Hi, Amani

Nori is receiving doxy+prenisolone+stanazolol even in the hospital.

I know it can be a reaction but i thought higher dose of prednisolone would
prevent hemolysis.

I also know it's normal for part of the red blood cells to be cleared right
after the transfusion, but i don´t remember if it was icteric plasma on
last one.

I was hopefull she would come back home tomorrow, now i don´t know if it
will be possible.

Today she must have am echocardiogram too because x-ray showed an enlarged
heart.

Thank you!



Em sex, 7 de jun de 2019 às 14:18, Amani Oakley <aoak...@oakleylegal.com>
escreveu:

> Hi Patricia
>
>
>
> The Stanozolol often has a side-effect of elevating liver enzymes, though
> I cannot remember if it also increased bilirubin (which would be what would
> cause the icteric observation of the plasma). However, hang in there. If it
> is the Stanozolol, my experience is that the liver enzymes drop right back
> to normal, shortly after it is discontinued, and there is no lasting damage
> to the liver. For now, what you have described (low temp and slightly lower
> heart rate) seems more likely to be related to the transfusion itself,
> rather than anything else going on.
>
>
>
> It is also possible that with the additional transfusion, there is a
> higher than normal red cell destruction going on, which would be another
> explanation for the increased icterus in the blood (which will also show as
> an increase in bilirubin). Elevated bilirubin can often be caused by a
> reaction to a blood transfusion. If the high bilirubin is the indirect or
> the unconjugated portion, it is related to red cell break down. The direct
> bilirubin (conjugated portion) is related to liver function. The lab
> results are usually broken down to Total bilirubin and Direct bilirubin.
> The indirect portion is obtained by subtracting the direct amount from the
> total amount.
>
>
>
> I myself went through the pressure of the vets wanting me to discontinue
> the Stanozolol because of abnormal liver enzymes. My logic was that there
> was nothing else. If I discontinued the Stanozolol, my cat would die,
> period. I continued and found that in the end, the liver enzymes normalized
> on their own, even though I had Zander on almost continuous Stanozolol for
> close to two years.
>
>
>
> I know that you know that you are only temporarily helping Nori with blood
> transfusions, and the virus is still attacking cells, etc. In my opinion –
> and mine alone – my experience and research leads me to the conclusion that
> the combination of Doxycycline/Prednisone/Stanozolol worked to not only
> boost the red cell production, but I believe that the Doxycyline assisted
> in keeping the viruses from properly reproducing.
>
>
>
> However, anticipate that when the vet gets back the second set of blood
> work, she may well try to tell you to discontinue the Stanozolol.
>
>
>
> Amani
>
>
>
>
>
>
>
> *From:* Felvtalk <felvtalk-boun...@felineleukemia.org> * On Behalf Of 
> *Patricia
> Oliveira
> *Sent:* June 7, 2019 12:53 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* Re: [Felvtalk] Rescued kitten felv +
>
>
>
> Hi, Amani!
>
>
>
> Nori got another transfusion last night, hematocrit was 11.9 before it.
>
>
>
> Today morning, i talk to the hospital's veterinarian, she said hematocrit
> went to 29 and Nori was fine, all normal parameters and eating by herself
> again.
>
>
>
> But plasma was intensely icteric. I think this means red cells being
> destroyed, isn't it?
>
>
>
> About one hour ago, veterinarian said Nori was with low temperature and
> heart rate slightly lower than normal. She was waiting the new blood work.
> In the morning, it was done only hematocrit, not complete blood work.
>
>
>
> i am worried again.
>
>
>
> Thank you,
>
>
>
> Patrícia
>
>
>
> Em ter, 4 de jun de 2019 às 23:46, Amani Oakley <aoak...@oakleylegal.com>
> escreveu:
>
> I would be leery of the going the route suggested by the vet at this
> juncture. I seriously seriously doubt if the erythropoietin will help. See
> my earlier where I explain why.
>
>
>
> Amani
>
>
>
> *From:* Felvtalk <felvtalk-boun...@felineleukemia.org> *On Behalf Of *Patricia
> Oliveira
> *Sent:* June 4, 2019 8:53 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* Re: [Felvtalk] Rescued kitten felv +
>
>
>
> Hi, Lorraine
>
>
>
> Veterinary wants to increase prednisolone to immunosuppressive dose and
> add erythropoietin. She thinks it is immune-mediated anemia and
> not mycoplasma.
>
>
>
> Nori is receiving  1,2 mg prednisolone, twice a day. She weighs only 1 kg.
>
>
>
> We did x-ray today too. No visible tumor but we found a
> possible cardiopathy ("Increased globular-looking heart silhouette").
>
>
>
> :(
>
>
>
>
>
>
>
> Em ter, 4 de jun de 2019 às 20:50, Lorraine Johnston <
> johnston1...@comcast.net> escreveu:
