compartment equations (Sun YN, Jusko WJ. J Pharm Sci. 1998 Jun;87(6):732-7), but it seems to be fairly unstable in NONMEM. Can anyone comment/help? Thanks in advance, Matt -- Justin Wilkins - Colmarerstrasse 31 4055 Basel Switzerland

Re: [NMusers] is there a way to change fit to csv

? Kind Regards *Chandramouli Radhakrishnan* * * -- Justin Wilkins - Colmarerstrasse 31 4055 Basel Switzerland - Email: justin...@gmail.com Skype: kestrel_za2002 Mobile: +41 76 561 0949

[NMusers] Census 1.1 released...

Dear all, Census 1.1 has been released. This is a maintenance release, fixing all known issues, including a startup crash that affected some users, and setting the stage for the introduction of NONMEM 7 support. There are too many changes to go into here, but full details are available from the

[NMusers] Census: new release with NONMEM 7 support

is, and will remain, free software under the Mozilla Public License, version 1.1. Comments, criticisms, and suggestions are always welcome. Best regards Justin Wilkins

Re: [NMusers] Transit compartment model with multiple dose data

=IRES/W ... -- Justin Wilkins, PhD Exprimo NV Tel: +41 (0) 81 599 23 82 Mobile: +41 (0) 76 561 09 49 E-mail: justin.wilk

Re: [NMusers] Confidence intervals of PsN bootstrap output

software: www.winpopt.com -- Justin Wilkins, PhD Exprimo NV Tel:+41 (0) 81 599 23 82 Mobile: +41 (0) 76 561 09 49 E-mail: justin.wilk...@exprimo.com Web:www.exprimo.com This e-mail is confidential. It is also privileged or otherwise protected by work product immunity

Re: [NMusers] Installation of NM7.2 on OSX lion for dummies.

elektronische verzending van het bericht kunnen er geen rechten worden ontleend aan de informatie. -- Justin Wilkins, PhD Exprimo NV Tel:+41 (0) 81 599 23 82 Mobile: +41 (0) 76 561 09 49 E-mail: justin.wilk...@exprimo.com Web:www.exprimo.com This e-mail is confidential. It is also

Re: [NMusers] Memory problems with Xpose

allocation of 1535Mb: see help(memory.size) Error in print(parm.vs.cov(.cur.db)) : error in evaluating the argument 'x' in selecting a method for function 'print': Error: cannot allocate vector of size 171 Kb Can anybody offer a remedy? Thanks! Toufigh -- Justin Wilkins, PhD Exprimo

Re: [NMusers] xpose help

Dear Justus, Your best bet may be not to use the ind.plots function at all, and instead use standard lattice, e.g. library(xpose4) xp - xpose.data(1) ; load NM data x - xp@Data ; move the Xpose data somewhere more convenient xyplot(DV ~ TIME | factor(ID), data=subset(x,

[NMusers] Census 2 is released!

, and suggestions are welcome. If you would like to help with the development of Census 2, please contact me. Thanks and appreciation to my colleagues at Exprimo for being my alpha testers! Best regards Justin Wilkins This e-mail message has been scanned for Viruses

[NMusers] Census 2.01 is released

. If you would like to help with the development of Census 2, please contact me. Thanks and appreciation to my colleagues at Exprimo for beta testing! Best regards Justin Justin Wilkins, PhD Life Science Services - Exprimo Senior Consultant Phone: +41 81 599 2382 E-mail: justin.wilk

[NMusers] DDMoRe Community Groups have launched

Dear Modelers, On January 17th, we launched the DDMoRe Foundation Community Groups – Model Repository, Standards and Thoughtflow – to support standardization, knowledge and model sharing in pharmacometrics. We welcome any volunteers to join one or more of these community groups to work

[NMusers] ISoP Announces Reduced Membership Fees

tory and Career Center; and the opportunity to participate in ISoP as members or chairs of committees, officers, and/or Board members. Full details are available at http://www.go-isop.org/membership. -- Justin Wilkins for the ISoP Board of Directors

[NMusers] ISoP Request for Comments: Exposure-Response Analysis in Drug Development and Regulatory Decision Making

help, Al!), and ISoP Board member Jonathan French (jonath...@metrumrg.com). Please reach out to them if you have any questions! We look forward to hearing from you! Best regards, Justin Wilkins on behalf of ISoP

RE: [NMusers] OFV or Diagnostic Plot ?? Which one rules...

Justin — Justin Wilkins, PhD Occams Kirchnerstraße 22 59457 Werl Germany www.occams.com +49 2922 927 8843 justin.wilk...@occams.com<mailto:justin.wilk...@occams.com> linkedin.com/in/justinjwilkins<https://www.linkedin.com/in/justinjwilkins/> [cid:image001.png@01D2198E.CAACFA30] From

[NMusers] Vote: ISoP Board elections - polls close soon!

rincione, Stephen Duffull, Jonathan French, Siv Jonsson, CJ Musante, Yusuke Tanigawara, Heather Vezina, and Justin Wilkins. Members are entitled to vote for two candidates. Before voting, please carefully review each of the statements from our candidates so you can make an informed choice. Please

[NMusers] ISoP Tools & Resources Survey

tems biology, physiologically-based pharmacokinetics, and data programming. It will remain open until Monday 27 April 2020. Best regards Justin Wilkins Chair: Tools & Resources Working Group, ISoP International Society of Pharmacometrics 1200 Rt 22 East Su

RE: [NMusers] Assessment of elimination half life of mAb

Hi Bill, all, I do much the same thing - when there's nonlinearity happening, I've found it to be effective to plot concentration-time curves by doses and regimens of interest and mark the times at which the (median?) clinically-defined threshold for "washout" has been reached in each case. Of