On 02/15/12 12:41, Jacob Keller wrote:
Are there any all-D proteins out there, of known structure or
otherwise? If so, do enantiomer-specific catalyses become inverted?

JPK

I looked a little harder, and at least one D-enantiomeric protein was an enzyme:

Total chemical synthesis of a D-enzyme: the enatiomers of HIV-1 protease show demonstration of reciprocal chiral substrate specificty R.C. deL. Milton, S.C.F. Milton, S.B.H. Kent (1992) Science 256(5062) 1445-1448.

I guess that answers your question.

--
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All Things Serve the Beam
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                               David J. Schuller
                               modern man in a post-modern world
                               MacCHESS, Cornell University
                               [email protected]

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