That's an interesting paper! Note that the theoretical physicist Paul
Davies is the one who took the initiative to set up this prize and he is
strong skeptic against all current approaches in prebiotic chemistry.
I've read the work of his research group (Paul Davies and Sara Walker),
their no-go arguments are quite strong, but they don't propose solutions
that I find all that attractive. That led me to do my own work in this
field.
Saibal
On 19-01-2021 18:01, Evgenii Rudnyi wrote:
I do not know if you have seen this paper:
Molecular Codes in Biological and Chemical Reaction Networks
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054694
They claim that in random chemical networks one can find some semantic:
"High semantic capacity was found in the studied biochemical systems
and in random reaction networks where the number of second order
reactions is twice the number of species."
I guess that they should apply for the prize.
Evgeny
Am 19.01.2021 um 00:58 schrieb smitra:
On 18-01-2021 18:03, Evgenii Rudnyi wrote:
Am 18.01.2021 um 01:01 schrieb Lawrence Crowell:
There are molecules that already do this. DNA and polypeptides are
sequences that are in effect codes.
Yes, this is exactly the point by the prize. The question is to show
how something like this could happen spontaneously.
Evgeny
It requires violating local thermodynamic equilibrium. I'm working on
an article and a few presentations for upcoming conferences where I
explain this in detail. This then proves that none of the current
models for prebiotic chemistry can explain the origin of life. A
viable scenario is to get to a large random organic structure forged
in an interstellar ice grain, where organic molecules at low
temperatures under UV irradiation will only interact with nearest
neighbors. Thermodynamic equilibrium is never reached, the system
moves farther and farther away from this as the reactions under UV
radiation continue. This way one gets to large so-called percolation
clusters of organic molecules that have a random structure.
Such random organic structures look totally useless to explain the
origin of life, because what you want are the very specific molecules
that are involved in the biochemical processes in living organisms.
However, the structure of these random organic molecules is such that
it has interior structures with compartments containing large random
polymers and random interior surface structures. These can then serve
as micro-environments within which prebiotic chemistry under normal
local thermodynamic equilibrium conditions can work. With a finite
number of N structures in a compartment one will break symmetries such
as chiral symmetry at a level of 1/sqrt(N). Small molecules can escape
the compartments via pores in the random structure while large
molecules get trapped inside.
Saibal
LC
On Monday, January 4, 2021 at 12:28:18 PM UTC-6 [email protected]
wrote:
"How do you get from chemicals to code? How do you get a code
without
designing one?"
"What You Must Do to Win The Prize
You must arrange for a digital communication system to emerge or
self-evolve without "cheating." The diagram below describes the
system.
Without explicitly designing the system, your experiment must
generate
an encoder that sends digital code to a decoder. Your system needs
to
transmit at least five bits of information. (In other words it has
to be
able to represent 32 states. The genetic code supports 64.) "
https://www.herox.com/evolution2.0
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