Well said. I've seen three cases by now when switching to a homologue
from a different organism led to solving a structure (and way too many
cases when crystals just did not diffract, either at all or well
enough :).
On Tue, 2010-08-31 at 18:48 +0300, Tommi Kajander wrote:
> Or might be worth going back to the drawing board to design more
> constructs (and check them around the same conditions), thermostable
> homologs etc.. what about reductive methylation, anyone had luck
> with
> membrane proteins?
>
--
"I'd jump in myself, if I weren't so good at whistling."
Julian, King of Lemurs
