On Fri, Jul 31, 2020 at 9:35 PM 'Brent Meeker' via Everything List < [email protected]> wrote:
> > > On 7/31/2020 5:49 PM, Jason Resch wrote: > > > > On Fri, Jul 31, 2020 at 7:37 PM PGC <[email protected]> wrote: > >> >> >> On Saturday, August 1, 2020 at 2:26:40 AM UTC+2, Jason wrote: >>> >>> >>> >>> On Fri, Jul 31, 2020 at 7:20 PM PGC <[email protected]> wrote: >>> >>>> >>>> >>>> On Saturday, August 1, 2020 at 1:12:49 AM UTC+2, Jason wrote: >>>>> >>>>> There have been 65 studies on HCQ. Of all the tests that looked at >>>>> giving it early in the disease, or prophylactically, they showed HCQ was >>>>> beneficial. This site summarizes them all: https://c19study.com/ >>>>> >>>>> The only studies that have shown HCQ to be ineffective are those where >>>>> it is given late in the disease progression (when the disease shifts from >>>>> the viral replication phase to an immune system dysregulation phase >>>>> <https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdf> >>>>> (see page 2)). Even then, 61% of studies have shown some effectiveness >>>>> even >>>>> when it is given late. >>>>> >>>>> Given the well-established safety >>>>> <https://www.cdc.gov/malaria/resources/pdf/fsp/drugs/Hydroxychloroquine.pdf> >>>>> record of HCQ, this is the dilemma we face: >>>>> >>>>> >>>>> HCQ works HCQ doesn't work >>>>> HCQ widely dispensed 10,000s of thousands of lives saved $20 wasted >>>>> per patient >>>>> HCQ use restricted 10,000s of thousands of needless deaths $0 wasted >>>>> per patient >>>>> >>>>> Even in the face of impartial information on its effectiveness, the >>>>> decision is clear. >>>>> >>>> >>>> >>>> https://www.who.int/news-room/detail/04-07-2020-who-discontinues-hydroxychloroquine-and-lopinavir-ritonavir-treatment-arms-for-covid-19 >>>> >>>> Why not find out from the WHO or the steering committee itself? Just be >>>> prepared to wait as I believe they are somewhat busy. >>>> >>>> But contact them >>>> >>> >>> Find out what from the WHO? >>> >> >> Why they discontinued the treatment arm and why you think they should >> re-establish it (again btw) to save thousands of lives, with your table and >> the website. PGC >> >>> >> > It's purely a decision theory problem. They WHO is not infallible (and > have demonstrated that recently), the science on HCQs effectiveness is > mixed, the science on its safety is clear. > > Given that there is a clearly optimal decision with a higher expected > value. > > > No, there is not. The trials show some improvement for ill persons. > One study found early use reduced hospitalizations by 84% deaths by 80%. That's hardly insignificant. What's the downside risk, as you perceive it? > It doesn't show there would be no harm in using it as a preventative in > well persons. > That has been established by the 60 year history of use by tens of millions of people. See the CDC link I gave, it's safe even for pregnant and nursing mothers. Jason > > Brent > > > The very link you provided says they only cancelled only the late stage > testing. They are continuing early and prophylactic use tests. > > "This decision applies only to the conduct of the Solidarity trial in > hospitalized patients and does not affect the possible evaluation in other > studies of hydroxychloroquine or lopinavir/ritonavir in non-hospitalized > patients or as pre- or post-exposure prophylaxis for COVID-19." > > > Jason > -- > You received this message because you are subscribed to the Google Groups > "Everything List" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > To view this discussion on the web visit > https://groups.google.com/d/msgid/everything-list/CA%2BBCJUiQtZttiHSVszjVzUWyjZf60wUTPJwS8AYVFytgjj-gYQ%40mail.gmail.com > <https://groups.google.com/d/msgid/everything-list/CA%2BBCJUiQtZttiHSVszjVzUWyjZf60wUTPJwS8AYVFytgjj-gYQ%40mail.gmail.com?utm_medium=email&utm_source=footer> > . > > > -- > You received this message because you are subscribed to the Google Groups > "Everything List" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to [email protected]. > To view this discussion on the web visit > https://groups.google.com/d/msgid/everything-list/50c6dc2f-23a7-dad7-d47b-2fa503cbc348%40verizon.net > <https://groups.google.com/d/msgid/everything-list/50c6dc2f-23a7-dad7-d47b-2fa503cbc348%40verizon.net?utm_medium=email&utm_source=footer> > . > -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To view this discussion on the web visit https://groups.google.com/d/msgid/everything-list/CA%2BBCJUhzgvwrx1xMWp7NGDgogDZCCLSR5bq88Ro6G6_wrxKfnQ%40mail.gmail.com.