>
> Patricia,
>
>
>
> I would go with the transfusion and also start erythropoietin.  Stanozolol
> is supposed to stimulate erythropoietin production, but she might need a
> boost of the ready-made drug just to keep her alive until then.
>
>
>
> - Lorraine
>
>
>
> "Sometimes it is the people no one can imagine anything of who do the
> things no one can imagine."  - Alan Turing
>
>
>
> *From:* Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] *On Behalf
> Of *Patricia Oliveira
> *Sent:* Tuesday, June 4, 2019 6:34 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* Re: [Felvtalk] Rescued kitten felv +
>
>
>
> Hi,
>
>
>
> We did another blood work today, her hematocrit is 13% now :(
>
>
>
> She is very sleepy but responsive when i talk to her.
>
>
>
> I don´t know if i can wait some more days to see if stanozolol is working.
> Or maybe it would be better get another transfusion right now.
>
>
>
> Today, vet talk about erythropoietin. Do you know if it can be used with
> stanozolol?
>
>
>
> Thank you,
>
>
>
> Patrícia
>
>
>
> Em sáb, 1 de jun de 2019 às 14:44, Amani Oakley <aoak...@oakleylegal.com>
> escreveu:
>
> Hi Patricia – I gave all the pills together, morning and evening, except
> for the metoclopramide which was given ½ or so before meals. The rest I
> gave with the meals. I didn’t observe a problem with giving them together.
>
>
>
> You might also try baby food to get Nori to eat. Get the pureed kind (beef
> or chicken with or without vegetables), so it can be sucked up into a
> syringe. If my Zander wasn’t eating (and he wasn’t at the start of the
> medication regime), then I would use a syringe to get the baby food into
> him. Baby food is easy to digest and has good things in it. I would target
> – say – five 3 cc syringe-fulls at each feeding. I would boost the number
> of syringe-fulls if possible. Eventually, Zander started eating the baby
> food on his own, and then I graduated to moist food, and really, anything
> he wanted until he put the weight back on.
>
>
>
> I had a look at the picture you sent and Nori is adorable. I am crossing
> my fingers for you and for Nori. Keep us updated on her progress.
>
>
>
> Amani
>
>
>
> *From:* Felvtalk <felvtalk-boun...@felineleukemia.org> *On Behalf Of *Patricia
> Oliveira
> *Sent:* June 1, 2019 12:36 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* Re: [Felvtalk] Rescued kitten felv +
>
>
>
> Hi, Amani!
>
>
>
> Thanky you very much for you email!
>
>
>
> Nori was discharged from the hospital yesterday night. She is eating baby
> dry food. I tried canned but she didn´t accept so weel.
>
>
>
> Today i bought other kinds of canned, i'll try them hoping she likes some
> one.
>
>
>
> Compound pharmacy must delivery stanozolol today.
>
>
>
> Are there any precautions regarding medication schedules? Close or far to
> doxy, for example?
>
>
>
> This is Nori:
> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html
> <https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A>
>
>
>
>
>
> Thank you!
>
>
>
> Patrícia
>
>
>
> Em qui, 30 de mai de 2019 às 20:52, Amani Oakley <aoak...@oakleylegal.com>
> escreveu:
>
> Sorry Patricia – after going on and on in my last email, I realized I
> hadn’t actually answered your question. I think you can probably use the
> stanozolol with the Doxycycline, without the prednisone, but prednisone
> itself has properties which help to boost red cell production. Try it out,
> keep close tabs on the haematology results and see if you are getting a
> good response on just Doxycycline and the Stanozolol. If not, add the
> prednisone. You may find that this combination assists with the FIP as
> well, as per my previous email.
>
>
>
> Amani
>
>
>
> *From:* Felvtalk <felvtalk-boun...@felineleukemia.org> *On Behalf Of *Patricia
> Oliveira
> *Sent:* May 30, 2019 12:56 PM
> *To:* felvtalk@felineleukemia.org
> *Subject:* [Felvtalk] Rescued kitten felv +
>
>
>
> Hi from Brazil,
>
>
>
> I rescued a very weak, dehydrated, extremely thin kitten.
>
>
> She's hospitalized now. Her hematocrit was 8, had blood transfusion which
> raised hematocrit to 22, now it is 19. Low reticulocyte count.
>
> She has difficulty walking, which we can not define if it is just weakness
> or neurological. Already had a seizure.
>
> She also have changes in her kidneys. It has been tested and is felv +
>
> She is receiving doxy and the hospital vets would like to include
> prednisolone.
>
> However, as it is not possible yet to rule out PIF, and the medication I
> could use in the case of PIF does not work if the cat received
> prednisolone, I am trying to avoid it.
>
> The veterinarian agreed to prescribe stanozolol.
>
> Can it be used without prednisolone, only with doxy she is already
> receiving?
>
> Thank you!
>
>
>
> Patrícia
>
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