--- In [email protected], "sshine2412" <[EMAIL PROTECTED]> wrote:
> 
> Does anybody know how long Gleevec lasts?  It looks like most people 
> are still in remission 4 or 5 years after taking this medicine, but 
> I'm wondering if anyone knows about long term benefits (5-10+ 
> years).

_______________

Hi sshine, 

Gleevec has only been taken now for about 6 years by those in the 
earliest trials....I have been on Gleevec for 5 years (and still 
kicking!)

Part of the answer depends on the level of response that you get from 
Gleevec....ie, whether you have a cytogenetic response, get to CCR or 
PCRU. There are different relapse rate %s depending on your response 
to the drug. At CCR, the relaspse rate is 2% a year. 

Recently, Dr. Druker told me that he can now confidently tell a newly 
diagnosed patient that their CML will be a chronic disease, managed by 
drugs. If someone goes on Gleevec now and eventually relapses, there 
will be the other 2nd generation drugs available (probably BMS and 
AMN, now in trials). So, no long history with Gleevec but a good 
outlook.

Nancy C.  





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