Well the good thing about switching to sprycel was all my side effects
disapeared...muscle cramps, and diarhea mostly...definitely a mild
impact drug when it works.  I am going to get tested for
mutations...that could be the issue...

On Mar 12, 2:40 pm, lrc lrc <[email protected]> wrote:
> Don't worry.  Same thing happened to me.  Dr Talpaz likes Sprycel better
> because of less side affects.  I switch in June 2011 and I have no more
> cramps, diarrhea, up set stomach and many more.  Who is your doctor?
> On Mar 12, 2012 1:54 PM, "skink1100" <[email protected]> wrote:
>
>
>
>
>
>
>
> > I have had cml for nearly 10 years.  For several years I was at the
> > not detectable level in my pcr tests.  Last year the gleevec seemed to
> > no longer be as effective...and my doctor switched me to
> > sprycel...about 4 months ago...my results continue to decline,
> > although my blood looks ok.  Has anyone had a similar
> > experience...could it be a new mutation?  Where does on go from
> > here...getting worried.
>
> > --
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