just out of curiosity what dosage are you on.....my wife is going on 11 years with gleevec,but has always been on a low dosage.....200 mg a day......thank-you rob
________________________________ From: skink1100 <[email protected]> To: CMLHope <[email protected]> Sent: Monday, March 12, 2012 1:54 PM Subject: [CMLHope] loss of effectiveness of gleevec and sprycel I have had cml for nearly 10 years. For several years I was at the not detectable level in my pcr tests. Last year the gleevec seemed to no longer be as effective...and my doctor switched me to sprycel...about 4 months ago...my results continue to decline, although my blood looks ok. Has anyone had a similar experience...could it be a new mutation? Where does on go from here...getting worried. -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope

