Hi,

Perfect. Thanks for letting me know. I am in touch with CCP4 to make sure this 
goes in the next update!

B

***************************************************

Dr. Bernhard Lohkamp | Associate Professor/Lektor/Docent

Teaching Unit/Biomedicum D9
Dept. of Medical Biochemistry and Biophysics (MBB) |
Karolinska Institutet
SE-171 77 Stockholm
Sweden
+46 8 52487055
[email protected] | ki.se

> -----Original Message-----
> From: Lisa Baker <[email protected]>
> Sent: 09 April 2025 13:58
> To: Bernhard Lohkamp <[email protected]>; [email protected]
> Subject: RE:
>
> Hi Bernhard,
>
> That worked! Thank you so much for your swift help on this issue. COOT is
> now running as it should and is calling multiple processers by default every
> time we open it from CCP4i2.
>
> Thank you once again,
> Lisa
>
>
>
> -----Original Message-----
> From: Bernhard Lohkamp <[email protected]>
> Sent: 09 April 2025 12:43
> To: Lisa Baker <[email protected]>; [email protected]
> Subject: RE: Further update on my issue below - WinCOOT running incredibly
> slow on Windows11.
>
>
> Hi again,
>
> WinCoot should not be restricted to one CPU any more. This was in the past.
> I am not sure what CCP4 may have done to the startup script though...
>
> I located a potential issue in coot.bat, which you find in
> yourccp4directory/bin. This file has
>
> "/affinity 1"
>
> in the last line before (coot-bin.exe). Remove this and it should use all
> available CPUs. If it doesn't we need to find another place where this may be
> set and/or the processors are restricted.
>
> HTH,
>
> B
>
> ***************************************************
>
> Dr. Bernhard Lohkamp | Associate Professor/Lektor/Docent
>
> Teaching Unit/Biomedicum D9
> Dept. of Medical Biochemistry and Biophysics (MBB) | Karolinska Institutet
> SE-171 77 Stockholm
> Sweden
> +46 8 52487055
> [email protected] | ki.se
>
> > -----Original Message-----
> > From: Mailing list for users of COOT Crystallographic Software
> > <[email protected]> On Behalf Of Lisa Baker
> > Sent: 09 April 2025 13:29
> > To: [email protected]
> > Subject: Further update on my issue below - WinCOOT running incredibly
> > slow on Windows11.
> >
> > [You don't often get email from [email protected]. Learn why this
> > is important at https://aka.ms/LearnAboutSenderIdentification ]
> >
> > WinCOOT is defaulting to only using 1 CPU in Windows11. Hence the slow
> > performance. When you change this in Task Manager to use all
> > processors then it performs as it should.
> >
> > Can a setting be changed within WinCOOT so it defaults to use all
> > processors as at the moment we're having to do this in Task manager
> > every time we open WinCOOT.
> >
> > Note this problem has affected multiple users on our site, all with
> > varying PC specs.
> >
> >
> >
> >
> > -----Original Message-----
> > From: Mailing list for users of COOT Crystallographic Software
> > <[email protected]> On Behalf Of Lisa Baker
> > Sent: 08 April 2025 19:46
> > To: [email protected]
> > Subject: Re:
> >
> > Dear COOT developers/community,
> >
> > Has anyone else noticed a drop in performance of ligand
> > fitting/refinement in WinCoot recently? The drag atom functionality
> > and refinement is so slow that it is barely useable.
> >
> > I don't know if recent COOT updates or Windows 11 updates are the
> > cause but any help/diagnosis greatly appreciated.
> >
> > Best wishes,
> > Lisa
> >
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