My wife has been on Gleevec since we went to Detroit in phase three of 
testing. She takes 200 mg. daily.  My name is Don 
 
Don Donofrio




________________________________
From: robert goodrich <[email protected]>
To: "[email protected]" <[email protected]>
Sent: Mon, March 12, 2012 10:22:49 PM
Subject: Re: [CMLHope] loss of effectiveness of gleevec and sprycel


just out of curiosity what dosage are you on.....my wife is going on 11 years 
with gleevec,but has always been on a low dosage.....200 mg a 
day......thank-you 
rob

From: skink1100 <[email protected]>
To: CMLHope <[email protected]> 
Sent: Monday, March 12, 2012 1:54 PM
Subject: [CMLHope] loss of effectiveness of gleevec and sprycel

I have had cml for nearly 10 years.  For several years I was at the
not detectable level in my pcr tests.  Last year the gleevec seemed to
no longer be as effective...and my doctor switched me to
sprycel...about 4 months ago...my results continue to decline,
although my blood looks ok.  Has anyone had a similar
experience...could it be a new mutation?  Where does on go from
here...getting worried.

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A support group of http://cmlhope.com
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