Steve Kent has published a few more (at least 1 other) since HIV... 3ODV http://www.rcsb.org/pdb/explore/explore.do?structureId=3ODV
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Pentelute, B.L., Mandal, K., Gates, Z.P., Sawaya, M.R., Yeates, T.O., Kent, S.B., Journal: (2010) Chem.Commun.(Camb.) 46: 8174-8176 _________________________________ Joel Tyndall, PhD Senior Lecturer in Medicinal Chemistry National School of Pharmacy University of Otago PO Box 56 Dunedin 9054 New Zealand Skype: jtyndall http://www.researcherid.com/rid/C-2803-2008 Pukeka Matua Te Kura Taiwhanga Putaiao Te Whare Wananga o Otago Pouaka Poutapeta 56 Otepoti 9054 Aotearoa Ph / Waea +64 3 4797293 Fax / Waeawhakaahua +64 3 4797034 -----Original Message----- From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of Jacob Keller Sent: Thursday, 16 February 2012 7:36 a.m. To: [email protected] Subject: Re: [ccp4bb] surface residue mutation Right on the money! JPK On Wed, Feb 15, 2012 at 12:28 PM, David Schuller <[email protected]> wrote: > On 02/15/12 12:41, Jacob Keller wrote: >>> >>> Are there any all-D proteins out there, of known structure or >>> otherwise? If so, do enantiomer-specific catalyses become inverted? >>> >>> JPK >>> > I looked a little harder, and at least one D-enantiomeric protein was > an > enzyme: > > Total chemical synthesis of a D-enzyme: the enatiomers of HIV-1 > protease show demonstration of reciprocal chiral substrate specificty > R.C. deL. Milton, S.C.F. Milton, S.B.H. Kent (1992) Science 256(5062) > 1445-1448. > > I guess that answers your question. > > > -- > ====================================================================== > = > All Things Serve the Beam > ====================================================================== > = > David J. Schuller > modern man in a post-modern world > MacCHESS, Cornell University > [email protected] -- ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program email: [email protected] *******************************************
