Yea, Parveen has actually asked about this here a year ago and I found this discussion quite useful indeed:
www.mail-archive.com/ccp4bb@jiscmail.ac.uk/msg11717.html and I think we all get tons of these crystals especially in conditions with PEGs. There are lots of things you can try and have been suggested, but I found this reference most helpful by far: "A general protocol for the crystallization of membrane proteins for X-ray structural investigation." http://www.ncbi.nlm.nih.gov/pubmed/19360018 (this is actually the paper in the link that Eric posted: http://kb.psi-structuralgenomics.org/update/2009/06/full/th_psisgkb.2009.25.html) Best, Matt On Tue, Aug 31, 2010 at 12:53 PM, Parveen Goyal <parveen...@gmail.com>wrote: > Hi, > > The picture looks like detergent crystals, specially DDM crystals. I have > same crystals in many conditions. > > With regards, > Parveen > -- -------------------------------------------------------------------------------------------- Matthew L.H. Chu, PhD Postdoctoral Scholar - Weis Lab Department of Structural Biology Fairchild D143, MC 5126 Stanford School of Medicine Stanford, CA 94305-5432 Lab: 650-724-3306 Alternative Email: matt...@stanford.edu --------------------------------------------------------------------------------------------