Hi again,

WinCoot should not be restricted to one CPU any more. This was in the past. I 
am not sure what CCP4 may have done to the startup script though...

I located a potential issue in coot.bat, which you find in 
yourccp4directory/bin. This file has

"/affinity 1"

in the last line before (coot-bin.exe). Remove this and it should use all 
available CPUs. If it doesn’t we need to find another place where this may be 
set and/or the processors are restricted.

HTH,

B

***************************************************

Dr. Bernhard Lohkamp | Associate Professor/Lektor/Docent

Teaching Unit/Biomedicum D9
Dept. of Medical Biochemistry and Biophysics (MBB) |
Karolinska Institutet
SE-171 77 Stockholm
Sweden
+46 8 52487055
[email protected] | ki.se

> -----Original Message-----
> From: Mailing list for users of COOT Crystallographic Software
> <[email protected]> On Behalf Of Lisa Baker
> Sent: 09 April 2025 13:29
> To: [email protected]
> Subject: Further update on my issue below - WinCOOT running incredibly
> slow on Windows11.
>
> [You don't often get email from [email protected]. Learn why this is
> important at https://aka.ms/LearnAboutSenderIdentification ]
>
> WinCOOT is defaulting to only using 1 CPU in Windows11. Hence the slow
> performance. When you change this in Task Manager to use all processors
> then it performs as it should.
>
> Can a setting be changed within WinCOOT so it defaults to use all processors
> as at the moment we're having to do this in Task manager every time we
> open WinCOOT.
>
> Note this problem has affected multiple users on our site, all with varying PC
> specs.
>
>
>
>
> -----Original Message-----
> From: Mailing list for users of COOT Crystallographic Software
> <[email protected]> On Behalf Of Lisa Baker
> Sent: 08 April 2025 19:46
> To: [email protected]
> Subject: Re:
>
> Dear COOT developers/community,
>
> Has anyone else noticed a drop in performance of ligand fitting/refinement
> in WinCoot recently? The drag atom functionality and refinement is so slow
> that it is barely useable.
>
> I don’t know if recent COOT updates or Windows 11 updates are the cause
> but any help/diagnosis greatly appreciated.
>
> Best wishes,
> Lisa
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