Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital.
I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don´t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don´t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 às 14:18, Amani Oakley <[email protected]> escreveu: > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion – > and mine alone – my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk <[email protected]> * On Behalf Of > *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* [email protected] > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patrícia > > > > Em ter, 4 de jun de 2019 às 23:46, Amani Oakley <[email protected]> > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk <[email protected]> *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* [email protected] > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 às 20:50, Lorraine Johnston < > [email protected]> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:[email protected]] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* [email protected] > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don´t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patrícia > > > > Em sáb, 1 de jun de 2019 às 14:44, Amani Oakley <[email protected]> > escreveu: > > Hi Patricia – I gave all the pills together, morning and evening, except > for the metoclopramide which was given ½ or so before meals. The rest I > gave with the meals. I didn’t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn’t eating (and he wasn’t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > – say – five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk <[email protected]> *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* [email protected] > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn´t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > <https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A> > > > > > > Thank you! > > > > Patrícia > > > > Em qui, 30 de mai de 2019 às 20:52, Amani Oakley <[email protected]> > escreveu: > > Sorry Patricia – after going on and on in my last email, I realized I > hadn’t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk <[email protected]> *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* [email protected] > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patrícia > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > [email protected] > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >
_______________________________________________ Felvtalk mailing list [email protected] http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
