Wukovitz & Yeates (1995) Nature Struc. Biol. 2(12): 1062-1067
predicts that the most probable space group for macromolecular
crystallization is P -1 (P 1-bar). All you have to do to try it out is
synthesize the all-D enantiomer of your protein and get it to fold properly.
On 02/14/12 18:36, Prem Kaushal wrote:
Hi
We have a protein that crystallized in P21212 space group. We are
looking for some different crystal forms. We tried few things did not
work. Now we are thinking to mutate surface residues. Anybody aware of
any software which can predict the mutations that might help in
crystallizing protein in different space group, please inform me.
Thanks in advance
Prem
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All Things Serve the Beam
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David J. Schuller
modern man in a post-modern world
MacCHESS, Cornell University
[email protected]
