Hi Chris,

   A colleague of mine has found a few possible examples of
"self-assembling code" but they are not strings of bits, they are better
described as a form of topological object. They are based on a different
model of computation:
http://chorasimilarity.wordpress.com/2014/09/01/quines-in-chemlambda/


On Mon, Sep 1, 2014 at 2:45 PM, 'Chris de Morsella' via Everything List <
[email protected]> wrote:

>
>
>
>
> *From:* [email protected] [mailto:
> [email protected]] *On Behalf Of *John Clark
> *Sent:* Monday, September 01, 2014 9:43 AM
>
> *To:* [email protected]
> *Subject:* Re: AI Dooms Us
>
>
>
> On Sun, Aug 31, 2014 at 3:18 PM, 'Chris de Morsella' via Everything List <
> [email protected]> wrote:
>
>
>
> > Just want to point out that the process of DNA expression is highly
> dynamic and is multi-factored
>
>
>
> Yes it certainly is, but however dynamic the DNA information is it's still
> just 750 meg (actually it's much less than that considering the massive
> amount of redundancy in our genome). And Telmo's 1000 lines of lisp would
> also have to be highly dynamic.
>
>
>
> Amazing isn’t it. The elegance of self-assembling processes that can do so
> much with so little input. I doubt 1000 lines of computer code is a large
> enough initial instruction set even for a highly self-generating system.
> Maybe a few million lines of code might do it though, if it was code that
> generated other code and so forth in a cascading process similar to
> embryogenesis in eukaryotes.
>
> > The mammalian genomes undergo very extensive genomic reprogramming
> during embryogenesis.
>
>
>
> And where did the information about how to do that reprogramming come
> from? From the original 750 meg.
>
>
>
> Much of it did certainly. But it also comes from the environment… e.g.
> from an external source. The outcome of embryogenesis is affected by
> epigenetic influences that alter what genetic information is expressed and
> also crucially when (at what point in sequences of expression) it occurs.
> This external epigenetic programming instructions are completely outside of
> that original bundle of genetic information.
>
>
>
>
> > This is especially so during the process of embryogenesis, an unfolding
> developmental choreographed switching process that is controlled by
> epigenetic programming (methylation /demethylation and other mechanisms).
>
>
> Methylation means that occasionally a Methyl group might be added to one
> of the DNA bases, a base would have a Methyl group or it would not so it's
> still digital. There are 4 bases so AT MOST each of the 3 billion bases
> would represent 3 bits instead of 2, so the information content would
> increase from 750 Meg to 1.12 Gig and with a file compression program like
> ZIP you could still fit all of it on a CD.
>
> But the fact is that the epigenetic external information is not available
> until run-time. It exists outside the organism in its environment.
>
> But in reality Epigenetic information is pretty clearly of minor
> importance compared with the DNA sequence information, so I doubt it would
> even cause it to increase to 751 Meg. And the evidence that Epigenetic
> heredity exists for more than one generation is very meager.
>
>
>
> I do not agree that the understanding and quantification of epigenetic
> influences on human development (especially during embryogenesis) is as
> settled or of minor consequence as you state. There is evidence for example
> that it persists for three generations in studies of cigarette smokers
> progeny, and I have read studies that point to high stress in one
> generation resulting in epigenetic hereditary outcomes in subsequent
> generations. Even identical twins as they grow and live through their
> different lives – even their originally identical DNA diverges in its
> expressed outcome due to epigenetic affects.
>
> > DNA is not a direct single layered – single meaning -- instruction set
> encoded and fixed.
>
>
>
> You can assign as many layers of meaning on it as you like but nothing can
> change the fact that you could put all the information in the entire human
> DNA genome on a old fashioned CD and still have enough room on it for a
> Beatles album from 1965.
>
>
>
> And 32 or so fundamental values define (fix, quantify) all the laws of our
> universe. Amazing complexity can emerge from simple initial conditions.
>
>
>
> >  The same strand of DNA, depending on the dynamic action of the large
> number of transcription factors
>
>
>
> A transcription factors is just a protein that binds to specific DNA
> sequences. And where did the information come from to know what sequence of
> amino acids will build that very important protein? From the original 750
> Meg of course.
>
> From that original bundle of genetic code + environmental influences. 90%
> of the living things in a human body DO NOT have human DNA (not by weight
> of course but by census)… our behavior, our desires, our decisions, our
> thoughts, dreams, cravings, fears… our volition… is at least in part being
> driven by these other non-human organisms (especially the huge diverse
> community of microorganisms living in our guts).
>
> The kind of flora and fauna we have in our guts in many ways determines
> who we are, what we think and what we desire. It affects out well-being (or
> lack of it), our emotions and our goals. This genetic information is not
> part of the human DNA, but humans have coevolved with these communities of
> microorganisms and many of them play important (perhaps vital) roles in our
> Darwinian fitness.
>
> The information that triggers a whole slew of affects resulting in a
> changed outcome for the organism could very well have originated in some
> microorganism inhabiting that individuals gut. Our immune system especially
> seems to have co-evolved to work symbiotically with many different species
> of microorganisms.
>
> We require a vast library of CDs to live healthy lives…. Not just our DNA
> CD, but all the DNA CDs of the thousands of organisms that a healthy human
> animal requires (or greatly benefits from having within them). We are not
> isolated organisms apart from the many other cohabitating organisms that
> journey through life living inside our bodies.
>
> > It is – IMO – necessary to understand DNA as [...]
>
>
>
> I'm not saying that understanding how 750 Meg of DNA information manages
> to produce a human being will be easy, figuring out how Telmo's 1000 lines
> of lisp works will not be easy either, but I am saying that's all the
> information there is.
>
>   John K Clark
>
>
>
> I agree that it is amazingly compact. We may differ on where we draw the
> line. I do not see a single human (or other eukaryote) only in terms of its
> own DNA + epigenetic meta-programming over the DNA base, but also in terms
> of the ecosystem that exists within.  Both the beneficial and the parasitic
> species within us hugely affect our lives – as they do with every
> multi-cellular species we know about.
>
> We are walking talking ecosystems with biotic auras as unique as
> fingerprints (in fact forensic science is beginning to study this as a
> potential investigative tool)
>
> -Chris
>
>
>
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-- 

Kindest Regards,

Stephen Paul King

Senior Researcher

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[email protected]

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